- Histochemical and Cytogenetical Effects of Insulin on Mouse Liver in vivo and in vitro
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Hahn SS, Kim DS
- KMID: 687761
- Yonsei Med J.
- 1978 Dec;19(2):48-55.
- doi: 10.3349/ymj.1978.19.2.48
Histochemically detectable changes in the liver of the mouse after subcutaneous injection of a single sublethal does of insulin and the effect of insulin on mitotic rate and chromosome changes... -
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- Morphologic Effects of Oral Contraceptives (Norinyle) on the Guinea Pig Liver
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Kim CS, Lee YB
- KMID: 692896
- Yonsei Med J.
- 1980 Jun;21(1):43-51.
- doi: 10.3349/ymj.1980.21.1.43
In view of continuous clinical reports of liver damage following oral contraceptive use, morphologic changes of the liver following the administration of a combined type of oral contraceptive (Norinyle) were... -
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- Chronological effects of atherogenic diets on the aorta, liver and spleen of rabbits
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Song SH, Min BI, Lee JH, Cho KS
- KMID: 1730637
- J Korean Med Sci.
- 2000 Aug;15(4):413-419.
- doi: 10.3346/jkms.2000.15.4.413
To investigate the temporal progression of atherogenesis on the aorta and involvement of the monocyte-macrophage system in the liver and spleen, we fed 74 rabbits with high fat (14 or... -
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- Fine Structure Alteration of Rat Liver induced by Nitrosohexamethylenamine
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Kim CS, Greenblatt M
- KMID: 687635
- Yonsei Med J.
- 1970 Jun;11(1):31-44.
- doi: 10.3349/ymj.1970.11.1.31
The ultrastructural alterations in rat liver by feeding NHM(nitrosohexamethylenemine). These are described at intervals of 10 days, 5 weeks, 11 weeks, 14 weeks, 19 weeks, and 22 weeks. The group... -
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- Acute Drug-Induced Hepatitis Caused by Albendazole
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Choi GY, Yang HW, Cho SH, Kang DW, Go H, Lee WC, Lee YJ, Jung SH, Kim AN, Cha SW
- KMID: 1783081
- J Korean Med Sci.
- 2008 Oct;23(5):903-905.
- doi: 10.3346/jkms.2008.23.5.903
Albendazole binds to parasite's tubulin inhibiting its glucose absorption. Its common adverse effects are nausea, vomiting, constipation, thirst, dizziness, headache, hair loss and pruritus. Although mainly metabolized in the liver,... -
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- Liver Cells of Cordotomized Rats after Single Doses of Carbon Tetrachloride
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Shin TS, Choi KD
- KMID: 687640
- Yonsei Med J.
- 1970 Dec;11(2):85-94.
- doi: 10.3349/ymj.1970.11.2.85
In attempting to ellucidate the mechanism of action of CCl4 toxicity on the liver, the histobgical and histochemical studies were carried out, at the cellular or ultrastructural level, rats were... -
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- Effects of N-Acetylcysteine on Nicotinamide Dinucleotide Phosphate Oxidase Activation and Antioxidant Status in Heart, Lung, Liver and Kidney in Streptozotocin-Induced Diabetic Rats
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Lei S, Liu Y, Liu H, Yu H, Wang H, Xia Z
- KMID: 1120195
- Yonsei Med J.
- 2012 Mar;53(2):294-303.
- doi: 10.3349/ymj.2012.53.2.294
PURPOSE: Hyperglycemia increases reactive oxygen species (ROS) and the resulting oxidative stress plays a key role in the pathogenesis of diabetic complications. Nicotinamide dinucleotide phosphate (NADPH) oxidase is one of... -
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- Effect of Dexamethasone and Epinephrine on Metallothionein Level in the Perfused Rat Liver
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Lee HS, Oh SH
- KMID: 692893
- Yonsei Med J.
- 1980 Jun;21(1):18-23.
- doi: 10.3349/ymj.1980.21.1.18
The effect of dexamethasone (10(-5)M) and epinephrine (10(-6)M) on the biosynthesis of metallothionein (MT) in the perfused rat liver was investigated. MT synthesis was determined by measuring the incorporation of... -
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- Prednisolone and Glucose-6-phosphatase Activity in Liver Cells
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Shin TS, Chung IH, Kim SS
- KMID: 687729
- Yonsei Med J.
- 1977 Jun;18(1):9-18.
- doi: 10.3349/ymj.1977.18.1.9
Prednisolone, a cortisol analogue, was given intraperitoneally to rats with 5, 10 or 15 doses of 5 mg. per kg. of body weight per day. Sacrificing the animals 24 hours... -
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- Effects of prostaglandins on ethanol damage in primary cultured rat hepatocytes
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Yang JM, Choi SW, Kim SS, Sun HS, Park DH, Han SB, Oh GT, Kim WM
- KMID: 759062
- Korean J Intern Med.
- 1998 Feb;13(1):1-9.
OBJECTIVES: Several reports demonstrated that ethanol administration impairs the DNA synthesis in rat hepatocytes. Also, it has been demonstrated that prostaglandin (PG) helps prevent membrane damage by hepatotoxic chemicals. In ... -
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- Meta-analysis of randomized controlled trials of bosentan for treatment of pulmonary arterial hypertension
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Lee YH, Song GG
- KMID: 1780131
- Korean J Intern Med.
- 2013 Nov;28(6):701-707.
- doi: 10.3904/kjim.2013.28.6.701
BACKGROUND/AIMS: We assessed the efficacy and safety of bosentan in patients with pulmonary arterial hypertension (PAH). METHODS: We surveyed randomized controlled trials (RCTs) of the efficacy and safety of bosentan in... -
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- Glucose-6-phosphatase Activity and Ultrastructures in Hepatocytes of Thioacetamide-treated Mice
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Shin TS, Deung YK, Kim SS
- KMID: 687717
- Yonsei Med J.
- 1976 Dec;17(2):85-96.
- doi: 10.3349/ymj.1976.17.2.85
To investigate the earlier cellular alterations(Glucose-6-Pase activity and morphologic features) caused by a hepatotoxin, thioacetamide (TAA), a single dose of the agent (200mg per kg of body weight) was given... -
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- Glutathione recycling is attenuated by acute ethanol feeding in rat liver
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Oh SI, Kim CI, Chun HJ, Lee MS, Park SC
- KMID: 1081053
- J Korean Med Sci.
- 1997 Aug;12(4):316-321.
- doi: 10.3346/jkms.1997.12.4.316
The mechanism for ethanol-induced oxidative stress has been disputed because of the controversies on modulation of radical generating and scavenging activities by ethanol. In the present work, we attempted... -
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- Histochemical and Ultrastructural Studies of Hepatic Fibrogenesis; Its Initiation and the Effect of Dexamethasone in Rats
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Kim CJ, Park CI, Kim CS, Lee YB
- KMID: 692940
- Yonsei Med J.
- 1982 Dec;23(2):89-100.
- doi: 10.3349/ymj.1982.23.2.89
Intralobular fibrogenesis of the liver following hepatocellular damage has long been a controversial subject in regard to its initiation and prevention. To investigate the site of hepatic fibrogenesis and the... -
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- Changes of biomarkers with oral exposure to benzo(a)pyrene, phenanthrene and pyrene in rats
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Kang HG, Jeong SH, Cho MH, Cho JH
- KMID: 1106216
- J Vet Sci.
- 2007 Dec;8(4):361-368.
- doi: 10.4142/jvs.2007.8.4.361
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants present in air and food. Among PAHs, benzo(a)pyrene(BaP), phenanthrene (PH) and pyrene (PY) are considered to be important for their toxicity or... -
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- Effect of Fish Oil Diet on Activities of Lipogenic Enzymes and Glucose -6 -phosphatase in Rat Liver and Adipose
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Jung SE
- KMID: 1401868
- J Nurs Acad Soc.
- 1989 Dec;19(3):299-306.
In order to evaluate the effect of fish oil on lipid drogenase(G6PDH), malic enzyme (ME), glucose-6 -phosphatase (G6Pase) activities were measured in liver and adipose tissue of rats fed... -
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- Influence of Corticosteroids on the Hepatic Cell and Bile Secretion (1)
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Kim YH, Lee YB, Hong SS
- KMID: 687608
- Yonsei Med J.
- 1969 Jun;10(1):10-18.
- doi: 10.3349/ymj.1969.10.1.10
Daily administration of glucocorticoids for 10 days to dogs resulted in a significant increase in the hepatic bile secretion in response to secretory stimulants. The response of hepatic bile in... -
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- Protective effects of silymarin on fumonisin B1-induced hepatotoxicity in mice
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Sozmen M, Devrim AK, Tunca R, Bayezit M, Dag S, Essiz D
- KMID: 1737610
- J Vet Sci.
- 2014 Mar;15(1):51-60.
- doi: 10.4142/jvs.2014.15.1.51
The present study was conducted to investigate the effect of silymarin on experimental liver toxication induced by Fumonisin B1 (FB1) in BALB/c mice. The mice were divided into six groups... -
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- The Increase in Hepatic Uncoupling by Fenofibrate Contributes to a Decrease in Adipose Tissue in Obese Rats
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Park MK, Lee HJ, Hong SH, Choi SS, Yoo YH, Lee KI, Kim DK
- KMID: 1713174
- J Korean Med Sci.
- 2007 Apr;22(2):235-241.
- doi: 10.3346/jkms.2007.22.2.235
Fenofibrate is a drug that has been suggested to inhibit weight gain by increasing the catabolism of fatty acid in the hepatic mitochondria. We hypothesized that fenofibrate induces an increase... -
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- Repeated dose toxicity of alfa-cypermethrin in rats
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Manna S, Bhattacharyya D, Mandal TK, Das S
- KMID: 1099838
- J Vet Sci.
- 2004 Sep;5(3):241-245.
The present study was performed to investigate the subacute effect of alpha-cypermethrin (alpha-CP) in rats. Alfacypermethrin a synthetic pyrethroid insecticide, dissolved in dimethyl sulfoxide (DMSO) and oral LD50 was investigated... -
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