- Immune Responses to Viral Infection
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Hwang ES, Park CG, Cha CY
- KMID: 1637945
- Immune Netw.
- 2004 Jun;4(2):73-80.
- doi: 10.4110/in.2004.4.2.73
Viruses are obligate intracellular parasites which cause infection by invading and replicating within cells. The immune system has mechanisms which can attack the virus in extracellular and intracellular phase of... -
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- Adenosine Blockage in Tumor Microenvironment and Improvement of Cancer Immunotherapy
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Arab S, Hadjati J
- KMID: 2455933
- Immune Netw.
- 2019 Aug;19(4):e23.
- doi: 10.4110/in.2019.19.e23
Immunotherapy has been introduced into cancer treatment methods, but different problems have restricted the efficacy of these protocols in clinical trials such as the presence of various immunomodulatory factors in... -
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- The CD28-B7 Family in Anti-Tumor Immunity: Emerging Concepts in Cancer Immunotherapy
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Leung J, Suh WK
- KMID: 2150817
- Immune Netw.
- 2014 Dec;14(6):265-276.
- doi: 10.4110/in.2014.14.6.265
The interactions between B7 molecules and CD28-family receptors are crucial in the regulation of adaptive cellular immunity. In cancer, the aberrant expression of co-inhibitory B7 molecules has been attributed to... -
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- Mechanism of Allergic Asthma Pathogenesis by Protease Allergen
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Lee SH
- KMID: 2168219
- Hanyang Med Rev.
- 2013 Feb;33(1):39-44.
- doi: 10.7599/hmr.2013.33.1.39
Asthma is a complex immune mediated chronic inflammatory lung disease characterized by chronic inflammation of the airways, airway hyper-responsiveness and airway obstruction, and the prevalence of this disease has increased... -
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- Innate immune response to oral bacteria and the immune evasive characteristics of periodontal pathogens
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Ji S, Choi Y
- KMID: 1783671
- J Periodontal Implant Sci.
- 2013 Feb;43(1):3-11.
- doi: 10.5051/jpis.2013.43.1.3
Periodontitis is a chronic inflammation of periodontal tissue caused by subgingival plaque-associated bacteria. Periodontitis has long been understood to be the result of an excessive host response to plaque bacteria.... -
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- Virulence factors of Helicobacter pylori and their clinical significances
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Lee YC
- KMID: 1523321
- Hanyang Med Rev.
- 2007 Aug;27(3):28-33.
Helicobacter pylori (H. pylori) is known be an etiologic factor for gastric and duodenal ulcer, gastric noncardiac adenocarcinoma, and MALT lymphoma in a subset of infected individuals. Pathogenesis of H.... -
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- Insight into the Pathogenesis of Lyme Disease
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Shin OS
- KMID: 2135353
- J Bacteriol Virol.
- 2014 Mar;44(1):10-22.
- doi: 10.4167/jbv.2014.44.1.10
Lyme disease is the most common vector-borne disease in the United States and Europe, caused by a tick-borne spirochete, Borrelia burgdorferi. Life cycle alternation between arthropod and mammals enhanced B.... -
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- Single-Cell Sequencing in Cancer: Recent Applications to Immunogenomics and Multi-omics Tools
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Sierant MC, Choi J
- KMID: 2439207
- Genomics Inform.
- 2018 Dec;16(4):e17.
- doi: 10.5808/GI.2018.16.4.e17
Tumor heterogeneity, the cellular mosaic of multiple lineages arising from the process of clonal evolution, has continued to thwart multi-omics analyses using traditional bulk sequencing methods. The application of single-cell... -
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- N-Linked Glycosylation in the Hemagglutinin of Influenza A Viruses
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Kim JI, Park MS
- KMID: 2453944
- Yonsei Med J.
- 2012 Sep;53(5):886-893.
Since the 1918 influenza A virus (IAV) pandemic, H1N1 viruses have circulated in human populations. The hemagglutinin (HA) of IAV determines viral antigenicity and often undergoes N-linked glycosylation (NLG) at... -
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- miR-195/miR-497 Regulate CD274 Expression of Immune Regulatory Ligands in Triple-Negative Breast Cancer
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Yang L, Cai Y, Zhang D, Sun J, Xu C, Zhao W, Jiang W, Pan C
- KMID: 2429815
- J Breast Cancer.
- 2018 Dec;21(4):371-381.
- doi: 10.4048/jbc.2018.21.e60
PURPOSE: Immune suppression is common in patients with advanced breast cancer but the mechanisms underlying this phenomenon have not been sufficiently studied. In this study, we aimed to identify B7... -
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- Loss of Human Leukocyte Antigen Class I Expression Is Associated with Poor Prognosis in Patients with Advanced Breast Cancer
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Park HS, Cho U, Im SY, Yoo CY, Jung JH, Suh YJ, Choi HJ
- KMID: 2465446
- J Pathol Transl Med.
- 2019 Mar;53(2):75-85.
- doi: 10.4132/jptm.2018.10.11
BACKGROUND: Human leukocyte antigen class I (HLA-I) molecules play important roles in regulating immune responses. Loss or reduction of HLA-I expression has been shown to be associated with prognosis in... -
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- Role of Immunosuppressive Microenvironment in Acquiring Immunotolerance Post-Photothermal Therapy
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Cherukula , Park MS, Sontyana A, Mathew AP, Vijayan V, Bae WK, Park IK
- KMID: 2462185
- J Korean Med Sci.
- 2019 Nov;34(44):e272.
- doi: 10.3346/jkms.2019.34.e272
BACKGROUND: Nanoparticle-mediated photothermal therapy (PTT) has been well studied as a treatment for cancer. However, the therapeutic outcome of PTT is often hindered by the penetration depth of laser light.... -
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- Characterization of Pv92, a Novel Merozoite Surface Protein of Plasmodium vivax
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Lee SK, Wang B, Han JH, Nyunt MH, Muh F, Chootong P, Ha KS, Park WS, Hong SH, Park JH, Han ET
- KMID: 2353566
- Korean J Parasitol.
- 2016 Aug;54(4):385-391.
- doi: 10.3347/kjp.2016.54.4.385
The discovery and understanding of antigenic proteins are essential for development of a vaccine against malaria. In Plasmodium falciparum, Pf92 have been characterized as a merozoite surface protein, and this... -
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