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Juvenile systemic sclerosis

Kim YD

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Cerebral small vessel vasculitis triggered by neurotoxoplasma-related ETosis: histological and immunofluorescence observation of a case

Gaggero G, Bertolotto M, Verzola D, Ferro J, Fiaschi P

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Machine learning models with time-series clinical features to predict radiographic progression in patients with ankylosing spondylitis

Koo BS, Jang M, Oh JS, Shin K, Lee S, Joo KB, Kim N, Kim TH

Objective: Ankylosing spondylitis (AS) is chronic inflammatory arthritis causing structural damage and radiographic progression to the spine due to repeated and continuous inflammation over a long period. This study establishes...
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Medical treatment of osteoarthritis: botanical pharmacologic aspect

Park J, Lee SW

Osteoarthritis (OA) is the most common form of arthritis, and its prevalence is expected to further increase as our society ages. Despite many approaches to cure OA, no drugs are currently...
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Successful treatment of hemophagocytic lymphohistiocytosis in a patient with systemic lupus erythematosus with ruxolitinib: a case report

Jung JI, Kim JY, Kim MH, Park JK, Lee EY, Lee EB, Park JW

Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening hematological disorder characterized by uncontrolled activation of CD8+ T and natural killer cells, leading to a cytokine storm and severe organ dysfunction. Although...
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Real-world effectiveness of a single conventional diseasemodifying anti-rheumatic drug (cDMARD) plus an anti-TNF agent versus multiple cDMARDs in rheumatoid arthritis: a prospective observational study

So MW, Kim SH, Kim DW, Sung YK, Choe JY, Lee SI, Hur JW, Lee HS, Lee SH, Kim JR

Objective: The objective of this prospective, observational multicenter study (NCT03264703) was to compare the effectiveness of single conventional disease-modifying anti-rheumatic drug (cDMARD) plus anti-tumor necrosis factor (TNF) therapy versus multiple...
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Piriformis syndrome as an overlooked cause of pain in a patient with axial spondyloarthritis: a case report

Tezcan EA, Erol K, Gezer IA

Piriformis syndrome is a neuromuscular disorder characterized by hip, buttock, and leg pain. Axial spondyloarthritis is a rheumatic disease primarily affecting the sacroiliac joint and the spine. Due to their...
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Lupus nephritis presenting with massive ascites and pleural effusion (pseudo-pseudo Meigs’ syndrome)

Deniz R, Hacımurtazaoğlu-Demir G, Karaalioğlu B, Özgür DS, Akkuzu G, Yıldırım F, Bes C

The triad of ascites, pleural effusion, and elevated cancer antigen-125 (CA-125) levels in the absence of ovarian malignancy in systemic lupus erythematosus patients is specifically named pseudo-pseudo Meigs’ syndrome (PPMS)...
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Urate-lowering therapy is associated with a reduced risk of arrhythmias: a systematic review and meta-analysis

Waitayangkoon P, Leesutipornchai T, Techasatian W, Aiumtrakul N, Tanariyakul M, Arayangkool C, Kanthajan T, Nagamine T, Kewcharoen J

Objective: While urate-lowering therapy (ULT) is linked to increased cardioprotective benefits on primary prevention of cardiovascular events such myocardial infarction or heart failure, little is known regarding their effects on...
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Effect of recombinant human bone morphogenetic protein-2 and osteoprotegerin-Fc in MC3T3-E1 cells

Kim SH, Choi HJ, Lee SM, Yoon DS, Son CN

Objective: We compared the osteoblastogenesis by serially administrating recombinant human bone morphogenetic protein-2 (rhBMP-2) and osteoprotegerin-immunoglobulin Fc segment complex (OPG-Fc). Methods: The MC3T3-E1 preosteoblast cell line was differentiated for 1, 3,...
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