- Cyclophosphamide dose: how much is needed to win the war against paraquat poisoning?
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Sun IO, Lee KY
- KMID: 1503777
- Korean J Intern Med.
- 2013 Jul;28(4):410-412.
- doi: 10.3904/kjim.2013.28.4.410
No abstract available. -
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- Selective inhibition of polymorphonuclear leukocytes by immunosuppressive concentration of prostaglandin E2
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Hong YS
- KMID: 932125
- J Korean Med Sci.
- 1996 Feb;11(1):8-16.
- doi: 10.3346/jkms.1996.11.1.8
Prostaglandin E2(PGE2) has been implicated as an immunosuppressive agent and plasma levels of PGE2 are elevated in patients sustaining thermal injury. We examined the effect of 10(-7) M prostaglandin E2(PGE2)... -
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- Short-term Efficacy of Topical Immunosuppressive Agents on the Survival of Cultivated Allo-Conjunctival Equivalents
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Shin YJ, Kim MK, Oh JY, Wee WR, Lee JH, Ko JH, Lee HJ, Lee JL, Min BM, Sohn YS
- KMID: 1099007
- Korean J Ophthalmol.
- 2008 Jun;22(2):123-129.
- doi: 10.3341/kjo.2008.22.2.123
PURPOSE: To investigate the short-term efficacy of topical immunosuppressive agents on the survival of cultivated allo-conjunctival equivalents. METHODS: Twenty-five eyes of New Zealand white rabbits were included. Temporal... -
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- Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense
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Shin EH, Kim TH, Hong SJ, Park JH, Guk SM, Chai JY
- KMID: 1080958
- Korean J Parasitol.
- 2003 Jun;41(2):81-87.
- doi: 10.3347/kjp.2003.41.2.81
The effects of anti-allergic drugs on intestinal mastocytosis and the expulsion of Neodiplostomum seoulense were observed in Sprague-Dawley rats, after oral infection with 500 metacercariae. The drugs used were hydroxyzine... -
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- Thalidomide Accelerates the Degradation of Extracellular Matrix in Rat Hepatic Cirrhosis via Down-Regulation of Transforming Growth Factor-beta1
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Lv P, Meng Q, Liu J, Wang C
- KMID: 2345885
- Yonsei Med J.
- 2015 Nov;56(6):1572-1581.
- doi: 10.3349/ymj.2015.56.6.1572
PURPOSE: The degradation of the extracellular matrix has been shown to play an important role in the treatment of hepatic cirrhosis. In this study, the effect of thalidomide on the... -
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- The dose of cyclophosphamide for treating paraquat-induced rat lung injury
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Choi JS, Jou SS, Oh MH, Kim YH, Park MJ, Gil HW, Song HY, Hong SY
- KMID: 1503779
- Korean J Intern Med.
- 2013 Jul;28(4):420-427.
- doi: 10.3904/kjim.2013.28.4.420
BACKGROUND/AIMS: Cyclophosphamide (CP) is a promising treatment for severe cases of paraquat (PQ) poisoning. We investigated the effective dose of CP for mitigating PQ-induced lung injury. METHODS: Adult male Sprague-Dawley rats... -
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- Deflazacort Increases Osteoclast Formation in Mouse Bone Marrow Culture and the Ratio of RANKL/OPG mRNA Expression in Marrow Stromal Cells
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Chung H, Kang YS, Hwang CS, Moon IK, Yim CH, Choi KH, Han KO, Jang HC, Yoon HK, Han IK
- KMID: 648360
- J Korean Med Sci.
- 2001 Dec;16(6):769-773.
- doi: 10.3346/jkms.2001.16.6.769
Information on precise effects of deflazacort on bone cell function, especially osteoclasts, is quite limited. Therefore, the present study was undertaken to test effects of deflazacort on osteoclast-like cell formation... -
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- The Role of Cyclosporine and Mycophenolate in an Orthotopic Porcine-to-Rat Corneal Xenotransplantation
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Lee HI, Kim MK, Oh JY, Ko JH, Lee HJ, Wee WR, Lee JH
- KMID: 1786890
- J Korean Med Sci.
- 2008 Jun;23(3):492-501.
- doi: 10.3346/jkms.2008.23.3.492
We performed this study to investigate the feature of rejection in porcine-to-rat corneal orthotopic transplantation and to evaluate the effect of cyclosporine and mycophenolate on the xeno-rejection. Orthotopic corneal transplantation... -
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- Rapamycin Inhibits Platelet-Derived Growth Factor- Induced Collagen, but Not Fibronectin, Synthesis in Rat Mesangial Cells
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Kim MS, Park J, Ha H, Kim YS, Kang SW, Jeong HJ, Kang DH, Yang CW
- KMID: 1726177
- Yonsei Med J.
- 2004 Dec;45(6):1121-1126.
- doi: 10.3349/ymj.2004.45.6.1121
Rapamycin, a macrocyclic lactone, is effective in reducing the incidence of acute rejection after renal transplantation. The inhibitory effects of rapamycin on lymphocyte proliferation and the molecular mechanisms that were... -
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- Cyclosporin A Inhibits Albumin Synthesis in Huh7 Cells
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Jeon YJ, Kim YS
- KMID: 1022171
- Korean J Intern Med.
- 2011 Sep;26(3):314-319.
- doi: 10.3904/kjim.2011.26.3.314
BACKGROUND/AIMS: Hypoalbuminemia occurs frequently in renal transplant recipients immediately after renal transplantation. We studied the regulation of hepatic albumin synthesis by cyclosporin A (CsA) in Huh7 cells. METHODS: Huh7 cells were... -
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- Comparison of Early and Late Conversion of Sirolimus in Experimental Model of Chronic Cyclosporine Nephropathy
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Kim JY, Ghee JY, Lim SW, Piao SG, Chung BH, Yoon HE, Hwang HS, Choi BS, Kim J, Yang CW
- KMID: 1120153
- J Korean Med Sci.
- 2012 Feb;27(2):160-169.
- doi: 10.3346/jkms.2012.27.2.160
Sirolimus (SRL) is a promising drug for replacing calcineurin inhibitors. We performed this study to determine the optimal time of conversion from cyclosporine (CsA) to SRL in an experimental model... -
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- Effects of cyclosporin A treatment on the pathogenesis of avian leukosis virus subgroup J infection in broiler chickens with Marek's disease virus exposure
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Kim Y, Brown TP, Pantin-Jackwood MJ
- KMID: 1089605
- J Vet Sci.
- 2003 Dec;4(3):245-255.
In this study, we investigated the effects of T-cell suppression on the pathogenesis of subgroup J avian leukosis virus (ALV-J). Chickens were treated with cyclosporin A (CSP) 50 mg/Kg body... -
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- Impact of Cyclosporin on Podocyte ZO-1 Expression in Puromycin Aminonucleoside Nephrosis Rats
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Kim BS, Park HC, Kang SW, Choi KH, Ha SK, Han DS, Lee HY
- KMID: 2158124
- Yonsei Med J.
- 2005 Feb;46(1):141-148.
- doi: 10.3349/ymj.2005.46.1.141
Puromycin aminonucleoside (PAN) -induced nephrosis is a well-described model of human idiopathic nephrotic syndrome, but the mechanism of PAN's effect is not completely understood. To investigate whether proteinuria in the... -
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- The effects of cyclophosphamide treatment on the pathogenesis of subgroup J avian leukosis virus (ALV-J) infection in broiler chickens with Marek's disease virus exposure
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Kim Y, Brown TP, Pantin-Jackwood MJ
- KMID: 1094687
- J Vet Sci.
- 2004 Mar;5(1):49-58.
Studies were performed to determine the effects of Bcell suppression on the pathogenesis of Subgroup J avian leukosis virus (ALV-J) in broiler chickens. Neonatal chickens were treated with cyclophosphamide (CY)... -
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