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Insulin-like growth factor-I and II and insulin-like growth factor binding protein-3 in amniotic fluid at second trimester: A correlation with birth weight

Kim JY, Yang SH, Lee IS

  • KMID: 2076221
  • Korean J Obstet Gynecol.
  • 2001 Apr;44(4):668-673.
OBJECTIVE: o determine the correlation between birth weight and the level of insulin-like growth factor(IGF)-I, -II and insulin-like growth factor binding protein(IGFBP)-3 in amniotic fluid at second trimester and to...
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Increasing Plasma Insulin-Like Growth Factor II Levels are Associated with Metastasis of Hepatocellular Carcinoma Following Transcatheter Arterial Chemoembolization

Song BC, Chung YH, Kim JA, Yang SH, Lee HC, Yoon HK, Sung KB, Jung SA, Yoo K, Lee YS, Suh DJ

  • KMID: 2240268
  • Korean J Gastroenterol.
  • 2000 Sep;36(3):361-371.
No Abstract Available.
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Profile of Insulin, Growth Hormone and Insulin-like Growth Factors in Human Cord Blood According to Birth Weight

Kim HY, Lee DY, Cho SC

  • KMID: 2335376
  • J Korean Pediatr Soc.
  • 1998 Nov;41(11):1484-1490.
PURPOSE: Insulin-like growth factors (IGFs) are mitogenic peptides that are essential for fetal and maternal tissue growth during pregnancy. They circulate primarily with serum IGF-binding protein (IGFBP) which regulates the...
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A Case of non-islet Cell Tumor Hypoglycemia Due to Gepatoma-increased serum subfraction of big insulin-like growth factor II

Lee KW, Kim HS, Chung YS, Kim HM, Yoon MH, Ko JH, Kim HC, Kim YS, Cho SW

  • KMID: 2331099
  • J Korean Soc Endocrinol.
  • 1997 Dec;12(4):667-671.
Hypoglycemia due to non-islet cell tumor is usually associated with hypersecretion of big insulin-like growth factor II (IGF-II). This big IGF-II cannot form ternary IGF complex, and is biologically more...
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Profiles of Insulin-like Growth Factor[IGF]s , their Binding Protein[IGFBP]s and IGFBP-3 Protease Activity in Peritoneal Fluid of Patients with Endometriosis

Kim JK, Suh CS, Kim SH, Choi YM, Moon SY, Kang SB, Lee JY

  • KMID: 2269603
  • Korean J Obstet Gynecol.
  • 1999 May;42(5):1011-1017.
OBJECTIVES: To test if IGF[insulin-like growth factor] components in peritoneal fluid[PF] of patients with endometriosis may be involved in the growth of ectopic endometrium. METHODS: In peritoneal fluid[PF] obtained from...
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Growth Status and Levels of Growth Factors in Children with Insulin-dependent Diabetes Mellitus

Chung SC, Kim DH

  • KMID: 2335360
  • J Korean Pediatr Soc.
  • 1998 Aug;41(8):1102-1110.
PURPOSE: It is well known that the linear growth velocity in children with insulin-dependent diabetes mellitus (type 1 DM) is closely related to metabolic control and onset age of the...
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Alteration of Serum Insulin-like Growth Factor(IGF)-I and IGF-Binding Protein-2 in Healthy Population with Aging

Yoon KC, Lee DY

  • KMID: 2193909
  • J Korean Soc Pediatr Endocrinol.
  • 1998 May;3(1):7-12.
PURPOSE:Insulin-like growth factors, IGF- I and IGF-II, are proteins that promote cellular growth and differentiation of the various organs including the kidney. These peptides circulate in serum bound to...
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Insulin-Like Growth Factors and Their Bindign Proteins in Uterine Leiomyoma Pretreated with Gonadtropin Releasing Hormone Agonist

Kim KC, Kim JG, Lee JY

  • KMID: 1999282
  • J Korean Soc Endocrinol.
  • 1997 Sep;12(3):364-375.
BACKGROUND: Uterine leiomyoma is the most common pelvic tumor, occurring in 20-25% of women in reproductive age. Gonadotropin releasing hormone agonist (GnRHa) has been reognized as a temporary medical management...
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A Case of Non-islet Cell Tumor Hypoglycemia

Chae YT, Hwang IJ, Ryu KH, Ko EH, Rue JI, Kim SK, Park SW, Kim YR, Cho YW, Choi YK, Lee SJ

Mesenchymal tumors including hemangiopericytomas, hepatocellular tumors, adrenal carcinomas, and a variety of other large tumors have been reported to produce excessive amounts of insulin-like growth factor (IGF) type II precursor,...
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The Correlation of Ovarian Follicular Concentrations of IGF-II, IGFBP-1, and 3 between Cumulative Embryo Score in Patients Undergoing IVF-ET

Kwon HE, Hong SH, Park CY, Kim SH, Chae HD, Kim CH, Kang BM, Nam JH

  • KMID: 2272039
  • Korean J Obstet Gynecol.
  • 2003 May;46(5):970-977.
OBJECTIVE: To investigate the correlation between the concentrations of insulin-like growth factor-II (IGF-II), insulin-like growth factor binding protein-1, 3 (IGFBP-1, 3) in the follicular fluid and the cumulative embryo score...
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Serum Insulin-like Growth Factors and their Binding Proteins in the Women With Polycystic Ovary

Roh JS, Yoo JB, Jo SH, Kim HS, Hwang YY

  • KMID: 2261935
  • Korean J Obstet Gynecol.
  • 2000 May;43(5):795-805.
OBJECTIVE: The involvement of IGF system in hyperandrogenism and abnormal follicular development is controversial. This study is to assess whether IGF system contribute to it in the women with polycystic ovary(PCO). METHODS:...
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Neurotoxic Effect of Streptozotocin and Neuroprotective Effect of Insulin Growth Factor-II to the Cultured Mouse Schwann Cells

Jang CH, Park ST

  • KMID: 2012698
  • Korean J Otolaryngol-Head Neck Surg.
  • 2000 Jun;43(6):577-581.
BACKGROUND: The sensorineural hearing loss due to diabetes is progressive and bilateral, and predominantly occurs in the old, although its accurate pathogenesis is still unknown. Objectives: The purpose of this...
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The Tumor Suppressor Function of PTEN/MMAC1 through the Regulation of IGFs and IGFBPs

Yi HK, Hwang DJ, Kim SY, Lee DY, Hwang PH

  • KMID: 1875814
  • Korean J Pediatr.
  • 2004 Aug;47(8):884-891.
PURPOSE: PTEN/MMAC1, a novel tumor suppressor gene, is mutated in a variety of advanced and metastatic cancers. It acts as a phosphatase, and thereby, regulates the PI-3 kinase/Akt pathway. In...
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Clinical Efficacy of Serum Insulin-like Growth Factor- I (IGF-I), IGF-II, and IGF Binding Protein-3 (IGFBP-3) in Predicting the Prognosis of In Vitro Fertilization and Embryo Transfer

Kim SH, Ku SY, Jee BC, Suh CS, Choi YM, Kim JG, Moon SY

  • KMID: 2272013
  • Korean J Obstet Gynecol.
  • 2003 Apr;46(4):802-809.
OBJECTIVE: To evaluate the clinical efficacy of serum insulin-like growth factor-I (IGF-I), IGF-II, and IGF binding protein-3 (IGFBP-3) levels in predicting the prognosis of in vitro fertilization and embryo transfer...
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Effects of Glycemic Control on Growth and IGF-I, IGF-II, IGFBPs in Insulin dependent Diabetic Children

Kim DH, Rho KS, Chung SC

  • KMID: 2331682
  • J Korean Diabetes Assoc.
  • 1998 Sep;22(3):392-402.
BACKGROUND: It is well known that linear growth velocity in diabetic children is closely related to metabolic control and age of onset. Many studies demonstrated growth impairment in diabetic children...
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Characteristics of Serum Insulin-like Growth Factor ( IGF ) and IGF-Bindign Protein-3 during Pregnancy

Lee DY, Kim JS, Lee HR, Rhee CH, Cho SC

  • KMID: 1999283
  • J Korean Soc Endocrinol.
  • 1997 Sep;12(3):376-385.
BACKGROUND: Pregnancy in human and rodents is associated with dramatic matemal metabolic changes. Insulin-like growth factors (IGFs) are mitogenic peptides that are essential for fetal and maternal tissue growth during...
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The Case of Accelerated Linear Growth Despite Growth Hormone and Insulin-like Growth Factor-I Deficiency

Lee KJ, Hahm JR, Jung TS, Jung JH, Kim SK, Baek JH, Lee WH, Yoo HW, Chung SI

Here we describe a male patient who attained normal height despite combined hypopituitarism with an abnormal growth hormone-insulin-like growth factor (IGF)-I axis. When he was an 18-year-old, he presented with...
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Transforming Growth Factor-alpha Regulation of Insulin-like Growth Factor-II, Insulin-like Growth Factor Binding Protein-1 and 3 secretion and Epidermal Growth Factor receptor expression in human luteinized granulosa cells

Kang EH, Hong SH, Cho JS, Kim SH, Chae HD, Kim CH, Kang BM, Nam JH

  • KMID: 2270618
  • Korean J Obstet Gynecol.
  • 2002 Dec;45(12):2130-2139.
OBJECTIVE: To investigate the effects of transforming growth factor (TGF)-alpha on insulin-like growth factor (IGF)-II, insulin-like growth factor binding protein (IGFBP)-1, and 3 secretion and epidermal growth factor (EGF) receptor...
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Influence of Tumor Necrosis Factor-alpha on Expression of Insulin-like Growth Factor-II, Insulin-like Growth Factor Binding Protein-1, 2, 3, 5 in Cultured Human Luteinized Granulosa Cells

Hong SH, Hong SH, Kim SH, Chae HD, Kim CH, Kang BM

  • KMID: 2013163
  • Korean J Obstet Gynecol.
  • 2006 Mar;49(3):633-643.
OBJECTIVE: To investigate the influence of tumor necrosis factor (TNF)-alpha on the expression of insulin-like growth factor (IGF)-II, insulin-like growth factor binding protein (IGFBP)-1, 2, 3, and 5 mRNA in...
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Modulation of irradiation-induced cell death by insulin-like growth factor-ii in MC3T3 osteoblasts

Park KL

  • KMID: 1814526
  • J Korean Assoc Oral Maxillofac Surg.
  • 2007 Dec;33(6):617-624.
Insulin-like growth factor (IGF) is the most abundant growth factor in bone matrix. Recent studies have shown that it can sensitize apoptotic cell death of osteoblasts. Thus, this study investigated...
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