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Positive effects of porcine IL-2 and IL-4 on virus-specific immune responses induced by the porcine reproductive and respiratory syndrome virus (PRRSV) ORF5 DNA vaccine in swine

Tang D, Liu J, Li C, Zhang H, Ma P, Luo X, Zeng Z, Hong N, Liu X, Wang B, Wang F, Gan Z, Hao F

The purpose of this study was to investigate the effects of porcine interleukin (IL)-2 and IL-4 genes on enhancing the immunogenicity of a porcine reproductive and respiratory syndrome virus ORF5...
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A Novel Recombinant BCG Vaccine Encoding Eimeria tenella Rhomboid and Chicken IL-2 Induces Protective Immunity Against Coccidiosis

Wang Q, Chen L, Li J, Zheng J, Cai N, Gong P, Li S, Li H, Zhang X

  • KMID: 1792178
  • Korean J Parasitol.
  • 2014 Jun;52(3):251-256.
A novel recombinant Bacille Calmette-Guerin (rBCG) vaccine co-expressed Eimeria tenella rhomboid and cytokine chicken IL-2 (chIL-2) was constructed, and its efficacy against E. tenella challenge was observed. The rhomboid gene...
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Retroviral-mediated IL-2 gene transfer into murine neuroblastoma

Cho HS, Song JY, Park CY, Lyu CJ, Kim BS, Kim KY

We used retroviral-mediated gene transfer of the human interleukin (IL)-2 gene into murine neuroblastoma cells to investigate whether locally-secreted IL-2 is able to influence the generation of anti-tumor immune responses....
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