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Effects of oral glucose ingestion on plasma amylin concentration in diabetic and nondiabetic humans

Lee IK, Park KY, Lee HW

  • KMID: 1700067
  • J Korean Diabetes Assoc.
  • 1993 Sep;17(3):259-265.
No abstract available.
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Immunocytochemical Expression of Amylin in Pancreatic Islets of Man, Rabbit and Guinea Pig

Kim SG, Kim YH, Cha JH, Kim J, Jung JW

  • KMID: 2224620
  • Korean J Anat.
  • 1997 Aug;30(4):411-420.
A putative polypeptide hormone identified as amylin[islet amyloid polypeptide] is synthesized and co-localized with insulin in B cells of pancreatic islets in several animal species including man. However, there is...
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Novel Molecules Regulating Energy Homeostasis: Physiology and Regulation by Macronutrient Intake and Weight Loss

Gavrieli A, Mantzoros

Excess energy intake, without a compensatory increase of energy expenditure, leads to obesity. Several molecules are involved in energy homeostasis regulation and new ones are being discovered constantly. Appetite regulating...
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Diabetes-related Amylin Dyshomeostasis: a Contributing Factor to Cerebrovascular Pathology and Dementia

Ly H, Despa F

Type 2 diabetes (T2D) increases the risk for cerebrovascular disease (CVD) and dementia. The underlying molecular mechanisms remain elusive, which hampers the development of treatment or/and effective prevention strategies. Recent...
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Leptin, Neuropeptide Y and Islet Amyloid Polypeptide Levels in Obese Children

Choi MS, Jee SH, Kim EY, Moon KR

  • KMID: 2315337
  • Pediatr Gastroenterol Hepatol Nutr.
  • 2012 Sep;15(3):166-174.
PURPOSE: The aim of this study was to compare serum leptin, neuropeptide Y (NPY), and islet amyloid polypeptide (amylin) levels in obese and normal weight children, and to investigate their...
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Computational Approach for Protein Structure Prediction

Venkatesan A, Gopal J, Candavelou M, Gollapalli S, Karthikeyan K

OBJECTIVES: To predict the structure of protein, which dictates the function it performs, a newly designed algorithm is developed which blends the concept of self-organization and the genetic algorithm. METHODS: Among...
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Amylin Analogue in the Treatment of Obesity

Kim CS

  • KMID: 2270826
  • Korean J Obes.
  • 2010 Jun;19(2):39-47.
Obesity is now the major contributor to cardiovascular disease, diabetes mellitus, sleep apnea, musculoskeletal disorders and certain cancers, as well as many psychosocial disorders. The primary management of obesity is...
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Novel Therapies for Type 2 Diabetes Mellitus

Ko JM

  • KMID: 1819674
  • J Korean Soc Pediatr Endocrinol.
  • 2009 Jun;14(1):11-18.
Type 2 diabetes mellitus (T2DM) is a progressive disorder caused by a combination of insulin resistance and betacell dysfunction. The role of new hormones and systems in maintaining blood glucose...
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New and emerging drugs in type 2 diabetes

Park IB

  • KMID: 2256406
  • Korean J Med.
  • 2007 May;72(5):446-450.
Recent advances in understanding insulin secretion, action and signaling have led to the development of new pharmacological agents. Several new emerging drugs and drug classes for the management of diabetes...
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Clinical Characteristics of S20G Mutation of Amylin Gene in Korean Type 2 Diabetic Patients

Cho YM, Kim M, Lee YY, Moon MK, Park KS, Kim SY, Lee HK

  • KMID: 2008280
  • J Korean Diabetes Assoc.
  • 2002 Oct;26(5):377-382.
BACKGROUND: Islet amyloid deposition, which is mainly composed of amylin, is a characteristic pathological finding in patients with type 2 diabetes mellitus. A missense mutation of amylin at amino acid...
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Delayed Response of Amylin Levels after an Oral Glucose Challenge in Children with Prader-Willi Syndrome

Lee HJ, Choe YH, Lee JH, Sohn YB, Kim SJ, Park SW, Son JS, Kim SW, Jin DK

PURPOSE: Amylin secretion is increased parallel to insulin in obese subjects. Despite their marked obesity, a state of relative hypoinsulinemia occurs in children with Prader-Willi syndrome (PWS). Based on the...
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