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Gestational hyperlipidemia and acute pancreatitis with underlying partial lipoprotein lipase deficiency and apolipoprotein E3/E2 genotype

Han DH, Moh IH, Kim DM, Ihm SH, Choi MG, Yoo HJ, Hong EG

We report the case of a patient who experienced extreme recurrent gestational hyperlipidemia. She was diagnosed with partial lipoprotein lipase (LPL) deficiency but without an associated LPL gene mutation in...
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Genetic predisposition in nonalcoholic fatty liver disease

Sookoian S, Pirola CJ

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease whose prevalence has reached global epidemic proportions. Although the disease is relatively benign in the early stages, when...
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Antiobesity activity of a sphingosine 1-phosphate analogue FTY720 observed in adipocytes and obese mouse model

Moon MH, Jeong JK, Lee JH, Park YG, Lee YJ, Seol JW, Park SY

  • KMID: 1506224
  • Exp Mol Med.
  • 2012 Oct;44(10):603-614.
Higher levels of body fat are associated with an increased risk for development numerous adverse health conditions. FTY720 is an immune modulator and a synthetic analogue of sphingosine 1-phosphate (S1P),...
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Nonalcoholic Fatty Liver Disease

Ko JS

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide, and is commonly associated with obesity. The spectrum of NAFLD ranges from simple steatosis to nonalcoholic steatohepatitis (NASH)...
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