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Advances in Fast Vessel-Wall Magnetic Resonance Imaging Using High-Density Coil Arrays

Yin X, Li N, Jia S, Zhang X, Li Y

Arteriosclerosis is the leading cause of stroke, with a fatality rate surpassing that of ischemic heart disease. High-resolution vessel wall magnetic resonance imaging is generally recognized as a non-invasive and...
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Biological Characteristics of Recombinant Arthrobotrys oligospora Chitinase AO-801

Gong S, Meng Q, Qiao J, Huang Y, Zhong W, Zhang G, Zhang K, Li N, Shang Y, Li Z, Cai X

Chitinase AO-801 is a hydrolase secreted by Arthrobotrys oligospora during nematode feeding, while its role remained elusive. This study analyzed the molecular characteristics of recombinant chitinase of Arthrobotrys oligospora (reAO-801)....
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The Associations of Family Functioning, General Well-Being,and Exercise with Mental Health among End-Stage RenalDisease Patients

Wang Q, Liu H, Ren Z, Xiong W, He M, Li N, Fan X, Guo X, Li X, Shi H, Zha S, Zhang X

Objective This study aims to explore the relationships of family functioning, general well-being, and exercise with psychological distress. Furthermore, we investigated the special roles of general well-being and exercise on the...
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Serial Frozen Fecal Microbiota Transplantation in the Treatment of Chronic Intestinal Pseudo-obstruction: A Preliminary Study

Gu L, Ding C, Tian H, Yang B, Zhang X, Hua Y, Zhu Y, Gong J, Zhu W, Li J, Li N

  • KMID: 2433530
  • J Neurogastroenterol Motil.
  • 2017 Apr;23(2):289-297.
  • doi: 10.5056/jnm16074
BACKGROUND/AIMS: Chronic intestinal pseudo-obstruction (CIPO) is a serious, life-threatening motility disorder that is often related to bacterial overgrowth. Fecal microbiota transplantation (FMT) results in restoration of the normal intestinal microbial...
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The Correlation between Thyrotropin and Dyslipidemia in a Population-based Study

Lu L, Wang B, Shan Z, Jiang F, Teng X, Chen Y, Lai Y, Wang J, Xue H, Wang S, Li C, Liu H, Li N, Yu J, Shi L, Hou X, Xing Q, Bai X, Teng W

This study investigated the relationship between serum thyrotrophin levels and dyslipidemia in subclinical hypothyroid and euthyroid subjects. A total of 110 subjects with subclinical hypothyroidism and 1,240 euthyroid subjects enrolled...
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Patient Response to Endoscopic Therapy for Gastroesophageal Varices Based on Endoscopic Ultrasound Findings

Tseng Y, Ma L, Luo T, Zeng X, Li F, Li N, Wei Y, Chen S

BACKGROUND/AIMS: Gastroesophageal variceal hemorrhage is a common complication of portal hypertension. Endoscopic therapy is currently recommended for preventing gastroesophageal variceal rebleed. However, the rate of variceal rebleed and its associated...
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Glucosamine induces cell death via proteasome inhibition in human ALVA41 prostate cancer cell

Liu BQ, Meng X, Li C, Gao YY, Li N, Niu XF, Guan Y, Wang HQ

Glucosamine, a naturally occurring amino monosaccharide, has been reported to play a role in the regulation of apoptosis more than half century. However the effect of glucosamine on tumor cells...
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Packaging of Rift Valley fever virus pseudoviruses and establishment of a neutralization assay method

Li Y, Zhao Y, Wang C, Zheng X, Wang H, Gai W, Jin H, Yan F, Qiu B, Gao Y, Li N, Yang S, Xia X

Rift Valley fever (RVF) is an acute, febrile zoonotic disease that is caused by the RVF virus (RVFV). RVF is mainly prevalent on the Arabian Peninsula, the African continent, and...
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Tissue Engineering with Compact Bone-Derived Cell Spheroids Enables Bone Formation around Transplanted Tooth

Matsumura N, Li X, Uchikawa-Kitaya E, Li N, Dong H, Chen K, Yoshizawa M, Kagami H

BACKGROUND: Although tooth transplantation is a desirable treatment option for congenital defects of permanent teeth in children, transplantation to a narrow alveolar ridge is not feasible. In this study, we...
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Effectiveness and Safety of Dabrafenib in the Treatment of 20 Chinese Children with BRAFV600E-Mutated Langerhans Cell Histiocytosis

Yang Y, Wang D, Cui L, Ma HH, Zhang L, Lian HY, Zhang Q, Zhao XX, Zhang LP, Zhao YZ, Li N, Wang TY, Li ZG, Zhang R

Purpose We sought to investigate the effectiveness and safety of dabrafenib in children with BRAFV600E-mutated Langerhans cell histiocytosis (LCH). Materials and Methods A retrospective analysis was performed on 20 children...
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Development and validation of a stromal-immune signature to predict prognosis in intrahepatic cholangiocarcinoma

Ye YH, Xin HY, Li JL, Li N, Pan SY, Chen L, Pan JY, Hu ZQ, Wang PC, Luo CB, Sun RQ, Fan J, Zhou J, Zhou ZJ, Zhou SL

Background: Intrahepatic cholangiocarcinoma (ICC) is a highly desmoplastic tumor with poor prognosis even after curative resection. We investigated the associations between the composition of the ICC stroma and immune cell...
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Berberine Prevents Intestinal Mucosal Barrier Damage During Early Phase of Sepsis in Rat through the Toll-Like Receptors Signaling Pathway

Li GX, Wang XM, Jiang T, Gong JF, Niu LY, Li N

Our previous study has shown berberine prevents damage to the intestinal mucosal barrier during early phase of sepsis in rat through mechanisms independent of the NOD-like receptors signaling pathway. In...
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Silencing of Fanconi Anemia Complementation Group F Exhibits Potent Chemosensitization of Mitomycin C Activity in Breast Cancer Cells

Yu J, Zhao L, Li Y, Li N, He M, Bai X, Yu Z, Zheng Z, Mi X, Wang E, Wei M

PURPOSE: Fanconi anemia complementation group F (FANCF) is a key factor to maintaining the function of Fanconi anaemia/BRCA (FA/BRCA) pathway, a DNA-damage response pathway. However, the functional role of FANCF...
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Overview of fuzuloparib in the treatment of ovarian cancer: background and future perspective

Li N, Liu Q, Tian Y, Wu L

Over the last decade, clinical trials using various poly ADP ribose polymerase (PARP) inhibitors on patients with ovarian cancer have shown promising results. The introduction of PARP inhibitors has changed...
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Cervical Spondylotic Myelopathy due to the Ochronotic Arthropathy of the Cervical Spine

Li N, Tian W, Yuan Q, He D

Ochronosis is a musculoskeletal manifestation of alkaptonuria, a rare hereditary metabolic disorder occurs due to the absence of homogentisic acid oxidase and leading to various systemic abnormalities related to deposition...
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Paip1 Indicated Poor Prognosis in Cervical Cancer and Promoted Cervical Carcinogenesis

Li N, Piao J, Wang X, Kim KY, Bae JY, Ren X, Lin Z

PURPOSE: This study was aimed to investigate the role of poly(A)-binding protein-interacting protein 1 (Paip1) in cervical carcinogenesis. MATERIALS AND METHODS: The expression of Paip1 in normal cervical epithelial tissues and...
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Erdheim-Chester Disease with Emperipolesis: A Unique Case Involving the Heart

Zhu P, Li N, Yu L, Miranda MN, Wang G, Duan Y

Histiocytosis is an uncommon disease characterized by excessive accumulation of histiocytes. Here, we report a rare case of non-Langerhans-cell histiocytosis in a 51-year-old woman who presented with severe symptoms of...
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Atorvastatin Pretreatment Ameliorates Mesenchymal Stem Cell Migration through miR-146a/CXCR4 Signaling

Li N, Guo XY, Zhou J, Yan XL, Yu FF

BACKGROUND: We previously found that atorvastatin (ATV) enhanced mesenchymal stem cells (MSCs) migration, by a yet unknown mechanism. CXC chemokine receptor 4 (CXCR4) is critical to cell migration and regulated by...
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Metformin Attenuates Liver Fat Content: Finding from Schizophrenia Patients with Olanzapine-induced Weight Gain

Wang L, Chen Y, Sui Yc, Tan Xq, Zhou Z, Li N, Xu Lp

Objective: This study was performed to evaluate the efficacy of metformin on liver fat content (LFC) in first episode schizophrenia patients with olanzapine-induced weight gain, and the relationship between the...
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AITC induces MRP1 expression by protecting against CS/CSE-mediated DJ-1 protein degradation via activation of the DJ-1/Nrf2 axis

Xu L, Wu J, Li N, Jiang C, Guo Y, Cao P, Wang D

The present study aimed to examine the effect of allyl isothiocyanate (AITC) on chronic obstructive pulmonary disease and to investigate whether upregulation of multidrug resistance-associated protein 1 (MRP1) associated with...
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