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Disease-specific pluripotent stem cells

Kang HC

Induced pluripotent stem (iPS) cells are generated by epigenetic reprogramming of somatic cells through the exogenous expression of transcription factors. Recently, the generation of iPS cells from patients with a...
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Clinical Applications of Neural Stem Cells for the Treatment of Peripheral Neuropathy

Park JM, Choi BO

Extraordinary advances in stem cell research have initiated an era of hope for strategies to treat intractable human diseases. Personalized regenerative treatment using stem cells is expected to accelerate continuous...
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Stem Cell Properties of Therapeutic Potential

Seo GS

Stem cell research is a innovative technology that focuses on using undifferentiated cells able to self-renew through the asymmetrical or symmetrical divisions. Three types of stem cells have been studied...
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Questions Surrounding iPS Cells in Japan

Yui Y

No abstract available.
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Stem cells: general information and perspectives

Huh YJ, Kim DW

We are now in the middle of stem cell war. Each country is trying to invest a large amount of funds into stem cell research. This is due to a...
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Induced pluripotent stem cells and personalized medicine: current progress and future perspectives

Chun YS, Byun K, Lee B

Generation of induced pluripotent stem cells (iPSCs) has revolutionized the field of regenerative medicine by providing researchers with a unique tool to derive disease-specific stem cells for study. iPSCs can...
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Engineering Biomaterials for Feeder-Free Maintenance of Human Pluripotent Stem Cells

Yang K, Lee J, Cho SW

  • KMID: 1426150
  • Int J Stem Cells.
  • 2012 May;5(1):1-5.
Human pluripotent stem cells (hPSCs) are capable of differentiating into any type of somatic cell, a characteristic that imparts significant therapeutic potential. Human embryonic stem cells and induced pluripotent stem...
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Disease Specific Induced Pluripotent Stem Cells by Using Transcription Factors

Kang HC

  • KMID: 2329439
  • J Korean Child Neurol Soc.
  • 2010 May;18(1):1-6.
The recent years have seen great advances in reversal of programming of differentiated somatic cells towards pluripotency by methods not involving nuclear transfer. Although differentiation of cells involves complex genetic...
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Induced Pluripotent Stem Cells: Next Generation Stem Cells to Clinical Applications

Cha J, Park S, Lee SB

Induced pluripotent stem cells (iPSC) are specially manipulated cells from somatic cells by the introduction of four factors that are reprogrammed. The properties of iPSC are similar to embryonic stem...
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Application of Induced Pluripotent Stem Cells in Rheumatology

Jung SM, Ju JH

Since induced pluripotent stem cell (iPSC) was first introduced by Yamanaka in 2006, it took only six years to win a Nobel Prize for his pioneering work. It is unusual...
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New Advances in Human X Chromosome Status from a Developmental and Stem Cell Biology

Patterson , Tanaka Y, Park IH

Recent advances in stem cell biology have dramatically increased the understanding of molecular and cellular mechanism of pluripotency and cell fate determination. Additionally, pluripotent stem cells (PSCs), including embryonic stem...
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Stem Cells in Drug Screening for Neurodegenerative Disease

Kim HJ, Jin CY

Because the average human life span has recently increased, the number of patients who are diagnosed with neurodegenerative diseases has escalated. Recent advances in stem cell research have given us...
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Induced Pluripotent Stem Cells as a Novel Tool in Psychiatric Research

Kim S, Kim MK, Oh D, Lee SH, Kim B

Reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) provides a valuable opportunity to study neurodevelopmental and neurodegenerative psychiatric diseases by offering an unlimited source for patient-specific neuronal and...
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Adipose Tissue - Adequate, Accessible Regenerative Material

Kolaparthy LK, Sanivarapu S, Moogla S, Kutcham RS

The potential use of stem cell based therapies for the repair and regeneration of various tissues offers a paradigm shift that may provide alternative therapeutic solutions for a number of...
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Is Stem Cell-Based Therapy Going on or Out for Cardiac Disease?

Byun KH, Kim SW

Acute myocardial infarction and subsequent heart failure are leading causes of death worldwide. Stem cell-based therapies have improved cardiac function in recent clinical trials, but cardiomyocyte regeneration has not been...
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Stem Cell Therapy for Type 1 Diabetes Mellitus

Yoo EG

Type 1 diabetes mellitus (T1DM) is caused by autoimmune destruction of insulin producing beta cells, and theoretically, it can be cured by replacement of the lost beta cells. The limitations...
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Current Stem Cell Therapy for Osteoarthritis

Nam Y, Rim YA, Ju JH

Osteoarthritis is a musculoskeletal disease representative of an aging society. As medical conditions are usually complicated in an aging population, osteoarthritis becomes more frequently encountered in the physician's office. There...
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Neuronal Differentiation of a Human Induced Pluripotent Stem Cell Line (FS-1) Derived from Newborn Foreskin Fibroblasts

Kwon J, Lee N, Jeon I, Lee HJ, Do JT, Lee DR, Oh SH, Shin DA, Kim A, Song J

  • KMID: 1735408
  • Int J Stem Cells.
  • 2012 Nov;5(2):140-145.
Isolation of induced pluripotent stem cells (iPSCs) from fully differentiated somatic cells has revolutionized existing concepts of cell differentiation and stem cells. Importantly, iPSCs generated from somatic cells of patients...
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Regulation of Neural Stem Cell Fate by Natural Products

Kim HJ

Neural stem cells (NSCs) can proliferate and differentiate into multiple cell types that constitute the nervous system. NSCs can be derived from developing fetuses, embryonic stem cells, or induced pluripotent...
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Modeling of Human Genetic Diseases Via Cellular Reprogramming

Kang MY, Suh JH, Han YM

The generation of induced pluripotent stem cells (iPSCs) derived from patients' somatic cells provides a new paradigm for studying human genetic diseases. Human iPSCs which have similar properties of human...
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