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The “Ghost of Epidemics” Personified in Two Joseon Dynasty Tales

Hwang K

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Clinical Utility of Procalcitonin on Antibiotic Stewardship: A Narrative Review

Kim JH

Procalcitonin (PCT) was discovered as a useful marker for bacterial infection. Following its discovery, there have been a substantial number of clinical studies conducted to evaluate the presence of bacterial...
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SARS-CoV-2 Breakthrough Infection after mRNA-1273 Booster among CoronaVac-Vaccinated Healthcare Workers

Santi T, Kamarga L, Samakto BD, Jo J

It remains unknown whether the Indonesian healthcare workers (HCWs) who had received two doses of CoronaVac vaccine and one dose of mRNA-1273 booster could be protected during the severe acute...
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Vaccination Rates of Hospitalized Patients at High Risk of Severe COVID-19: A Single-Center CrossSectional Study

Nham E, Hyun H, Seong H, Yoon JG, Noh JY, Song JY, Kim WJ, Cheong HJ

We investigated coronavirus disease 2019 (COVID-19) vaccination rate in patients admitted to chronic pulmonary disease, cardiovascular disease, chronic kidney disease, and cancer wards in the third week of April 2022...
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Co-Infection in COVID-19 Pneumonia: Discussion Continues

Strelkova D, Rachina S, Klimenko A, Yatsyshina S, Cheboksarov D, Cherkasova T, Ramazanov N, Ananicheva N

Sixty-six patients with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 and pneumonia on chest computer tomography were prospectively recruited. A combined respiratory swab for polymerase chain reaction (PCR), urine sample...
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Successful Treatment of VancomycinResistant Enterococcus species Bone and Joint Infection with Daptomycin Plus Beta Lactam Agents

La YJ, Kim YC

Bone and joint infections (BJI) caused by vancomycin-resistant Enterococcus spp. (VRE) are difficult to treat due to limited antibiotic options. Although linezolid can be used for VRE treatment, it is...
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Impact of Inappropriate Empirical Antibiotic on Outcomes in Community-acquired Third Generation Cephalosporin Resistant Enterobacterales Bacteremia

Nasomsong W, Changpradub D, Vasikasin V

Background: Currently, third generation cephalosporin resistant Enterobacterales (3GCRE) are becoming more common in community-acquired infection, leading to increasing consumption of carbapenems. Because community-acquired 3GCRE infections are generally less severe and...
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Nirmatrelvir/Ritonavir Prescription Rate and Outcomes in Coronavirus Disease 2019: A Single Center Study

Park JJ, Lee J, Seo YB, Na SH

Background: Nirmatrelvir/ritonavir was Korea's first oral antiviral agent to treat coronavirus disease 2019 (COVID-19). We analyzed the nirmatrelvir/ritonavir prescription rate and treatment outcomes in treatment-eligible patients with COVID-19 receiving home-based...
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Liver Abscess caused by Cytomegalovirus in a Patient with Acquired Immunodeficiency Syndrome

Lee JY, Park Jw, Park JY

Cytomegalovirus (CMV) causes severe infection in immunocompromised patients, especially those with acquired immunodeficiency syndrome (AIDS), those who have undergone organ transplantation, and/or those who are being treated with steroids. In...
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Current Status of Antibiotic Stewardship and the Role of Biomarkers in Antibiotic Stewardship Programs

Kim CJ

The importance of antibiotic stewardship is increasingly emphasized in accordance with the increasing incidences of multidrug-resistant organisms and accompanying increases in disease burden. This review describes the obstacles in operating...
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Prescription Pattern of Intravenous Fosfomycin in a Provincial Hospital in Thailand

Thampithak A, Chaisiri K, Siangsuebchart O, Phengjaturat K, Aonjumras W, Hemapanpairoa J

Background: In Thailand, active antibiotics against Gram-negative bacteria are limited. The re-emergence of intravenous (IV) fosfomycin is an alternative. IV fosfomycin has broadspectrum activity, relative safety, and availability. The limitations...
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Use of the Monoclonal Antibody Regdanvimab to Treat Patients Hospitalized with COVID-19: Real-World Data during the Delta Variant Predominance

Kwak YG, Song JE, Kang J, Kang J, Kang HK, Koo HK, Park HK, Choi SB, Lee HP, Lee MJ, Kim BN

Regdanvimab is the only monoclonal antibody available in Korea that targets severe acute respiratory syndrome coronavirus 2. We retrospectively evaluated the clinical characteristics of 374 adults hospitalized with coronavirus disease...
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A Korean Post-Marketing Surveillance Study of Dolutegravir Single-Agent Tablets in Patients with HIV-1

Kwon S, Cho JE, Lee EB, Kim YS, Sohn JW

Background: The integrase strand transfer inhibitor dolutegravir has been indicated in Korea since 2014 for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in combination with other antiretroviral...
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Changing Features of Liver Injury in COVID-19 Patients: Impact of Infection with the SARS-CoV-2 Delta (B.1.617.2) Variants

Choi CW, Sung HK, Jeong JY, Lim DH, Choi J, Kwon HC, Nam S, Kim Y, Chin B

Background: There is growing evidence that abnormal liver function tests (LFTs) are common in patients with coronavirus disease 2019 (COVID-19). However, it is not known whether viral involvement in the...
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Current Status and Prospect of Qualitative Assessment of Antibiotics Prescriptions

Park SY, Kim YC, Lee R, Kim B, Moon SM, Kim HB, Korea Study Group for Antimicrobial Stewardship

Identifying inappropriately prescribed antibiotics for infectious diseases by monitoring the quality of antibiotics use is essential for effective implementation of antibiotic stewardship. Qualitative assessment of the use of antibiotics has...
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Korean Guidelines for Use of Antibiotics for Intra-abdominal Infections in Adults

Yoon YK, Moon C, Kim J, Heo ST, Lee MS, Lee S, Kwon KT, Kim SW, Korean Society for Antimicrobial Therapy and Korean Society of Infectious Diseases

The guidelines are intended to provide practical information for the correct use of antibiotics for intra-abdominal infections in Korea. With the aim of realizing evidence-based treatment, these guidelines for the...
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Implementation of Procalcitonin in Antibiotic Stewardship: Derivation of a Consensus Algorithm for Procalcitonin Use in Clinical Practice

Park DW, Choi JY, Kim CJ, Kim JH, Kim HB, Lee DG

Reducing antibiotics overuse is essential to minimize antibiotics related side effects and to prevent the emergence of multidrug-resistant bacteria. Procalcitonin (PCT) guided antibiotics therapy has been reported to be safe...
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Implementation of a Nurse-Delivered Cognitive Behavioral Therapy for Adherence and Depression of People Living with HIV in Korea

Kim JH, Kim JM, Ye M, Lee JI, Na S, Lee Y, Short D, Choi JY

Background: Cognitive behavioral therapy for adherence and depression (CBT-AD) performed by clinical psychologists is an effective treatment for improving the depression in people living with HIV (PLWH). However, because access...
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First Isolates of OXA-48-Like Carbapenemase-Producing Enterobacteriaceae in A Specialized Cancer Center

Villanueva-Cotrina F, Condori DM, Gomez TO, Yactayo KM, Barron-Pastor H

Background: OXA-48-like carbapenemases have been found in a growing and varied number of carbapenemase-producing Enterobacteriaceae (CPE) isolates, and they are spreading to several countries. Although this oxacillinase leads to weak...
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Core Elements for Implementing Antimicrobial Stewardship Programs in Korean General Hospitals

Cheong HS, Park KH, Kim HB, Kim SW, Kim B, Moon C, Lee MS, Yoon YK, Jeong SJ, Kim YC, Eun BW, Lee H, Shin JY, Kim Hs, Hwang IS, Park CS, Kwon KT, Korean Society for Antimicrobial Therapy, The Korean Society of Infectious Diseases, Korean Society

Currently, antimicrobial resistance (AMR) is a major threat to global public health. The antimicrobial stewardship program (ASP) has been proposed as an important approach to overcome this crisis. ASP supports...
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