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Investigation into the Effects of Mosapride on Motility of Guinea Pig Stomach, Ileum, and Colon

Ji SW, Park HJ, Cho JS, Lim JH, Lee SI

Mosapride citrate (Mosapride) is a new prokinetic agent that enhances the gastrointestinal (GI) motility by stimulation of 5-HT4 receptors. This agent stimulates acetylcholine release from enteric cholinergic neurons in the...
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Effect of Itopride Hydrochloride on the Ileal and Colonic Motility in Guinea Pig In Vitro

Lim HC, Kim YG, Lim JH, Kim HS, Park H

PURPOSE: Itopride hydrochloride (itopride) inhibits acetylcholinesterase (AChE) and antagonizes dopamine D(2) receptor, and has been used as a gastroprokinetic agent. However, its prokinetic effect on the small bowel or colon...
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