- Interpretation of Liver Function Tests
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Kim YJ
- KMID: 782993
- Korean J Gastroenterol.
- 2008 Apr;51(4):219-224.
Liver function tests (LFT) are helpful screening tools to detect hepatic dysfunction. LFT are further used to categorize hepatic dysfunctions, to estimate the severity of hepatic disease, and for the... -
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- Arylamine N-methyltransferase and thiol methyltransferase activities in cholestatic rat liver induced by common bile duct ligation
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Kim YH, Joo I
- KMID: 755113
- Exp Mol Med.
- 2001 Mar;33(1):23-28.
Methylation catalyzed by methyltransferases is a major metabolic pathway for an inactivation of some catecholamines, niacinamide as well as aliphatic sulfhydryl drugs and toxic hydrogen sulfides. To investigate the effects... -
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- Liver Cells of Cordotomized Rats after Single Doses of Carbon Tetrachloride
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Shin TS, Choi KD
- KMID: 687640
- Yonsei Med J.
- 1970 Dec;11(2):85-94.
- doi: 10.3349/ymj.1970.11.2.85
In attempting to ellucidate the mechanism of action of CCl4 toxicity on the liver, the histobgical and histochemical studies were carried out, at the cellular or ultrastructural level, rats were... -
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- Purification and cloning of glyoxalase II from rat liver
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Cho MY, Bae CD, Park JB, Lee TH
- KMID: 754988
- Exp Mol Med.
- 1998 Mar;30(1):53-57.
Glyoxalase (GLO) II, which is a component of GLO system and catalyze the conversion of S-lactoyl-glutathione to D-lactate, was purified 1488 fold from rat liver by two steps of Affigel blue and... -
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- A Study of the Regulation of the Glucose Transporter in the Plasma Membranes of Hepatoma Cells Induced by 3'-Me DAB
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Ahn YH, Chai KJ, Kim SN, Kim YS
- KMID: 693085
- Yonsei Med J.
- 1987 Sep;28(3):192-198.
- doi: 10.3349/ymj.1987.28.3.192
5'-nucelotidase and glucose-6-phosphatase are liver plasma and microsomal membranes markers and their respective activities were determined. In the liver homogenate, the activities of 5'-nucleotidase were 0.58 +/- 0.08 and 0.29... -
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- Prednisolone and Glucose-6-phosphatase Activity in Liver Cells
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Shin TS, Chung IH, Kim SS
- KMID: 687729
- Yonsei Med J.
- 1977 Jun;18(1):9-18.
- doi: 10.3349/ymj.1977.18.1.9
Prednisolone, a cortisol analogue, was given intraperitoneally to rats with 5, 10 or 15 doses of 5 mg. per kg. of body weight per day. Sacrificing the animals 24 hours... -
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- A case of amoxicillin-induced hepatocellular liver injury with bile-duct damage
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Kim JS, Jang YR, Lee JW, Kim JY, Jung YK, Chung DH, Kwon OS, Kim YS, Choi DJ, Kim JH
- KMID: 1025204
- Korean J Hepatol.
- 2011 Sep;17(3):229-232.
- doi: 10.3350/kjhep.2011.17.3.229
Amoxicillin, an antibiotic that is widely prescribed for various infections, is associated with a very low rate of drug-induced liver injury; hepatitis and cholestasis are rare complications. Here we present... -
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- Studies of Hepatic, Brain Monoamine Oxidase and Brain Serotonin in Rats
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Chai KJ, Kim YS
- KMID: 692972
- Yonsei Med J.
- 1984 Jun;25(1):27-38.
- doi: 10.3349/ymj.1984.25.1.27
The effects of 7-ethyl-8-methylf1avin (7-Et) and 7-methyl-8-ethyl-flavin (8-Et) on rat hepatic monoamine oxidase (MAO), brain MAO activity and 5-hydroxytryptamine (5-HT or serotonin) in rat brain were investigated. In the study... -
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- Effect of weight control on hepatic abnormalities in obese patients with fatty liver
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Park HS, Kim MW, Shin ES
- KMID: 927172
- J Korean Med Sci.
- 1995 Dec;10(6):414-421.
- doi: 10.3346/jkms.1995.10.6.414
This study was aimed at finding out whether weight reduction alone can improve liver function in obese patients with fatty liver. We did a longitudinal, clinical intervention study on weight... -
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- A Study of Hepatic Injury Induced by Endotoxin in Rats
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Lee DW, Kim CS, Lee YB, Kim DS
- KMID: 687759
- Yonsei Med J.
- 1978 Dec;19(2):19-34.
- doi: 10.3349/ymj.1978.19.2.19
To study the mechanism of endotoxin-induced hepatocellular injury in rats, a single dose of endotoxin, 15mg/kg, was injected intraperitoneally with or without dexamethasone pretreatment. Studies included light microscopic, histochemical, and... -
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- A Case of Nodular Regenerative Hyperplasia of the Liver Combined with Toxic Hepatitis
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Jin SM, Song SH, Cho YH, Shin DK, Shin SY, Kim GI, Park H, Rim KS
- KMID: 2373181
- Korean J Gastroenterol.
- 2015 Jan;65(1):52-56.
- doi: 10.4166/kjg.2015.65.1.52
Nodular regenerative hyperplasia (NRH) is an uncommon liver condition characterized by diffuse transformation of the hepatic parenchyma into regenerative nodules without fibrosis. Portal vasculopathy caused by abnormal hepatic venous flow... -
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- Enhancement of O-dealkylation in Mouse Liver by Dietary Administrations of BHA and BHT: Studies with Isolated Perfused Livers and Hepatic Microsomes
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Ji SC, Conway JG, Thurman RG, Cha YN
- KMID: 693021
- Yonsei Med J.
- 1986 Jun;27(2):106-113.
- doi: 10.3349/ymj.1986.27.2.106
Effects of feeding 2(3)-tert-butyl 4-hydroxyanisole (BHA) and 3, 5-di-tert-butyl 4-hydroxytoluene (BHT) on the rates of mixed function oxidation and conjugation enzyme reactions have been determined using isolated hepatic microsomal fractions... -
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- Glucose-6-phosphatase Activity and Ultrastructures in Hepatocytes of Thioacetamide-treated Mice
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Shin TS, Deung YK, Kim SS
- KMID: 687717
- Yonsei Med J.
- 1976 Dec;17(2):85-96.
- doi: 10.3349/ymj.1976.17.2.85
To investigate the earlier cellular alterations(Glucose-6-Pase activity and morphologic features) caused by a hepatotoxin, thioacetamide (TAA), a single dose of the agent (200mg per kg of body weight) was given... -
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- A variant of ornithine aminotransferase from mouse small intestine
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Lim SN, Rho HW, Park JW, Jhee EC, Kim JS, Kim HR
- KMID: 1109295
- Exp Mol Med.
- 1998 Sep;30(3):131-135.
The ornithine aminotransferase (OAT) activity of mouse was found to be highest in the small intestine. The mitochondrial OAT from mouse small intestine was purified to homogeneity by the procedures including heart... -
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- Liver dysfunction induced by systemic hypersensitivity reaction to lamotrigine: case report
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Im SG, Yoo SH, Park YM, Lee SJ, Jang SK, Jeon DO, Cho HJ, Oh MJ
- KMID: 2164369
- Clin Mol Hepatol.
- 2015 Jun;21(2):180-182.
- doi: 10.3350/cmh.2015.21.2.180
Lamotrigine is an anticonvulsant drug used to treat partial and generalized seizure disorders. Hypersensitivity to lamotrigine usually causes mild symptoms such as fever, rash, and slight invasion of internal organs.... -
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- Biochemical and Physiological Characteristics of Ca-ATPase System of Rat Liver Mitochondria with Special Attention to the Effects of pH and Temperature
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Lee SM, Hwang AR, Kim HJ, Park YS
- KMID: 692906
- Yonsei Med J.
- 1980 Dec;21(2):129-136.
- doi: 10.3349/ymj.1980.21.2.129
The activity of Mg++-dependent, Ca++-activated adenosine triphosphatase (Ca-ATPase) of rat liver mitochondria was studied at varying medium compositions, pH and temperatures. The enzyme system was characteristically sensitive to Ca++ concentration... -
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- Serum Gamma-Glutamyltransferase Concentration Correlates with Framingham Risk Score in Koreans
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Kim KN, Kim KM, Lee DJ, Joo NS
- KMID: 1785987
- J Korean Med Sci.
- 2011 Oct;26(10):1305-1309.
- doi: 10.3346/jkms.2011.26.10.1305
Gamma-glutamyltransferase (GGT) is a novel coronary artery disease (CAD) risk factor, but its use as an independent factor for CAD risk prediction remains unclear in Asian population. This study examined... -
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- Electron Microscopy on Activity and Localization of Glucose-6-phosphatase in Liver Cells
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Shin TS, Chung IH, Kim SS
- KMID: 687757
- Yonsei Med J.
- 1978 Dec;19(2):1-10.
- doi: 10.3349/ymj.1978.19.2.1
It is interesting and in important to study histochemical changes of glucose-6-phosphatase (G-6-Pase) activity by electron microscopy in order to promote the knowledge needed for diagnosis and prognosis in such... -
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- Regulation of acetyl CoA carboxylase mRNA in rat liver by high carbohydrate diet and insulin
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Choi DH, Choi JH, Whang SK, Kim YS
- KMID: 1097014
- Yonsei Med J.
- 1989 Sep;30(3):235-245.
- doi: 10.3349/ymj.1989.30.3.235
Acetyl CoA carboxylase contents in liver cytosol of rats refed a high carbohydrate diet or injected with insulin were measured by an immunoassay method in order to evaluate the... -
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- A Case of Lead Poisoning with Drug-induced Liver Injury after Ingestion of Herbal Medicine
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Jeon GJ, Park J, Kim MS, Yu JW, Park JH, Kim MS
- KMID: 2373241
- Korean J Gastroenterol.
- 2015 Jun;65(6):375-378.
- doi: 10.4166/kjg.2015.65.6.375
A 61-year-old male patient was admitted because of unexplained abdominal pain and anemia. His past medical history was unremarkable except for having taken herbal medicine to treat facial palsy two... -
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