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What’s new in neuromuscular pathology 2022: myopathy updates and gene therapies

Cai C

This compilation of new changes in the diagnosis and treatment of muscle and nerve disease is extracted from the latest publications from the European Neuromuscular Centre International workshops, FDA.gov and...
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A standardized pathology report for gastric cancer: 2nd edition

Park YS, Kook MC, Kim Bh, Lee HS, Kang DW, Gu MJ, Shin OR, Choi Y, Lee W, Kim H, Song IH, Kim KM, Kim HS, Kang G, Park DY, Jin SY, Kim JM, Choi YJ, Chang HK, Ahn S, Chang MS, Han SH, Kwak Y, Seo AN, Lee SH, Cho MY, The Gastrointestinal Pathology Study Group of the Korean Society of Pathologists

The first edition of ‘A Standardized Pathology Report for Gastric Cancer’ was initiated by the Gastrointestinal Pathology Study Group of the Korean Society of Pathologists and published 17 years ago....
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Single-cell and spatial sequencing application in pathology

Kim YS, Choi J, Lee SH

Traditionally, diagnostic pathology uses histology representing structural alterations in a disease’s cells and tissues. In many cases, however, it is supplemented by other morphology-based methods such as immunohistochemistry and fluorescent...
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Metallic implant-associated lymphoma: ALK-negative anaplastic large cell lymphoma associated with total knee replacement arthroplasty

Go JH

Metallic implant-associated lymphomas are extremely rare. Only seven cases have been reported in association with knee joint arthroplasty, and all tumors were large B-cell lymphomas. This report is the first...
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Inflammatory bowel disease–associated intestinal fibrosis

Park JM, Kim J, Lee YJ, Bae SU, Lee HW

Fibrosis is characterized by a proliferation of fibroblasts and excessive extracellular matrix following chronic inflammation, and this replacement of organ tissue with fibrotic tissue causes a loss of function. Inflammatory...
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Perspectives on single-nucleus RNA sequencing in different cell types and tissues

Kim N, Kang H, Jo A, Yoo SA, Lee HO

Single-cell RNA sequencing has become a powerful and essential tool for delineating cellular diversity in normal tissues and alterations in disease states. For certain cell types and conditions, there are...
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The proteomic landscape shows oncologic relevance in cystitis glandularis

Kim JY, Han D, Kim H, Jung M, Ryu HS

Background: The relationship between cystitis glandularis (CG) and bladder malignancy remains unclear. Methods: We identified the oncologic significance of CG at the molecular level using liquid chromatography-tandem mass spectrometry-based proteomic...
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Infections and immunity: associations with obesity and related metabolic disorders

Ray A, Bonorden MJL, Pandit R, Nkhata KJ, Bishayee A

About one-fourth of the global population is either overweight or obese, both of which increase the risk of insulin resistance, cardiovascular diseases, and infections. In obesity, both immune cells and...
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