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Outstanding Features of COVID-19 Overlapping Primary Immunodeficiency in Children

Jiang Q, Yang Q, Niu MM, Hu P

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Comparison of Waning Immunity Between Booster Vaccination and 2-Dose Vaccination With BNT162b2

Jung J, Kim JY, Kwon JS, Yun SC, Kim SH

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Omicron Subvariants, Including BA.4 and BA.5, Substantially Preserve T Cell Epitopes of Ancestral SARS-CoV-2

Park K, Choi SJ, Shin EC

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Why Should We Consider Potential Roles of Oral Bacteria in the Pathogenesis of Sjögren Syndrome?

Chang SH, Park SH, Cho ML, Choi Y

Sjögren syndrome (SS) is a chronic autoimmune disorder that primarily targets the salivary and lacrimal glands. The pathology of these exocrine glands is characterized by periductal focal lymphocytic infiltrates, and...
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Dexamethasone, but Not Vitamin D or A, Dampens the Inflammatory Neutrophil Response to Protect Atrisk COVID-19 Patients

Hafkamp FM, Mol S, Waqué I, Jong ECD

Dexamethasone (DEX) was the first drug shown to save lives of critically ill coronavirus disease 2019 (COVID-19) patients suffering from respiratory distress. A hyperactivated state of neutrophils was found in...
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SOCS3 Attenuates DexamethasoneInduced M2 Polarization by DownRegulation of GILZ via ROS- and p38 MAPK-Dependent Pathways

Jeong H, Yoon H, Lee Y, Kim JT, Yang M, Kim G, Jung B, Park SH, Lee CE

Suppressors of cytokine signaling (SOCS) have emerged as potential regulators of macrophage function. We have investigated mechanisms of SOCS3 action on type 2 macrophage (M2) differentiation induced by glucocorticoid using...
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Tobacco Smoking Could Accentuate Epithelial-Mesenchymal Transition and Th2-Type Response in Patients With Chronic Rhinosinusitis With Nasal Polyps

Lee KI, Han Y, Ryu JS, In SM, Kim JY, Park JS, Kim JS, Kim J, Youn J, Park SR

Tobacco smoking (TS) has been known as one of the most potent risk factors for airway inflammatory diseases. However, there has been a paucity of information regarding the immunologic alteration...
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Vitamin D Attenuates Pain and Cartilage Destruction in OA Animals via Enhancing Autophagic Flux and Attenuating Inflammatory Cell Death

Jhun J, Woo JS, Kwon JY, Na HS, Cho KH, Kim SA, Kim SJ, Moon SJ, Park SH, Cho ML

Osteoarthritis (OA) is the most common form of arthritis associated with ageing. Vitamin D has diverse biological effect on bone and cartilage, and observational studies have suggested it potential benefit...
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