- Leukotrienes and Allergic Inflammation
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- KMID: 1969527
- Korean J Asthma Allergy Clin Immunol.
- 2012 Jun;32(2):67-72.
Leukotrienes (LTs) are important lipid mediators involved in allergic inflammation. The LT pathway is relatively steroid-resistant, which suggests the possibility that its blockade by alternative means may facilitate asthma management.... -
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- A Case of Pranlukast-Induced Anaphylactic Shock
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Kim S, Lee JM
- KMID: 2391048
- Allergy Asthma Immunol Res.
- 2016 May;8(3):276-278.
- doi: 10.4168/aair.2016.8.3.276
Leukotriene receptor antagonists, which are generally considered safe with a few adverse drug reactions, are increasingly used in the treatment of various allergic diseases, including asthma and allergic rhinitis. Although... -
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- MUC2/5AC Expression and Mucin Secretion through Leukotriene Receptor in Human Airway Epithelial Cells
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Kim YD, Lee JE, Bai CH, Seo YJ, Ye SB, Song SY
- KMID: 2276273
- Korean J Otolaryngol-Head Neck Surg.
- 2004 Nov;47(11):1115-1119.
BACKGROUND AND OBJECTIVES: Mucin gene expression and mucin production are highly increased during inflammatory airway disorders such as, asthma, chronic bronchitis and sinusitis. Cytokines, lipopolysaccharides and other inflammatory mediators are... -
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- Association of Leukotriene C4 Synthase Gene Polymorphism with Clinical Response to Montelukast in Childhood Asthma
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Shin KS, Kim YW
- KMID: 1855968
- Korean J Pediatr.
- 2005 Jul;48(7):766-771.
PURPOSE: Cysteinyl leukotrienes are important inflammatory mediators in the pathogenesis of asthma; therefore interruption of cysteinyl leukotrienes by leukotriene receptor antagonists improves clinical symptoms in the management of patients with... -
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- Chronic Spontaneous Urticaria: Pathogenesis and Treatment Considerations
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Kaplan AP
- KMID: 2421657
- Allergy Asthma Immunol Res.
- 2017 Nov;9(6):477-482.
- doi: 10.4168/aair.2017.9.6.477
The treatment of chronic spontaneous urticaria begins with antihistamines; however, the dose required typically exceeds that recommended for allergic rhinitis. Second-generation, relatively non-sedating H1-receptor blockers are typically employed up to... -
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- Protection of leukotriene receptor antagonist against aspirin-induced bronchospasm in asthmatics
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Park JS, Jang AS, Park SW, Lee YM, Uh ST, Kim YH, Cha JY, Park SM, Park CS
- KMID: 2260419
- Allergy Asthma Immunol Res.
- 2010 Jan;2(1):48-54.
- doi: 10.4168/aair.2010.2.1.48
PURPOSE: Leukotriene receptor antagonists (LTRAs) are used to treat aspirin-intolerant asthma (AIA); however, the protective effects of long-term LTRA administration against aspirin-induced bronchospasm have not been evaluated. OBJECTIVES: We investigated the... -
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- The Effects of Leukotriene Receptor Antagonist on Nasal Mucous Membrane in Allergic Model of Guinea Pigs
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Yu MS, Lee JH, Park JK, Lee JD, Kim DW, Lee BD, Chang HS, Cho JS
- KMID: 2115454
- Korean J Otolaryngol-Head Neck Surg.
- 2003 Dec;46(12):1028-1034.
BACKGROUND AND OBJECTIVES: The leukotriene (LT) receptor antagonist is subject to an on-going study of allergic rhinitis, nasal polyposis and chronic paranasal sinusitis. This study was designed to evaluate the... -
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- Esophageal Mast Cell Infiltration in a 32-Year-Old Woman with Noncardiac Chest Pain
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Lee K, Kwon HJ, Kim IY, Yoo KH, Lee S, Min YW, Rhee PL
- KMID: 2382357
- Gut Liver.
- 2016 Jan;10(1):152-155.
- doi: 10.5009/gnl14294
Noncardiac chest pain (NCCP) is one of the most common esophageal symptoms and lacks a clearly defined mechanism. The most common cause of NCCP is gastroesophageal reflux disease (GERD). One... -
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- The role of leukotriene modifier in pediatric allergic disease
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Choi BS, Sohn MH, Kim KE
- KMID: 2218654
- Allergy Asthma Respir Dis.
- 2015 Jul;3(4):255-260.
- doi: 10.4168/aard.2015.3.4.255
Leukotriene (LT) modifiers are composed of leukotriene receptor antagonists and 5-lipoxygenase inhibitors. LTs, C4, D4, and E4 are collectively termed cysteinyl LTs and best are the characterized receptors for cysLTs... -
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- Successful Remission of Recurrent Anaphylaxis after Omalizumab Administration in a Patient with Systemic Mastocytosis
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Moon H, Jang HJ, Lee CG, Kim YC, Yoo SH, Lee DS, Kang HR
- KMID: 2435039
- Korean J Med.
- 2018 Feb;93(1):68-73.
- doi: 10.3904/kjm.2018.93.1.68
Mastocytosis is a disorder characterized by abnormal mast cell proliferation and accumulation in one or more tissues. It presents in two major variants: cutaneous mastocytosis and systemic mastocytosis. Because the... -
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- The Effect of Montelukast in the Treatment of Atopic Dermatitis through the SCORAD Index
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Lee YK, Kim YH, Kim KH, Lee CW
- KMID: 2087907
- Korean J Dermatol.
- 2008 Jan;46(1):34-39.
BACKGROUND: Atopic dermatitis (AD) is a chronic, relapsing, inflammatory skin disease, with genetic and environmental background. The pathogenesis is complex, and although the dermatitis fades during childhood in most cases,... -
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- Survey on the Current Status of Asthma Maintenance Therapy and the Impact of Asthma on Children and Family Life
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Kwak IK, Lim KH, Kim YH, Kong DY, Pyun BY, Lee HR
- KMID: 2314403
- Pediatr Allergy Respir Dis.
- 2005 Dec;15(4):415-426.
PURPOSE: In spite of the development of asthma management guidelines, there are discrepancies between the guidelines and real management. We surveyed the insights and the real management of asthma to... -
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- Update on Recent Advances in the Management of Aspirin Exacerbated Respiratory Disease
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Palikhe NS, Kim JH, Park HS
- KMID: 1777085
- Yonsei Med J.
- 2009 Dec;50(6):744-750.
- doi: 10.3349/ymj.2009.50.6.744
Aspirin intolerant asthma (AIA) is frequently characterized as an aspirin (ASA)-exacerbated respiratory disease (AERD). It is a clinical syndrome associated with chronic severe inflammation in the upper and lower airways... -
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- Effects of Interleukin-13 and Montelukast on the Expression of Zonula Occludens-1 in Human Podocytes
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Park SJ, Saleem MA, Nam JA, Ha TS, Shin JI
- KMID: 2070020
- Yonsei Med J.
- 2015 Mar;56(2):426-432.
- doi: 10.3349/ymj.2015.56.2.426
PURPOSE: The aim of this study was to investigate whether pathologic changes in zonula occludens-1 (ZO-1) are induced by interleukin-13 (IL-13) in the experimental minimal-change nephrotic syndrome (MCNS) model and... -
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- Eosinophilic Esophagitis
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Park H
- KMID: 782931
- Korean J Gastroenterol.
- 2007 Nov;50(5):286-291.
Eosinophilic esophagitis (EE) is characterized by eosinophilic infiltration of the esophageal wall including mucosa, submucosa, and muscle proper. EE is a condition involving both pediatrics and adults. Patients with EE... -
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- Management of Rhinitis: Allergic and Non-Allergic
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Tran NP, Vickery J, Blaiss MS
- KMID: 1803320
- Allergy Asthma Immunol Res.
- 2011 Jul;3(3):148-156.
- doi: 10.4168/aair.2011.3.3.148
Rhinitis is a global problem and is defined as the presence of at least one of the following: congestion, rhinorrhea, sneezing, nasal itching, and nasal obstruction. The two major classifications... -
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- Treatment of Chronic Spontaneous Urticaria
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Kaplan AP
- KMID: 2167015
- Allergy Asthma Immunol Res.
- 2012 Nov;4(6):326-331.
- doi: 10.4168/aair.2012.4.6.326
Chronic spontaneous urticaria is defined as persistent symptoms of urticaria for 6 weeks or more. It is associated with autoimmunity in approximately 45 percent of patients. Therapy is often difficult... -
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- Non-comparative, multicenter trial to assess the additional responses of Accolate (Zafirlukast) in persistent bronchial asthma
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Park JW, Cho YJ, Yoon HJ, Park HS, Choi IS, Choi BW, Park CS, Min KU, Rhee YK, Kim NS, Hong CS
- KMID: 2285948
- J Asthma Allergy Clin Immunol.
- 2001 Jun;21(3):552-560.
BACKGROUND AND OBJECTIVE: Accolate, one of the cysteinyl leukotriene receptor antagonists, have anti-inflammatory and bronchodilating effects. The clinical indications for LT antagonist are not yet in consensus. We performed a... -
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- The efficacy and safety of Montelukast sodium in the prevention of bronchopulmonary dysplasia
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Kim SB, Lee JH, Lee J, Shin SH, Eun HS, Lee SM, Sohn JA, Kim HS, Choi BM, Park MS, Park KI, Namgung R, Park MS
- KMID: 2284516
- Korean J Pediatr.
- 2015 Sep;58(9):347-353.
- doi: 10.3345/kjp.2015.58.9.347
PURPOSE: The purpose of this study was to evaluate the efficacy and safety of Montelukast sodium in the prevention of bronchopulmonarydysplasia (BPD). METHODS: The Interventional study was designed as a multicenter,... -
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- Effect of Inhibitor of TNF-alpha and Oxatomide on Experimental Immune Mediated Otitis Media with Effusion
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Auo HJ, Park YS, Jeon EJ, Yeo SW, Chang KH, Lee SK
- KMID: 2276167
- Korean J Otolaryngol-Head Neck Surg.
- 2004 Jun;47(6):507-514.
BACKGROUND AND OBJECTIVES: Local immune response, one of the pathogenesis of middle ear effusion (MEE) is associated with the development and persistence of effusion in the middle ear cavity and... -
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