- Perinatal brain damage caused by cerebral hypoxia-ischemia
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Shin SM
- KMID: 1690685
- J Korean Pediatr Soc.
- 1993 Jan;36(1):1-8.
No abstract available. -
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- E-selectin Mrna and Protein Expression Increase Transiently After Unilateral Cerebral hypoxia-ischemia in Neonatal Rats
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Eun BL
- KMID: 2177120
- J Korean Child Neurol Soc.
- 1998 May;5(2):228-234.
BACKGROUND AND PURPOSE: The selectins play a role in the initiation of endothelium-leukocyte interaction; endothelial expression of E-selectin is induced by ischemia-reperfusion-like conditions in vitro. Neutrophils accumulate in post-hypoxic-ischemic neonatal... -
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- Therapeutic Effect of Nimodipine in Neonatal Rat Model of Cerebral Hypoxia-Ischemia
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Hong IH, Kim HM
- KMID: 2207695
- J Korean Pediatr Soc.
- 1999 Nov;42(11):1552-1558.
PURPOSE: Recent studies suggest that nimodipine, a potent calcium-channel blocker, may improve neurological outcome after experimental hypoxia-ischemic brain injury. This study was conducted to evaluate the therapeutic effect of nimodipine... -
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- Effect of Vitamin E on Cerebral Hypoxia-Ischemia in Neonatal Rats
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Seok JE, Oh YK, Park ST
- KMID: 1946204
- J Korean Pediatr Soc.
- 2001 Jul;44(7):764-772.
PURPOSE: In order to evaluate the hypoxia-ischemia induced neurotoxic effect and the protective effect of vitamin E as an antioxidant, cell number and cell viability were measured in cerebral neurons... -
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- Prolonged Delirium Secondary to Hypoxic-ischemic Encephalopathy Following Cardiac Arrest
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Yogaratnam J, Jacob R, Naik S, Magadi H, Sim K
- KMID: 2171196
- Clin Psychopharmacol Neurosci.
- 2013 Apr;11(1):39-42.
Hypoxic-ischemic brain injury encompasses a complex constellation of pathophysiological and cellular brain injury induced by hypoxia, ischemia, cytotoxicity, or combinations of these mechanisms and can result in poor outcomes including... -
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- The Neuroprotective Effects of the Platelet-Activating Factor Antagonist BN 52021 on Hypoxic-ischemic Brain Injury in the Immature Rat
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Eun BL
- KMID: 2329201
- J Korean Child Neurol Soc.
- 1997 Oct;5(1):9-22.
PURPOSE: Platelet-activating factor (PAF) is overproduced in ischemic brain. Although post-ischemic PAF antagonist administration protects the mature brain in some models, little is known about the effects of PAF antagonists... -
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- Effect of Resuscitation with High Concentration Oxygen on a Rat Model of Neonatal Hypoxic-Ischemic Brain Injury
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Lee DS, Kwak SH, Kim HM, Sohn YK
- KMID: 1829880
- J Korean Pediatr Soc.
- 2001 Nov;44(11):1278-1288.
PURPOSE: This study was undertaken to determine whether any features of apoptosis would occur in the established model of cerebral hypoxia-ischemia in neonatal rats. It was also undertaken to evaluate... -
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- NeuroRehabilitation after Hypoxic-ischemic Encephalopathy
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Leigh JH, Oh BM
- KMID: 1914555
- Brain Neurorehabil.
- 2014 Mar;7(1):16-20.
- doi: 10.12786/bn.2014.7.1.16
The number of survivors after hypoxic-ischemic encephalopathy has been increasing due to recent progress in medical system and care. Impairment after injury ranges from mild memory deficit to vegetative state... -
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- Effect of hypothermia on brain cell membrane function and energy metabolism after transient global hypoxia-ischemia in the newborn piglet
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Park WS, Chang YS, Lee MH
- KMID: 1129907
- J Korean Med Sci.
- 2001 Jun;16(3):335-341.
- doi: 10.3346/jkms.2001.16.3.335
This study was done to determine the effects of hypothermia on brain cell membrane function and energy metabolism after transient hypoxia-ischemia (HI) in the newborn piglet. Cerebral HI was induced... -
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- Protective Effect of Hypoxic Preconditioning on Hypoxic-Ischemic Injured Newborn Rats
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Park HK, Seol IJ, Kim KS
- KMID: 1123451
- J Korean Med Sci.
- 2011 Nov;26(11):1495-1500.
- doi: 10.3346/jkms.2011.26.11.1495
Brief episodes of cerebral hypoxia-ischemia cause transient ischemic tolerance to subsequent ischemic events that are otherwise lethal. This study was conducted to evaluate the protective effect of hypoxic preconditioning on... -
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- Initiation of Therapeutic Hypothermia with a Cooling Fan for an Asphyxiated Newborn
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Lee SH, Jang WJ, Cho HJ, Cho KH, Shim SY, Son DW
- KMID: 2188324
- J Korean Soc Neonatol.
- 2012 Nov;19(4):269-274.
- doi: 10.5385/jksn.2012.19.4.269
Induced hypothermia for newborns with hypoxic-ischemic encephalopathy results in a significant decrease in mortality and neurodevelopmental disability. For optimal neuroprotection following perinatal hypoxia-ischemia (HI), therapy should begin within 6 hrs... -
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- Neuroprotective effects of tanshinone I from Danshen extract in a mouse model of hypoxia-ischemia
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Lee JC, Park JH, Park OK, Kim IH, Yan BC, Ahn JH, Kwon SH, Choi JH, Kim JD, Won MH
- KMID: 2263144
- Anat Cell Biol.
- 2013 Sep;46(3):183-190.
- doi: 10.5115/acb.2013.46.3.183
Hypoxia-ischemia leads to serious neuronal damage in some brain regions and is a strong risk factor for stroke. The aim of this study was to investigate the neuroprotective effect of... -
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- Hypothermia Therapy in Neonatal Hypoxic Ischemic Encephalopathy
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Lee SL
- KMID: 2071997
- Korean J Perinatol.
- 1999 Dec;10(4):447-452.
No abstract available. -
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- Expression of P-selectin mRNA and Protein on Hypoxic-Ischemic Brain Injury in Neonatal Rat
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Kim KB, Lim JH, Pee DH, Eun BL, Tockgo YC
- KMID: 2137162
- J Korean Child Neurol Soc.
- 2001 May;9(1):59-68.
PURPOSE: The selectin family of adhesion molecules plays a role in the initiation of endothelium-leukocyte interaction of inflammation and ischemia-reperfusion. P-selectin, a rapidly expressed endothelial cell adhesion molecule, is essential... -
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- Therapeutic Hypothermia for Newborns with Hypoxic Ischemic Encephalopathy
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Chang M
- KMID: 2052449
- Neonatal Med.
- 2013 Feb;20(1):2-11.
- doi: 10.5385/nm.2013.20.1.2
Brain injury secondary to hypoxia-ischemia (HI) is one of the major causes of neonatal death and severe, long-term neurologic deficits in children. Aside from hypothermia, no established therapies exist. Although... -
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- The Effect of Pentoxifylline on IL-1beta and TNF-alpha mRNA Gene Expression in Hypoxic-Ischemic Brain Injury of Immature Rat
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Kim KB, Jeon GH, Kim YR, Lee JH, Lee KH, Eun BL, Kim SK
- KMID: 2007257
- J Korean Child Neurol Soc.
- 1999 Dec;7(2):181-187.
PURPOSE: Interleukin-1beta(IL-1beta) and Tumor necrosis factor-alpha(TNF-alpha) are multifunctional cytokines that may play important roles both in the normal development of central nervous system and in the response of brain to... -
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- Neuroprotective Effect of Cycloheximide on Hypoxic-Ischemic Brain Injury in Neonatal Rats
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Park WS, Sung DK, Kang S, Koo SH, Kim YJ, Lee JH, Chang YS, Lee M
- KMID: 1781846
- J Korean Med Sci.
- 2006 Apr;21(2):337-341.
- doi: 10.3346/jkms.2006.21.2.337
This study was done to determine the neuroprotective effect of cycloheximide on neonatal hypoxic-ischemic brain injury. Seven day-old newborn rat pups were subjected to 90 min of 8% oxygen following... -
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- Effects of 7-Nitroindazole on Brain Cell Membrane Function and Energy Metabolism during Transient Global Cerebral Hypoxia-Ischemia and Reoxygenation-Reperfusion in Newborn Piglets
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Choi CW, Hwang JH, Chang YS, Park WS
- KMID: 2278889
- Korean J Pediatr.
- 2004 Feb;47(2):204-209.
PURPOSE: Our study was undertaken to discover whether a selective neuronal nitric oxide synthase inhibitor, 7-nitroindazole, influences brain cell membrane function and energy metabolism during and after transient global hypoxia-ischemia(HI)... -
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- Therapeutic Window for Cycloheximide Treatment after Hypoxic-Ischemic Brain Injury in Neonatal Rats
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Park WS, Sung DK, Kang S, Koo SH, Kim YJ, Lee JH, Chang YS, Lee M
- KMID: 1778434
- J Korean Med Sci.
- 2006 Jun;21(3):490-494.
- doi: 10.3346/jkms.2006.21.3.490
We have previously shown that cycloheximide significantly inhibited apoptosis, and reduced ensuing cerebral infarction in a newborn rat model of cerebral hypoxiaischemia. This study was performed to determine the therapeutic... -
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- Management of Hypoxic-Ischemic Encephalopathy: Present and Future
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Kim WT
- KMID: 1838158
- Korean J Perinatol.
- 2003 Dec;14(4):393-399.
No abstract available. -
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