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Increased IL-12 and Interferon-Hamma, But Not IL-18 Production, After In Vitro Stimulation with a 30-kDa Mycobacterial Antigen in Patients with Tuberculous Pleurisy

Song CH, Jo EK, Kim HJ, Lim JH, Kim UO, Paik TH, Suhr JW, Park JK

  • KMID: 2099350
  • J Korean Soc Microbiol.
  • 2000 Oct;35(5):358-358.
No Abstract Available.
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The Role of Endogenous IL-18 in HIV-1 Production in Infected Peripheral Blood Mononuclear Cells

Choi HJ

No abstract available in English.
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Production of Interleukin(IL)-8, IL-18, and Soluble IL-18 Receptor by Whole Blood Cells from Women with Endometriosis

Lee HJ, Kim H, Park G, Ku SY, Kim SH, Choi YM, Kim JG

  • KMID: 2329564
  • J Reprod Endocrinol.
  • 2012 Oct;4(2):107-112.
OBJECTIVES: This study was investigated to evaluate the association between production of interleukin (IL)-8, IL-18, soluble IL-8 receptor (sIL-18R) from whole blood cells (WBCs) from women with and without endometriosis...
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Insulin Resistance and Serum Levels of Interleukin-17 and Interleukin-18 in Normal Pregnancy

Jahromi AS, Shojaei M, Ghobadifar MA

We performed this study to evaluate the role of Interleukin-17 (IL-17) and Interleukin-18 (IL-18) in insulin resistance during normal pregnancy. This descriptive cross sectional study was carried out on 97...
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Changes of Serum Interleukin-18 Levels in Kawasaki Disease

Jang GC, Lee SY, Kim DS

  • KMID: 2314235
  • Pediatr Allergy Respir Dis.
  • 2001 Jun;11(2):130-137.
PURPOSE: Interleukin 18(IL-18) is a potent proinflammatory cytokine which induces IFN-gamma, GM-CSF, TNF-alpha and IL-1, to activate killing by lymphocytes, and to up-regulate the expression of certain chemokine receptors. Kawasaki...
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Effects of Interleukin-18 on Allergic Response of Mouse Model

Yoon YH, Han WK, Park SW, Kim YM, Rha KS

  • KMID: 1875444
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2007 Nov;50(11):996-1000.
BACKGROUND AND OBJECTIVES: The imbalance between a Th1 response and a Th2 response may be one feature of allergic diseases' pathophysiology. IL-18, originally called the IFN-gamma inducing factor, stimulates both...
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Increased IL-12 , but Depressed IL-18 Production after In Vitro Stimulation with a 30-kDa Mycobacterial Antigen in Tuberculous Pleural Mononuclear Cells

Song CH, Jo EK, Kim SH, Kim HJ, Suhr JW, Paik TH, Nam HH, Lim JH, Kim UO, Lee JS, Park JK

  • KMID: 1571506
  • J Bacteriol Virol.
  • 2001 Sep;31(3):239-248.
In this study, we investigated interleukin (IL)-18 and IL-12 following in vitro stimulation with either the 30-kDa or purified protein derivative (PPD) antigens (Ag) of pleural mononuclear cells from 12...
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Circulating Interleukin-18 Level in Systemic Lupus Erythematosus

Lee YH, Song GG

OBJECTIVE: This study aimed to evaluate the relationship between circulating interleukin (IL)-18 levels and systemic lupus erythematosus (SLE) and establish a correlation between plasma/serum IL-18 levels and SLE activity. METHODS: We...
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Upregulation of IP-10(CXCL10) mRNA Expression by Interleukin-18

Kim HY, Kim HS

  • KMID: 2320155
  • Yeungnam Univ J Med.
  • 2007 Jun;24(1):67-78.
BACKGROUND: Interleukin-18 (IL-18) is one of the principal inducers of interferon-gamma (IFN-gamma) in lymphocytes. MATERIALS AND METHODS: The effect of IL-18 on the expression of chemokine IP-10(CXCL10) mRNA in C57BL/6 mouse...
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IL-18Ralpha Mediated GATA-3 Induction by Th2 Cells: IL-12 Supports IL-18Ralpha Expression in Th2 Cells

Joo IS, Sun MJ, Kim DY, Lee SJ, Ha YM, Cho JJ, Park CS, Ahn HJ

BACKGROUND: IL-18 was originally cloned as a IFN-gamma inducing factor in primed T cells. In synergy with IL-12, IL-18 has been shown to induce strikingly high levels of IFN-gamma production...
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Modulation of Humoral and Cell-Mediated Immunity Against Avian Influenza and Newcastle Disease Vaccines by Oral Administration of Salmonella enterica Serovar Typhimurium Expressing Chicken Interleukin-18

Rahman MM, Uyangaa E, Eo SK

Interleukin-18 (IL-18) has been known to induce interferon-gamma (IFN-gamma) production and promote Th1 immunity. Although mammalian IL-18 has been characterized in great detail, the properties and application of chicken IL-18...
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Determination and Significance of Serum Interleukin-18 Levels in Patients with Chronic Hepatitis B Virus Infection

Yoon DY, Lee KA, Park JK, Kim JW

  • KMID: 1730187
  • Korean J Lab Med.
  • 2004 Apr;24(2):139-145.
BACKGROUND: The aim of our study was to investigate the diagnostic value of interleukin-18 (IL-18) and other cytokines in chronic liver disease patients with hepatitis B virus (HBV), including chronic...
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The association study on infection of Mycobacterium leprae and RIPK2

Kim BC, Kang TJ, Chae GT

  • KMID: 1921046
  • Korean Lepr Bull.
  • 2003 Dec;36(2):23-29.
Receptor-interacting serine/threonine kinase 2(RIPK2) is an adaptor molecule involved in the signal pathway of TLRs. However, there is no report on association between RIPK2 expression and infectious disease including...
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Comparison of Serum Interleukin-18 Levels, Biochemical Profiles and the Duration of Fever in the Acute and Subacute Phase of Kawasaki Disease

Bae JH, Kim JH, Byun SO

  • KMID: 1852891
  • J Korean Pediatr Cardiol Soc.
  • 2006 Sep;10(3):309-316.
PURPOSE: Interleukin 18 (IL-18) is now recognized as an important regulator of innate and acquired immune response. IL-18 is a proinflammatory cytokine which induces IFN-gamma, TNF-alpha, Granulocyte-macrophage Colony-stimulating factor (GM-CSF),...
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Successful Treatment with Etanercept in a Patient with Adult-onset Still's Disease

Woo H, Kim OK, Lee GH, Park JJ, Lee SS, Park YW

  • KMID: 2202205
  • J Korean Rheum Assoc.
  • 2006 Dec;13(4):306-310.
Adult-onset Still's disease (AOSD) is a rare systemic inflammatory disorder of unknown etiology. Non-steroidal anti-inflammatory drugs (NSAIDs), steroids, disease modifying anti-rheumatic drugs (DMARDs), immunosuppressives and intravenous immunoglobulin (IVIG) have been...
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Study of serum interleukin (IL) 18 and IL-6 levels in relation with the clinical disease severity in chronic idiopathic urticaria patients of Kashmir (North India)

Rasool R, Ashiq I, Shera IA, Yousuf Q, Shah ZA

BACKGROUND: Chronic urticaria is termed as idiopathic if there is an absence of any identifiable causes of mast cell and basophil degranulation. Various cytokines have been found to be involved...
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PKR as a Regulator of Inflammasome Activation

Manzoor Z, Koh YS

Detection of pathogen by pattern recognition receptors leads to activation of inflammasome which plays a crucial role in immune system. The inflammasome regulates the release of cytokines, such as interleukin...
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Biomarkers in Acute Kidney Injury

Cho MH

  • KMID: 2196705
  • J Korean Soc Pediatr Nephrol.
  • 2011 Oct;15(2):116-124.
Acute kidney injury (AKI) can result in mortality or progress to chronic kidney disease in hospitalized patients. Although serum creatinine has long been used as the best biomarker for diagnosis...
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Clinical Significance of Serum Interleukin-18 Concentration in the Patients with Atopic Dermatitis

Park DS, Youn YH

BACKGROUND: Interleukin (IL)-18, a potent inducer of interferon gamma (IFN-gamma), is known to have a role in diseases involving type-2 T helper cell responses including atopic dermatitis. In this...
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Correlation between Cytokine and Chemokine levels and Clinical Severity in Children with Mycoplasma pneumoniae Pneumonia

Choi HJ, Kim YH

PURPOSE: The aim of this study was to evaluate the relationships between cytokine and chemokine levels and the clinical severity of Mycoplasma pneumoniae pneumonia. METHODS: A retrospective analysis of clinical and...
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