- Recent Advances of Adoptive Immunotherapy to Prevent CMV Disease after Allogeneic Stem-cell Transplantation
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Park KD
- KMID: 2335718
- J Korean Pediatr Soc.
- 2003 May;46(5):418-422.
No abstract available. -
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- Brain Tumor Immunology: Part II : Immunotherapy of Malignant Brain Tumors
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Hong YK, Rha HK, Jung CK, Lee SW, Jo TH, Baik MW, Yoon SH, Kang JK, Song JU, Choi CR
- KMID: 2067857
- J Korean Neurosurg Soc.
- 1990 Dec;19(10-12):1389-1396.
The prognosis of patients with malignant brain tumors has improved only slightly despite the combined use of surgery, radiation therapy, and chemotherapy. Immunotherapy offers some possibilities and hopes as a... -
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- The immunobiology of cord blood transplantation
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Szabolcs P
- KMID: 2252032
- Korean J Hematol.
- 2010 Dec;45(4):224-235.
- doi: 10.5045/kjh.2010.45.4.224
Despite significant recent advances in the applicability and outcome following unrelated cord blood transplantation (UCBT), infections remain a major cause of mortality associated with poor immune recovery in the first... -
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- Adoptive Transfer of Colon Cancer Derived Peptide-specific CD8+ T Cells in HHD Mice
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Jung HS, Ahn IS, Do HK, Lemonnier , Tirosh B, Tzehoval E, Vadai E, Eisenbach , Do MS
- KMID: 2054241
- Immune Netw.
- 2004 Mar;4(1):31-37.
- doi: 10.4110/in.2004.4.1.31
BACKGROUND: 1-8D gene is a member of human 1-8 interferon inducible gene family and is shown to be overexpressed in fresh colon cancer tissues. Three peptides 1-6, 3-5 and 3-7... -
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- Adoptive Immunotherapy for Cytomegalovirus (CMV) Disease in Immunocompromised Patients
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Lim JB, Kwon OH, Kim HS, Kim HO, Choi JR, Provenzano M, Stroncek D
- KMID: 1726140
- Yonsei Med J.
- 2004 Jun;45(Suppl):S18-S22.
- doi: 10.3349/ymj.2004.45.Suppl.18
Cytomegalovirus (CMV) reactivation in immune compromised patients such as those undergoing hematopoietic progenitor cell transplantation (HPCT) and those with HIV infections can cause severe morbidity and mortality despite treatment with... -
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- Two Cases of Adjuvant Immunotherapy with Cytokine-Induced Killer Cells for Relapsed or Refractory Neuroblastoma
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Choi JY, An HY, Hong KT, Hong C, Kang HJ, Shin HY
- KMID: 2435416
- Clin Pediatr Hematol Oncol.
- 2018 Oct;25(2):202-207.
- doi: 10.15264/cpho.2018.25.2.202
The treatment outcomes of relapsed or refractory neuroblastoma have been unsatisfactory till date. We reported two cases of adoptive immunotherapy using cytokine-induced killer (CIK) cells against relapsed or refractory neuroblastoma.... -
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- Inhibition of Human Pancreatic Tumor Growth by Cytokine-Induced Killer Cells in Nude Mouse Xenograft Model
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Kim JS, Park YS, Kim JY, Kim YG, Kim YJ, Lee HK, Kim HS, Hong JT, Kim Y, Han SB
- KMID: 2150756
- Immune Netw.
- 2012 Dec;12(6):247-252.
- doi: 10.4110/in.2012.12.6.247
Pancreatic cancer is the fourth commonest cause of cancer-related deaths in the world. However, no adequate therapy for pancreatic cancer has yet been found. In this study, the antitumor activity... -
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- Understanding of molecular mechanisms in natural killer cell therapy
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Yoon SR, Kim TD, Choi I
- KMID: 2155406
- Exp Mol Med.
- 2015 Feb;47(2):e141.
- doi: 10.1038/emm.2014.114
Cancer cells and the immune system are closely related and thus influence each other. Although immune cells can suppress cancer cell growth, cancer cells can evade immune cell attack via... -
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- A Case of Management for Advanced Hepatocellular Carcinoma with Extrahepatic Metastasis by Autologous Natural Killer Cells Combined with Immune Checkpoint Inhibitor
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Woo A, Kim EJ, Shin SY, Jeon HJ, Park H, Chon YE, Lee YB, Hwang SG, Rim KS, Lee JH
- KMID: 2409651
- J Liver Cancer.
- 2018 Mar;18(1):67-74.
- doi: 10.17998/jlc.18.1.67
Hepatocellular carcinoma (HCC) has extremely poor prognosis. Immunotherapy has emerged as a new treatment for a number of cancers. Adoptive immunotherapy is one of the important cancer immunotherapy, which relies... -
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- Enhancement of Proliferation and Antigen Presentation of Human B Cells in Vitro by K562 Cells Expressing CD40L
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Park JY, Yoon SH, Kim EK, Yun SO, Sohn HJ, Kim TG
- KMID: 2150630
- Immune Netw.
- 2007 Jun;7(2):80-86.
- doi: 10.4110/in.2007.7.2.80
BACKGROUND: CD40-activated B (CD40-B) cells might be an attractive source of autologous antigen-presenting cells (APCs) for immunotherapy due to the convenience to obtain from peripheral blood and expand in vitro.... -
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- Differentiation induction of dendritic cell phenotypes from human leukemic cell lines
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Lee DH, Park JS, Eo WK, Kim WM, Kang K
- KMID: 1606842
- Korean J Physiol Pharmacol.
- 2001 Feb;5(1):79-86.
Recent clinical studies have shown that a high proportion of patients with acute promyelocytic leukemia (APL) achieve complete remission after treatment with all-trans retinoic acid (ATRA). However, most patients who receive continuous treatment... -
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- Lymphokine-activated killer(LAK) Cell Activity and Phenotypic Characterization in Peripheral Lymphocytes of Patients with Cervical Cancer
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Kim SR, Kim KT, Cho SH, Hwang YY, Lee JA, Moon H, Kim JM, Cho YJ
- KMID: 2083705
- Korean J Gynecol Oncol Colposc.
- 1992 Mar;3(1):10-23.
In adoptive immunotherapy of cancer using lymphokine-activated killer(LAK) cells indueed from patients own peripheral blood, the efficient cytotoxicity of LAK cells is a principal requirement. Peripheral blood lyrnphocytes were obtained... -
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- In vitro Culture of Dendritic Cells and Activation of Peripheral Blood Mononuclear Cells in Patients with Chronic Myelogenous Leukemia
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Park SY, Kim KW
- KMID: 1537191
- Korean J Hematol.
- 2000 Feb;35(1):50-56.
BACKGROUND: Dendritic cells (DCs) are professional antigen-presenting cells whose function is to present antigen to naive T cells and play a cental role in the induction of T- cell and... -
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- Ex vivo expansion of umbilical cord blood-derived T-lymphocyte with autologous cord blood plasma
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Lee SS, Sohn WS, Park HM, Kim YM, Mok JE
- KMID: 2128059
- Korean J Obstet Gynecol.
- 2005 Mar;48(3):607-616.
OBJECTIVE: The objective of this study was to establish a clinically applicable culture system by investigating the use of autologous cord blood plasma (ACBP) instead of fetal bovine serum (FBS)... -
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- The Anti-tumor Effect of Adoptive Immunotherapy with Dendritic Cells Cultured from the Bone Marrow in a Murine Squamous Cell Carcinoma Model
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Son YI, Kim KH, Sung MW, Beak CH, Chung SK, Chu KC, Seo IS
- KMID: 2274637
- Korean J Otolaryngol-Head Neck Surg.
- 2000 Feb;43(2):179-187.
BACKGROUND AND OBJECTIVES: It is known that patients with malignant tumor often have depressed antitumor immunity. Much information has been generated about a biologically-based therapy, which can induce or activate... -
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- Proliferation of CD4(+)CD25(high+)Foxp3(+) regulatory T lymphocytes in ex vivo expanded ascitic fluid from primary and recurrent ovarian carcinoma
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Lee SW, Kim YM, Lee HY, Kim DY, Kim JH, Nam JH, Kim YT
- KMID: 2173510
- J Gynecol Oncol.
- 2010 Mar;21(1):38-44.
- doi: 10.3802/jgo.2010.21.1.38
OBJECTIVE: Regulatory T lymphocytes evoke the immune tolerance by suppressing and inactivating cytotoxic T lymphocytes. The objective of this study was to compare the proportion of regulatory T lymphocytes, precisely... -
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- The Regulatory Effect of Tumor Necrosis Factor and Interleukin-2 on Tumor Infiltrating Lymphocytes from Renal Cell Carcinoma Patients
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Choi HY, Lee TY, Woo YN
- KMID: 1881258
- Korean J Urol.
- 1998 Jul;39(7):643-650.
PURPOSE: To increase the potency of TIL(tumor infiltrating lymphocytes) in immunotheraphy, the effect of TNF(tumor necrosis factor) and IL-2(interleukin-2) were investigated in vitro on proliferation and cytotoxic effect of TIL... -
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- In vitro induction of anterior gradient-2-specific cytotoxic T lymphocytes by dendritic cells transduced with recombinant adenoviruses as a potential therapy for colorectal cancer
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Lee HJ, Hong CY, Kim MH, Lee YK, Nguyen-Pham TN, Park BC, Yang DH, Chung IJ, Kim HJ, Lee JJ
- KMID: 1120143
- Exp Mol Med.
- 2012 Jan;44(1):60-67.
- doi: 10.3858/emm.2012.44.1.006
Anterior gradient-2 (AGR2) promotes tumor growth, cell migration, and cellular transformation, and is one of the specific mRNA markers for circulating tumor cells in patients with gastrointestinal cancer. We investigated... -
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- Enhancement of antitumor effect using dendritic cells activated with natural killer cells in the presence of Toll-like receptor agonist
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Pham TN, Hong CY, Min JJ, Rhee JH, Nguyen TA, Park BC, Yang DH, Park YK, Kim HR, Chung IJ, Kim HJ, Lee JJ
- KMID: 1078356
- Exp Mol Med.
- 2010 Jun;42(6):407-419.
- doi: 10.3858/emm.2010.42.6.042
Dendritic cells (DCs) play a role in natural killer (NK) cell activation, while NK cells are also able to activate and mature DCs. Toll-like receptors (TLRs) on the surface of... -
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- Epstein Barr virus-associated lymphoproliferative diseases: the virus as a therapeutic target
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Tse E, Kwong YL
- KMID: 2155401
- Exp Mol Med.
- 2015 Jan;47(1):e136.
- doi: 10.1038/emm.2014.102
Epstein Barr virus (EBV)-associated lymphoproliferative diseases (LPDs) express all EBV latent antigens (type III latency) in immunodeficient patients and limited antigens (type I and II latencies) in immunocompetent patients. Post-transplantation... -
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