- Introns: The Functional Benefits of Introns in Genomes
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Jo BS, Choi SS
- KMID: 2166525
- Genomics Inform.
- 2015 Dec;13(4):112-118.
- doi: 10.5808/GI.2015.13.4.112
The intron has been a big biological mystery since it was first discovered in several aspects. First, all of the completely sequenced eukaryotes harbor introns in the genomic structure, whereas... -
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- Comparative Evaluation of Intron Prediction Methods and Detection of Plant Genome Annotation Using Intron Length Distributions
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Yang L, Cho HG
- KMID: 2053286
- Genomics Inform.
- 2012 Mar;10(1):58-64.
- doi: 10.5808/GI.2012.10.1.58
Intron prediction is an important problem of the constantly updated genome annotation. Using two model plant (rice and Arabidopsis) genomes, we compared two well-known intron prediction tools: the Blast-Like Alignment... -
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- Enrichment of rare alleles within epigenetic chromatin marks in the first intron
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Jo SS, Choi SS
- KMID: 2447799
- Genomics Inform.
- 2019 Mar;17(1):e9.
- doi: 10.5808/GI.2019.17.1.e9
In previous studies, we demonstrated that some sites in the first intron likely regulate gene expression. In the present work, we sought to further confirm the functional relevance of first... -
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- A case of X-linked agammaglobulinemia with deletion of introns 15-18 of Btk gene mediated by Alu-Alu recombination
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Lee HJ, Ko JS, Kwon SS, Yoo JH, Min JK
- KMID: 2252751
- Korean J Med.
- 2003 Nov;65(Suppl 3):S798-S804.
X-linked agammaglobulinemia (XLA) is characterized by early onset of recurrent bacterial infection, markedly reduced levels of all major classes of immunoglobulins in the serum and few mature B cells in... -
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- Mitochondria and Aging
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Yoo HJ
- KMID: 2338151
- J Korean Geriatr Soc.
- 1998 Jun;2(1):1-7.
Mitochondrion has an important role in energy production in the cell. The importance has caused several workers to investigate its DNA and the expression of its genes during aging. Mitochondrial... -
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- Genomic Organization of ancop Gene for alpha-COP Homolog from Aspergillus nidulans
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Lee HH, Chae SK, Kim JY, Maeng PJ, Park HM
- KMID: 2312327
- Mycobiology.
- 2000 Dec;28(4):171-176.
We have cloned a alpha-COP homolog, ancop, from Aspergillus nidulans by colony hybridization of chromosome specific library using alpha-COP homologous fragment as a probe. The probe DNA was amplified with... -
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- Analysis of Complete Exons and Flanking Introns of ABO Gene in Korean B(3) Blood Donors
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Lee SG, Cho D, Jeon MJ, Song JW, Shin MG, Shin JH, Suh SP, Ryang DW
- KMID: 2254107
- Korean J Blood Transfus.
- 2006 Dec;17(2):97-105.
BACKGROUND: There have been several studies aimed at determining the presence of the B(3) specific alleles in Korean B(3) blood donors. However, in these samples, only consensus exons 6 and... -
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- Cloning and Characterization of a Novel Laccase Gene, fvlac7, Based on the Genomic Sequence of Flammulina velutipes
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Kim JK, Lim SH, Kang HW
- KMID: 2312683
- Mycobiology.
- 2013 Mar;41(1):37-41.
Laccases (EC 1.10.3.2) are copper-containing polyphenol oxidases found in white-rot fungi. Here, we report the cloning and analysis of the nucleotide sequence of a new laccase gene, fvlac7, based on... -
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- Cloning and Sequence Analysis of the Cellobiohydrolase I Genes from Some Basidiomycetes
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Chukeatirote E, Maharachchikumbura SSN, Wongkham S, Sysouphanthong P, Phookamsak R, Hyde KD
- KMID: 2052898
- Mycobiology.
- 2012 Jun;40(2):107-110.
- doi: 10.5941/MYCO.2012.40.2.107
Genes encoding the cellobiohydrolase enzyme (CBHI), designated as cbhI, were isolated from the basidiomycetes Auricularia fuscosuccinea, Pleurotus giganteus, P. eryngii, P. ostreatus, and P. sajor-caju. Initially, the fungal genomic DNA... -
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- Molecular Analysis of the UGT1A1 Gene in Korean Patients with Crigler-Najjar Syndrome Type II
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Ko JS, Chang JY, Moon JS, Yang HR, Seo JK
- KMID: 2315463
- Pediatr Gastroenterol Hepatol Nutr.
- 2014 Mar;17(1):37-40.
PURPOSE: Crigler-Najjar syndrome type II (CN-2) is characterized by moderate non-hemolytic unconjugated hyperbilirubinemia as a result of severe deficiency of bilirubin uridine diphosphate-glucuronosyltransferase (UGT1A1). The study investigated the mutation spectrum... -
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- Single Nucleotide Polymorphisms of a 16 kb Region on Human Chromosome 11p15.5 that Includes the H19 Gene
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Park MH, Ku HJ, Lee HJ, Kim KJ, Park C, Oh B, Kimm KC, Lee JY
- KMID: 1572676
- Genomics Inform.
- 2005 Sep;3(3):74-79.
The H19 gene, located at human chromosome 11p15.5, is imprinted in most normal human tissues. However, imprinting is often lost in tumors suggesting H19 is a putative tumor suppressor. We... -
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- Characterization of a Point Mutation in the First Intron of Bruton's Tyrosine Kinase ( Btk ) Gene
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Jo EK, Song CH, Song YJ, Min DL, Kim HJ, Lim K, Shong MH, Lee JH, Kim JS, Park JK
- KMID: 1646429
- Korean J Immunol.
- 2000 Dec;22(4):197-205.
No abstract available. -
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- Cloning and Expression Analysis of Phenylalanine Ammonia-Lyase Gene in the Mycelium and Fruit Body of the Edible Mushroom Flammulina velutipes
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Yun YH, Koo JS, Kim SH, Kong WS
- KMID: 2312830
- Mycobiology.
- 2015 Sep;43(3):327-332.
- doi: 10.5941/MYCO.2015.43.3.327
Phenylalanine ammonia-lyase (PAL) gene is known to be expressed in plants, and is involved in the differentiation, growth and synthesis of secondary metabolites. However, its expression in fungi remains to... -
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- Publicly Available Single Nucleotide Polymorphisms in Genes Possibly Susceptible to Antiepileptic Drug Resistance in Healthy Koreans
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Kim MK, Choi KH, Nam TS, Kim JT, Choi SM, Park MS, Kim BC, Cho KH
- KMID: 2065719
- J Korean Neurol Assoc.
- 2010 May;28(2):85-90.
BACKGROUND: The completion of the human genome project means that a high-quality reference sequence of the gene-rich portion of the human genome is now available. However, the strong influence of... -
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- Mutation Analysis of PIG-A Gene in Korean Patients with Paroxysmal Nocturnal Hemoglobinuria
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Yoon JH, Cho HI, Park SS, Chang YH
- KMID: 2083413
- Korean J Hematol.
- 2000 May;35(2):143-149.
BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is caused by deficient biosynthesis of the glycosylphosphatidylinositol (GPI) anchor in hemopoietic stem cells. Mutation of phosphatidyl inositol glycan class A (PIG-A) gene, an X-linked... -
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- The cis-AB01 Allele Originated From the A105 Allele, and not From the A102 Allele
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Yang SJ, Won EJ, Cho D, Shin MG, Ryang DW
- KMID: 2363197
- Ann Lab Med.
- 2015 Mar;35(2):279-280.
- doi: 10.3343/alm.2015.35.2.279
No abstract available. -
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- Cloning and Molecular Characterization of beta-1,3-Glucan Synthase from Sparassis crispa
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Yang YH, Kang HW, Ro HS
- KMID: 2312740
- Mycobiology.
- 2014 Jun;42(2):167-173.
A beta-glucan synthase gene was isolated from the genomic DNA of polypore mushroom Sparassis crispa, which reportedly produces unusually high amount of soluble beta-1,3-glucan (beta-glucan). Sequencing and subsequent open reading... -
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- Genomic Organization of ht eGene for Human Mig Chemokine
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Lee HH, Park KS
- KMID: 1557236
- Korean J Immunol.
- 1998 Dec;20(4):365-373.
"Mig is a gamma interferon-inducible T cell chemoattractant that is a member of the chemokine family of cytokines. In order to gain a better understanding of the molecular mechanisms that... -
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- Complete Sequencing of the ABO Alleles of the Common ABO Group and Rare ABO Subgroups in Koreans
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Won EJ, Park G, Cho D, Lim AH, Kwon SY, Song HR, Kweon SS, Shin MG, Cho NS, Ryang DW
- KMID: 1440716
- Korean J Blood Transfus.
- 2012 Apr;23(1):1-12.
BACKGROUND: Complete sequencing, except for intron 1, of the ABO allele in some populations has been reported. However, so far, one report on complete sequencing of the ABO gene in... -
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- Characterization of Mutations in Bruton's Tyrosine Kinase(Btk)Gene from Unrelated 3 X-linked Agammaglobulinemia(XLA) Families in Korea
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Song CH, Jo EK, Park JK, Kim JS, Hong SJ, Lee JH
- KMID: 2335593
- J Korean Pediatr Soc.
- 2002 Mar;45(3):302-310.
PURPOSE: X-linked agammaglobulinemia(XLA) is an immunodeficiency caused by abnormalities in Bruton's tyrosine kinase(Btk), and is characterized by a deficiency of peripheral blood B cells. We studied cytoplasmic expression of Btk... -
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