- Macrophages, myofibroblasts and mast cells in a rat liver infected with Capillaria hepatica
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Jeong WI, Do SH, Hong IH, Ji AR, Park JK, Ki MR, Park SC, Jeong KS
- KMID: 1106239
- J Vet Sci.
- 2008 Jun;9(2):211-213.
- doi: 10.4142/jvs.2008.9.2.211
We trapped a rat (Rattus norvegicus) infected with Capillaria hepatica. At necropsy, grossly yellowish-white nodules (2-3 mm in diameter) were noted to be scattered on the liver's surface. Microscopically, granulomatous... -
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- MyD88-BLT2-dependent cascade contributes to LPS-induced interleukin-6 production in mouse macrophage
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Lee AJ, Cho KJ, Kim JH
- KMID: 2070275
- Exp Mol Med.
- 2015 Apr;47(4):e156.
- doi: 10.1038/emm.2015.8
Endotoxic responses to bacterial lipopolysaccharide (LPS) are triggered by Toll-like receptor 4 (TLR4) and involve the production of inflammatory mediators, including interleukin-6 (IL-6), by macrophages. The detailed mechanism of IL-6... -
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- The macrophage migration inhibitory factor protein superfamily in obesity and wound repair
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Kim BS, Pallua N, Bernhagen , Bucala R
- KMID: 2155653
- Exp Mol Med.
- 2015 May;47(5):e161.
- doi: 10.1038/emm.2015.26
The rising number of obese individuals has become a major burden to the healthcare systems worldwide. Obesity includes not only the increase of adipose tissue mass but importantly also the... -
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- Hemophagocytic Syndrome in a Patient with Acute Tubulointerstitial Nephritis Secondary to Hepatitis A Virus Infection
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Cho E, Cha I, Yoon K, Yang HN, Kim HW, Kim MG, Jo SK, Cho WY, Kim HK
- KMID: 2157862
- J Korean Med Sci.
- 2010 Oct;25(10):1529-1531.
- doi: 10.3346/jkms.2010.25.10.1529
Hepatitis A virus (HAV) infection is generally a self-limited disease, but the infection in adults can be serious, to be often complicated by acute kidney injury (AKI) and rarely by... -
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- Restoration of Adriamycin and Vincristine Dependent Tumoricidal Activity by Interferon in Mice with Implanted Tumor Cells
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Lee WY, Lee BK, Kim BS
- KMID: 1729538
- Yonsei Med J.
- 1987 Jun;28(2):91-97.
- doi: 10.3349/ymj.1987.28.2.91
The survival of implanted tumor cells in mice which had been treated with interferon in combination with either adriamycin or vincristine was evaluated. While the majority of tumor cells implanted... -
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- Suppression of CD4+ T-Cells in the Spleen of Mice Infected with Toxoplasma gondii KI-1 Tachyzoites
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Kim WH, Shin EH, Kim JL, Yu SY, Jung BK, Chai JY
- KMID: 1104700
- Korean J Parasitol.
- 2010 Dec;48(4):325-329.
- doi: 10.3347/kjp.2010.48.4.325
Toxoplasma gondii KI-1, a recent new isolate from Korea, shows similar pathogenicity and infectivity to mice compared to the virulent RH strain. To understand characteristics of host immunity, including immune... -
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- Experimental orthotopic penetrating keratoplasty--a rat penetrating keratoplasty model
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Tchah H, Youn DH, Holland EJ
- KMID: 1421510
- J Korean Med Sci.
- 1991 Mar;6(1):15-19.
- doi: 10.3346/jkms.1991.6.1.15
An orthotopic penetrating keratoplasty model was developed in the rat. An oversized (0.5 mm) graft was used and 8 interrupted sutures were applied. These sutures were not removed. Eleven grafts... -
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- Role of IL-1alpha in Cisplatin-Induced Acute Renal Failure in Mice
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Lee JW, Nam WJ, Han MJ, Shin JH, Kim JG, Kim SH, Kim HR, Oh DJ
- KMID: 1776591
- Korean J Intern Med.
- 2011 Jun;26(2):187-194.
- doi: 10.3904/kjim.2011.26.2.187
BACKGROUND/AIMS: For unknown reasons, caspase-1 -/- mice, protected against cisplatin-induced acute renal failure (ARF), are deficient in interleukin (IL)-1alpha. We thus asked whether IL-1alpha deficiency underlies the mechanism of protection... -
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- Prominent IL-12 Production and Tumor Reduction in Athymic Nude Mice after Toxoplasma gondii Lysate Antigen Treatment
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Pyo KH, Jung BK, Xin CF, Lee YW, Chai JY, Shin EH
- KMID: 2069810
- Korean J Parasitol.
- 2014 Dec;52(6):605-612.
- doi: 10.3347/kjp.2014.52.6.605
Toxoplasma gondii is an intracellular protozoan parasite that causes a Th1 cellular immunity. Our previous study showed that T. gondii lysate antigen (TLA) treatment in S180 tumor-bearing mice resulted in... -
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- Toll-like receptor 4 on islet beta cells senses expression changes in high-mobility group box 1 and contributes to the initiation of type 1 diabetes
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Li M, Song L, Gao X, Chang W, Qin X
- KMID: 1365903
- Exp Mol Med.
- 2012 Apr;44(4):260-267.
- doi: 10.3858/emm.2012.44.4.021
Type 1 diabetes mellitus is caused by the autoimmune destruction of beta cells within the islets. In recent years, innate immunity has been proposed to play a key role in... -
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- Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis
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Jue DM, Jeon KI, Jeong JY
- KMID: 646299
- J Korean Med Sci.
- 1999 Jun;14(3):231-238.
- doi: 10.3346/jkms.1999.14.3.231
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by persistent joint swelling and progressive destruction of cartilage and bone. Current RA treatments are largely empirical in origin and their... -
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- Nuclear Molecular Imaging for Vulnerable Atherosclerotic Plaques
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Lee SJ, Paeng JC
- KMID: 2160762
- Korean J Radiol.
- 2015 Oct;16(5):955-966.
- doi: 10.3348/kjr.2015.16.5.955
Atherosclerosis is an inflammatory disease as well as a lipid disorder. Atherosclerotic plaque formed in vessel walls may cause ischemia, and the rupture of vulnerable plaque may result in fatal... -
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- Paradoxical effects of elastase inhibitor guamerin on the tissue repair of two different wound models: sealed cut and exposed tongue wounds
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Lee SK, Lee SS, Song IS, Kim YS, Park YW, Joo JY, Um HS, Kim JW, Kim KY, Choi SJ, Jung KH, Chung SI
- KMID: 1097108
- Exp Mol Med.
- 2004 Jun;36(3):259-267.
Innate elastase inhibitors are known to be putatively involved in the regulation of tissue inflammation by inhibiting polymorphonuclear leukocyte (PMN) derived proteinases. The aim of this study was to evaluate... -
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