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Genetic variation occurs on many different scales, ranging from gross alteration in human chromosomes to single nucleotide changes. Approximately 99.5% of the human genome sequence is identical among humans. The...
Osteoarthritis (OA) is a slowly progressive degenerative disorder of weight-bearing joints, mainly characterized by joint pain and functional limitation. Current pharmacological treatment of OA mainly focuses on the alleviation of...
Mesenchymal stem cells are stem cells originated from the mesoderm have the capacity to differentiate into cells of connective tissue lineages, including bone, fat, cartilage and muscle. Nontraumatic osteonecrosis of...
It is well known that mesenchymal stem cell originated from adjacent periosteum and bone marrow play an important role in bone regeneration process such as fracture healing, bone defect healing...
PURPOSE: This study was performed to examine any histopathological changes occurring in the growth plate when the rats were subjected to be deprived of normal weight bearing using the hindlimb...
Nam JS, Nidi S, Sharma AR, Lee JK, Kwon SC, Chang JD, Lee SS
KMID: 1455842
J Korean Orthop Res Soc.
2010 Jun;13(1):35-42.
PURPOSE: The intracellular mechanisms that lead to periprosthetic osteolysis including impaired bone forming activity of osteoblast remain incompletely characterized. To determine the possibility that Ti-particles play a role to regulate...