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Neonatal innate immunity and Toll-like receptor

Yoon HS

The innate immune response is the first line of defense against microbial infections. Innate immunity is made up of the surface barrier, cellular immunity and humoral immunity. In newborn, immunologic...
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Innate immunity in asthma

Kim HY

Asthma is a complex and heterogeneous disease with several phenotypes. Most studies have focused on allergic asthma associated with allergen sensitization and adaptive immunity. On the other hand, nonallergic asthma...
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Role of Innate Immunity in the Pathogenesis of Type 1 and Type 2 Diabetes

Lee MS

The importance of innate immunity in host defense is becoming clear after discovery of innate immune receptors such as Toll-like receptor or Nod-like receptor. Innate immune system plays an important...
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The Innate Immune Responses in Pathogenesis of Chronic Rhinosinusitis

Mo JH

Chronic rhinosinusitis (CRS) is a multifactorial and heterogeneous disease, and variousfactors, such as inflammation, infection, fungus, and superantigens, have been proposed to play crucial roles in its pathogenesis. Recently, the...
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Innate Immunity and Organ Transplantation

Yang CW

  • KMID: 1512740
  • Hanyang Med Rev.
  • 2006 Aug;26(3):48-53.
The immune response of transplanted grafts has been considered to be within the realm of the adaptive immune system. Recently, with the discovery of the Toll-like receptors (TLRs), the role...
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Role of Innate Immunity on the Asthma Immunopathogenesis

  • KMID: 2090083
  • Korean J Asthma Allergy Clin Immunol.
  • 2004 Jun;24(2):169-175.
No abstract available.
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Recent advance in primary immune deficiency disorders

Kang HJ, Shin HY, Ahn HS

The immune system is comprised of cells and molecules whose collective and coordinated response to the introduction of foreign substance is referred to as the immune response. Defense against microbes...
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The Gate Way of Communication between Microorganism and Human Body: Toll-like Receptors

Park JY, Han DS

  • KMID: 1647232
  • Korean J Gastroenterol.
  • 2002 Nov;40(5):287-293.
Innate immunity is the first line of defense against invading microorganisms and does not require the memory or lymphocytic clonal expansion. Toll-like receptors (TLRs) play an important role in this...
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Regulation of Innate Immunity via MHC Class II-mediated Signaling; Non-classical Role of MHC Class II in Innate Immunity

Park HL, Nam JH

MHC class II has long been known to play a classical role in antigen presentation and to act as a signal transducer capable of inducing the adaptive immunity needed to...
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Innate Immunity and Allergy

Kang JM

  • KMID: 2276745
  • Korean J Otolaryngol-Head Neck Surg.
  • 2007 May;50(5):376-384.
No Abstract available.
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The Role of Epithelium in the Pathophysiology of Chronic Rhinosinusitis : An Update

Min JY, Dhong HJ

  • KMID: 2297560
  • J Rhinol.
  • 2013 May;20(1):14-19.
Chronic rhinosinusitis (CRS) is characterized by persistent symptomatic inflammation of the nasal and paranasal sinus mucosa resulting from the interaction of multiple host and environmental factors. Although the etiology of...
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The Role of Type 2 Innate Lymphoid Cells in Allergic Diseases

  • KMID: 2299449
  • Korean J Asthma Allergy Clin Immunol.
  • 2012 Dec;32(4):207-212.
Innate lymphoid cells have recently been identified to be a cell population that has morphology typical of lymphocytes but lacks rearranged antigen receptors. It can be classified into RORgammat innate...
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The Role of Innate Immunity in Atopic Dermatitis and Asthma

  • KMID: 2299570
  • Korean J Asthma Allergy Clin Immunol.
  • 2009 Mar;29(1):1-9.
No abstract available.
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Innate Lymphoid Cells and Infection

Song CH

The functions of innate lymphoid cells (ILCs) have been known to play an important role in immunity and immune responses. ILCs are rapidly-responding cells that are involved in tissue remodeling,...
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Activation of Innate Immune System During Viral Infection: Role of Pattern-recognition Receptors (PRRs) in Viral Infection

Jun EJ, Kim YK

Innate immunity and adaptive immunity are two major immune responses against pathogens. Innate immunity is responsible for the immediate immune response to pathogens. Pattern-recognition receptors (PRRs) play an important role...
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Regulation of Intestinal Homeostasis by Innate Immune Cells

Kayama H, Nishimura , Takeda K

The intestinal immune system has an ability to distinguish between the microbiota and pathogenic bacteria, and then activate pro-inflammatory pathways against pathogens for host defense while remaining unresponsive to the...
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Antimicrobial Peptides in Innate Immunity against Mycobacteria

Shin DM, Jo EK

Antimicrobial peptides/proteins are ancient and naturallyoccurring antibiotics in innate immune responses in a variety of organisms. Additionally, these peptides have been recognized as important signaling molecules in regulation of both...
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Preeclampsia and Innate Immunity

Ahn H

  • KMID: 2280816
  • Korean J Perinatol.
  • 2011 Jun;22(2):81-87.
Preeclampsia(PE) remains a leading cause of maternal and fetal morbidity and mortality. Despite decades of intense research on the problem, there is no early pregnancy screening test to recognize those...
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Toll-like Receptors and Innate Immunity

Yuk JM, Jo EK

Toll-like receptors (TLRs) are the best-characterized membrane-bound receptors in innate immune cells, including macrophages and dendritic cells. Upon recognition of specific ligands originating from pathogen- and modified self-derived molecules, TLRs...
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Mucosal vaccine adjuvants update

Rhee JH, Lee SE, Kim SY

Mucosal vaccination, capable of inducing protective immune responses both in the mucosal and systemic immune compartments, has many advantages and is regarded as a blue ocean in the vaccine industry....
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