- Dexamethasone differentiates NG108-15 cells through cyclooxygenase1 induction
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Kim HS, Song M, Kim E, Ryu SH, Suh PG
- KMID: 1094702
- Exp Mol Med.
- 2003 Jun;35(3):203-210.
Cyclooxygenase (COX) is a key enzyme in the conversion of arachidonic acid into prostanoids which participate in various cellular functions including apoptosis, mitogenesis, inflammation, immune modulation and differentiation. Moreover, the... -
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- Effects of mastoparan on a vascular contractility in rabbit aorta
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Lee YH, Kang SI, Ahn DS, Lee HY, Choi EJ, Kang BS
- KMID: 1123181
- Yonsei Med J.
- 1995 Jun;36(3):262-270.
- doi: 10.3349/ymj.1995.36.3.262
Mastoparan is an amphiphilic tetradecapeptide derived from wasp venom which activates G-proteins. Several secondary effects have been attributed to this peptide, including activation of phospholipase and phosphatidylinositol kinase. The aim... -
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- Involvement of throm box aneA2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation
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Rasheed H, Saeed SA
- KMID: 1097103
- Exp Mol Med.
- 2004 Jun;36(3):220-225.
The present study was carried out to examine the mechanisms of the synergistic interaction of PAF and A23187 mediated platelet aggregation. We found that platelet aggregation mediated by subthreshold concentrations... -
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- Anti-inflammatory effects of a Houttuynia cordata supercritical extract
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Shin S, Joo SS, Jeon JH, Park D, Jang MJ, Kim TO, Kim HK, Hwang BY, Kim KY, Kim YB
- KMID: 1093504
- J Vet Sci.
- 2010 Sep;11(3):273-275.
- doi: 10.4142/jvs.2010.11.3.273
Anti-inflammatory effects of Houttuynia cordata supercritical extract (HSE) were investigated in a carrageenan-air pouch model. HSE (200 mg/kg, oral) suppressed exudation and albumin leakage, as well as inflammatory cell infiltration.... -
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- Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine.
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Shah BH, Rasheed H, Rahman IH, Shariff AH, Khan FL, Rahman HB, Hanif S, Saeed SA
- KMID: 1457534
- Exp Mol Med.
- 2001 Dec;33(4):226-233.
Our recent studies have shown that co-activation of Gq and Gi proteins by 5-hydroxytryptamine (5-HT) and adrenaline show synergism in human platelet aggregation. This study was conducted to examine the... -
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- Effects of hypoxia on pulmonary vascular contractility
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Lee YH, Seo JH, Kang BS
- KMID: 711556
- Yonsei Med J.
- 1998 Jun;39(3):261-267.
- doi: 10.3349/ymj.1998.39.3.261
Although hypoxic pulmonary vasoconstriction (HPV) has been recognized by many researchers, the precise mechanism remains unknown. As isolated pulmonary arteries will constrict in vitro in the response to hypoxia, the... -
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- Mechanisms of relaxation of coronary artery by hypoxia
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Lee YH, Kim JT, Kang BS
- KMID: 711555
- Yonsei Med J.
- 1998 Jun;39(3):252-260.
- doi: 10.3349/ymj.1998.39.3.252
This study was designed to clarify the dependency of hypoxic coronary vasodilation (HCD) on the endothelium and the role of the K+ channels on HCD in the rabbit coronary artery.... -
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