- IL-1B-31 and IL-1Ra polymorphisms associated with increased host susceptibility to immune thrompocytopenia
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Kim J
- KMID: 2405055
- Blood Res.
- 2017 Dec;52(4):235-236.
- doi: 10.5045/br.2017.52.4.235
No abstract available. -
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- Evaluation of the Interleukin-1 Receptor Antagonist and Immunoregulatory Interleukin-10 in the Middle Ear in Chronic Otitis Media With Effusion in Children With and Without Atopy
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Zielnik-Jurkiewicz B, Stankiewicz-Szymczak W
- KMID: 2165051
- Clin Exp Otorhinolaryngol.
- 2016 Jun;9(2):104-108.
- doi: 10.21053/ceo.2015.00129
OBJECTIVES: The role of pro-inflammatory cytokines in the course of chronic otitis media with effusion (COME) has been documented. However, there are fewer studies on the action of anti-inflammatory cytokines... -
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- Changes of plasma interleukin-1 receptor antagonist, interleukin-8 and other serologic markers during chemotherapy in patients with active pulmonary tuberculosis
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Lee JH, Chang JH
- KMID: 1866912
- Korean J Med.
- 2002 May;62(5):513-521.
BACKGROUND: The human immune response to Mycobacterium tuberculosis is mediated by macrophage and T-lymphocyte. The alveolar macrophage phagocyting mycobacterium produced interleukin (IL)-1 as an inflammatory mediator and IL-8 as a... -
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- Improvement of Erdheim-Chester disease-related renal failure after treatment with anakinra
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Podesta MA, Graziani G, Reggiani F, Buemi M, Badalamenti S, Ponticelli C
- KMID: 2028694
- Kidney Res Clin Pract.
- 2014 Sep;33(3):165-167.
- doi: 10.1016/j.krcp.2014.07.007
Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis characterized by infiltrates of lipid-laden CD68+/CD1- histiocytes, affecting heart, lungs, central nervous system, and bones. Kidney and adjacent structures can also... -
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- Biologic Therapy in Rheumatoid Arthritis
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Koh EM
- KMID: 2168065
- Hanyang Med Rev.
- 2005 May;25(2):80-88.
Rheumatoid arthritis (RA) is a common autoimmune disease of unknown etiology characterized by symmetric and erosive synovitis. The course of RA is usually chronic and progressive, so it can result... -
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- A Case of Schnitzler's Syndrome without Monoclonal Gammopathy-Associated Chronic Urticaria Treated with Anakinra
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Ahn MJ, Yu JE, Jeong J, Sim DW, Koh YI
- KMID: 2418863
- Yonsei Med J.
- 2018 Jan;59(1):154-157.
- doi: 10.3349/ymj.2018.59.1.154
Chronic urticaria may often be associated with interleukin (IL)-1-mediated autoinflammatory disease, which should be suspected if systemic inflammation signs are present. Here, we report a case of Schnitzler's syndrome without... -
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- A Case of Adult Onset Still's Disease with Severe Pneumonitis Treated with Anakinra
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Cho SH, Kim OZ, Cho SW, Lim DM, An SK, Kim CK
- KMID: 1710040
- Korean J Med.
- 2014 Aug;87(2):245-250.
- doi: 10.3904/kjm.2014.87.2.245
Adult onset Still's disease (AOSD) is a systemic autoinflammatory disorder that presents with recurrent fever, extreme fatigue, and joint pain. Pulmonary involvement is not uncommon and, although rare, severe pneumonitis... -
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- The relationship between interleukin-1 receptor antagonist gene polymorphism and bone mineral density in postmenopausal Korean women
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Kim JG, Kim SH, Choi YM, Moon SY, Lee JY
- KMID: 2270270
- Korean J Obstet Gynecol.
- 2002 Jun;45(6):926-931.
OBJECTIVE: To investigate the relationship between polymorphism in interleukin-1 receptor antagonist (IL-1ra) gene and bone mineral density (BMD) in postmenopausal Korean women. METHODS: The 86-base pair repeat polymorphism in the... -
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- The role of cytokines in seizures: interleukin (IL)-1beta, IL-1Ra, IL-8, and IL-10
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Youn Y, Sung IK, Lee IG
- KMID: 2284252
- Korean J Pediatr.
- 2013 Jul;56(7):271-274.
- doi: 10.3345/kjp.2013.56.7.271
Brain insults, including neurotrauma, infection, and perinatal injuries such as hypoxic ischemic encephalopathy, generate inflammation in the brain. These inflammatory cascades induce a wide spectrum of cytokines, which can cause... -
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- Intranasal Administration of Interleukin-1 Receptor Antagonist in a Transient Focal Cerebral Ischemia Rat Model
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Lee JH, Kam EH, Kim JM, Kim SY, Kim EJ, Cheon SY, Koo BN
- KMID: 2375034
- Biomol Ther.
- 2017 Mar;25(2):149-157.
- doi: 10.4062/biomolther.2016.050
The interleukin-1 receptor antagonist (IL-1RA) is a potential stroke treatment candidate. Intranasal delivery is a novel method thereby a therapeutic protein can be penetrated into the brain parenchyma by bypassing... -
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- Analysis of Cytokines in Sera from Type 1 Diabetic Patients at Diagnosis
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Yoon IS, Shin CH, Yang SW
- KMID: 1450618
- J Korean Soc Pediatr Endocrinol.
- 2011 Apr;16(1):13-19.
- doi: 10.6065/jkspe.2011.16.1.13
PURPOSE: Diverse cytokines influence the pathogenesis of type 1 diabetes mellitus (T1DM) in different ways. We studied the profile of cytokines in sera from type 1 diabetic patients at diagnosis. METHODS:... -
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- The Induction of Apoptosis by Fas Antibody, IFN - delta, IL - 1 alpha in Normal Human Keratinocytes and KB cells
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Lee HK, Whang KU, Park YL, Kim YK, Norris DA
- KMID: 2230637
- Korean J Dermatol.
- 1997 Apr;35(2):273-278.
BACKGROUND: The Fas antigen is a cell surface molecule that mediates apoptosis in many cell types. Matsues group indicated that keratinocytes constitutively express the Fas antigen and apoptosis was induced... -
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- Polymorphisms of interleukin-1beta and interleukin-1 receptor antagonist genes in patients with pulmonary tuberculosis
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Jeon DS, Lee JH, Lee SJ, Jo WH, Jeong KS, Kim KW, Kim YS, Lee MK, Kim YD, Choi YM, Park SK, Park SK
- KMID: 1984604
- Korean J Med.
- 2005 Mar;68(3):284-291.
BACKGROUND: Several lines of evidence suggest that host genetic factors influence the outcome of exposure to Mycobacterium tuberculosis. The aim of this study was to determine whether polymorphisms in interleukin-1beta... -
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- The Effect of Interleukin-1 on The Production of Insulin-Like Growth Factors and Their Binding Proteins in Human Granulosa-Luteal Cells
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Lee JY, Min EG, Kim JK, Suh CS, Kim SH, Choi YM, Moon SY
- KMID: 2261050
- Korean J Obstet Gynecol.
- 1998 Jul;41(7):1795-1804.
The relationship between the immune system and the endocrine system in the ovary has become of an challenging and exciting subject to reproductive scientists. The intraovarian regulators such as insulin-like... -
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- IL-1 Receptor Antagonist Reduced Chemical-Induced Keratinocyte Apoptosis through Antagonism to IL-1α/IL-1β
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Lee H, Cheong KA, Kim JY, Kim NH, Noh M, Lee AY
- KMID: 2420393
- Biomol Ther.
- 2018 Jul;26(4):417-423.
- doi: 10.4062/biomolther.2017.167
Extracellular interleukin 1 alpha (IL-1α) released from keratinocytes is one of the endpoints for in vitro assessments of skin irritancy. Although cells dying via primary skin irritation undergo apoptosis as... -
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- Interleukin 1 Receptor Antagonist(IL-1ra) Gene Polymorphism in Children with Henoch-Schonlein Purpura Nephritis
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Hwang PK, Lee JN, Chung WY
- KMID: 1627742
- J Korean Soc Pediatr Nephrol.
- 2005 Oct;9(2):175-182.
PURPOSE: Interleukin 1 receptor antagonist(IL-1ra) is an endogenous antiinflammatory agent that binds to IL-1 receptor and thus competitively inhibits the binding of IL-1alpha and IL-1beta. Allele 2 in association with... -
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- Role of Salvia miltiorrhiza for Modulation of Th2-derived Cytokines in the Resolution of Inflammation
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Moon S, Shin S, Kim S, Oh HE, Han S, Lee S, Kim K
- KMID: 2168001
- Immune Netw.
- 2011 Oct;11(5):288-298.
- doi: 10.4110/in.2011.11.5.288
BACKGROUND: Salvia miltiorrhiza (SM) has been used to treat inflammatory diseases including edema and arthritis; however, the anti-inflammatory mechanism of SM action remains unresolved. METHODS: The effects of an ethanol extract of... -
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- IL-1beta and IL-1 Receptor Antagonist Gene Polymorphisms in Myasthenia Gravis
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Park JH, Kim HS, Kim WJ, Kim DS, Choi YC
- KMID: 2185335
- J Korean Neurol Assoc.
- 2005 Aug;23(4):484-489.
BACKGROUND: Myasthenia gravis (MG) is an autoimmune disorder characterized by an immune response against the nicotinic acetylcholine receptor at the neuromuscular junction. Genetic factors as well as abnormalities of immune... -
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- Quantitative Analysis of Tissue Injury after Minimally Invasive Total Hip Arthroplasty
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Kwak S, Chun Y, Rhyu K, Cha J, Cho Y
- KMID: 1794708
- Clin Orthop Surg.
- 2014 Sep;6(3):279-284.
- doi: 10.4055/cios.2014.6.3.279
BACKGROUND: We intended to clarify the hypothesis that minimally invasive total hip arthroplasty (MI-THA) leads to less tissue damage and inflammatory response than does conventional total hip arthroplasty (C-THA). METHODS: We... -
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- The Allele 2 of the VNTR Polymorphism in the Gene That Encodes a Natural Inhibitor of IL-1β, IL-1RA Is Favorably Associated With Chronic Otitis Media
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Živković M, Kolić I, Jesić S, Jotić A, Stanković A
- KMID: 2412669
- Clin Exp Otorhinolaryngol.
- 2018 Jun;11(2):118-123.
- doi: 10.21053/ceo.2017.01060
OBJECTIVES: Chronic otitis media (COM) is followed by irreversible tissue damage and destruction of the middle ear structures, with the possibility of complications under the maintenance of inflammation. Inflammatory mediators... -
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