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Epstein-Barr Virus Related Polymorphic Posttransplantation Lymphoproliferative Disease in a Patient with Latent Infection of JC Virus

Bin CH, Park MS

  • KMID: 1966511
  • J Korean Neurol Assoc.
  • 2012 May;30(2):136-140.
Posttransplantation lymphoproliferative disease (PTLD) is an important form of posttransplant malignancy and is typically associated with Epstein-Barr virus (EBV). Progressive multifocal leukoencephalopathy (PML) is a demyelination disease caused by infection...
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Progressive Multifocal Leukoencephalopathy Presenting as Viral Encephalitis in a Healthy Adult

Na JY, Lee WG, Kim K

  • KMID: 1966529
  • J Korean Neurol Assoc.
  • 2012 Aug;30(3):218-221.
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system caused by the human polyomavirus JC virus. PML mainly occurs in immunocompromised patients. A 36-year-old man with...
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Progressive Multifocal Leukoencephalopathy in the Immunocompromised Patients - 3 Cases Report

Shim MK, Kim JH, Park CS, Kim HS, Choi YD, Lee MC

  • KMID: 1521633
  • Korean J Pathol.
  • 2007 Oct;41(5):358-361.
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease resulting from infection of oligodendrocytes with JC virus. PML was a rare disease, but nowadays not uncommon as AIDS prevailed. Histopathologic features...
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Detection of JC Virus in the Brains of Korean Glioblastoma Multiforme Patients

Han JW, Kim BH, Jeon YC, Ahn SK, Kim YS, Ahn MS

  • KMID: 1904997
  • J Korean Neurosurg Soc.
  • 2004 Sep;36(3):224-228.
OBJECTIVE: The ubiquitous human polyomavirus, JC virus(JCV) is the etiologic agent of the fatal demyelinating central nervous system(CNS) disease, progressive multifocal leukoencephalopathy(PML). Recent studies have reported the detection of the...
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Detection of JC Virus T-Ag in Early Gastric Cancer

Jang EJ, Jang JS, Kim JH, Bae HI, Suh IS

  • KMID: 2277552
  • Korean J Pathol.
  • 2010 Oct;44(5):456-461.
BACKGROUND: JC virus (JCV) is a polyomavirus that commonly infects humans and can cause progressive multifocal leukoencephalopathy in immunocompromised patients. Recently, many reports have documented detection of JCV in gastrointestinal...
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Progressive Multifocal Leukoencephalopathy in a Patient With Myasthenia Gravis and Thymoma

Kang HH, Park JH, Lee MJ, Cho J, Suh YL, Lee SJ, Min JH, Kim BJ, Han SG

  • KMID: 2191526
  • J Korean Neurol Assoc.
  • 2012 Nov;30(4):312-315.
Progressive multifocal leukoencephalopathy (PML) is a rare and fatal disease caused by JC virus. We report a case of PML which developed in a 61-year-old female patient with myasthenia gravis...
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A Case of Immune Reconstitution Inflammatory Syndrome in AIDS-related Progressive Multifocal Leukoencephalopathy after Antiretroviral Therapy

Ju SH, Kim TH, Na JS, Song HS, Yu IK, Yoon HJ

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system due to JC virus. In acquired immunodeficiency syndrome (AIDS) patients, JC virus infects myelin-producing oligodendrocytes causing a...
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Viruria in Adult Hemorrhagic Cystitis Patients Following Allogeneic Hematopoietic Stem Cell Transplantation and Implication of Antiviral Treatment

Kim SY, Lee JW, Lee KM, Cho BS, Eom KS, Kim YJ, Lee S, Min CK, Kim HJ, Cho SG, Kim DW, Min WS, Kim CC

BACKGROUND: Viruria is frequently detected in patients who have had hemorrhagic cystitis (HC) following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Urinary viruses, especially BK virus, have been suggested as a...
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Association of Polyomaviruria with Hemorrhagic Cystitis in Recipients of Bone Marrow Transplants

Park MJ, Kang HJ, Shin DH, Lee KM, Lee DG, Choi JH, Kim CC

  • KMID: 2225981
  • Korean J Clin Pathol.
  • 2000 Dec;20(6):570-575.
BACKGROUND: Hemorrhagic cystitis(HC), a common complication of bone marrow transplantation(BMT), is known to be associated with toxic metabolites of chemotherapy drugs or reactivation of primary virus infections. In this study,...
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Polyomavirus-associated Nephropathy after Renal Transplantation

Park SB, Ahn HJ, Kim YS, Cho WH, Kim HC

  • KMID: 2003577
  • J Korean Soc Transplant.
  • 2006 Jun;20(1):25-34.
The first clinical infections with polyomavirus (PV) were demonstrated in 1971, when BK virus was isolated from the urine after a kidney transplant recipient and JC virus from the brain...
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A report of seven cases of progressive multifocal leukoencephalopathy in patients with acquired immune deficiency syndrome

Kwak DM, Jeong H, Park SM, Cha HH, Jung JY, Bang JH, Shin HS

  • KMID: 2081802
  • Korean J Med.
  • 2010 Jun;78(6):771-775.
Secondary opportunistic central nervous system infections occur in approximately one-third of patients with acquired immune deficiency syndrome. With the introduction of highly active antiretroviral therapy, the number of opportunistic infection...
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Systematic review of the published data on the worldwide prevalence of John Cunningham virus in patients with multiple sclerosis and neuromyelitis optica

Paz SP, Branco L, Pereira MA, Spessotto , Fragoso YD

OBJECTIVES: John Cunningham virus (JCV) is a polyoma virus that infects humans, mainly in childhood or adolescence, and presents no symptomatic manifestations. JCV can cause progressive multifocal leukoencephalopathy (PML) in...
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Polyomavirus Activation in Pediatric Patients with Hemorrhagic Cystitis Following Hematopoietic Stem Cell Transplantation

Han SH, Noh OK, Lee SW, Park SJ, Jung HJ, Park JE

  • KMID: 2049277
  • Clin Pediatr Hematol Oncol.
  • 2012 Oct;19(2):92-99.
BACKGROUND: Reactivation of the polyomavirus and the use of conditioning regimen may be the causes of hemorrhagic cystitis (HC) following hematopoietic stem cell transplantation (HSCT). However, there are only a...
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Progressive Multifocal Leukoencephalopathy after Ibrutinib Therapy for Chronic Lymphocytic Leukemia

Lutz M, Schulze AB, Rebber E, Wiebe S, Zoubi T, Grauer OM, Keßler T, Kerkhoff A, Lenz G, Berdel WE

Progressive multifocal leukoencephalopathy (PML) is a devastating neurological disease observed nearly exclusively in immunocompromised patients. Recently, the introduction of monoclonal antibodies significantly inhibiting the immune system such as rituximab has...
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High Seroprevalence and Index of Anti-John-Cunningham Virus Antibodies in Korean Patients with Multiple Sclerosis

Kim SH, Kim Y, Jung JY, Park NY, Jang H, Hyun JW, Kim HJ

BACKGROUND AND PURPOSE: The anti-John-Cunningham virus (JCV)-antibody serostatus and index are used in the risk stratification of progressive multifocal leukoencephalopathy (PML) in multiple sclerosis (MS) patients treated with natalizumab. However,...
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