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Severe Hypophosphatemia in a Girl with Systemic Lupus Erythematosus

Lim TJ, Kim SY, Kim SH

Systemic lupus erythematosus (SLE) is characterized by various symptoms and multi-organ involvement. Hypophosphatemia has been described in several diseases accompanied with systemic inflammation. However, hypophosphatemia has rarely been described in...
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Carpal Spasm in a Patient with Hypophosphatemia

Lee SH, Shim YJ, Choi JH, Kim HS

Phosphate is an essential ion and plays a vital role in many physiological processes. Carpopedal spasm is known as a symptom of hypocalcemia, or rarely, hypomagnesemia. We present an unusual...
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Severe hypophosphatemia in hospitalized patients

Kang SJ, Kim JY, Park HJ, Han DH, Yu BH, Moon SS

  • KMID: 1695113
  • Korean J Nephrol.
  • 1991 Oct;10(3):330-335.
No abstract available.
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Late and Insufficient Phosphorus Supplementation is Associated with Early Severe Hypophosphatemia in Extremely Low Birth Weight Infants with Early Amino Acid Administration

Yang SM, Noh OK, Lee JH, Park MS

OBJECTIVE: To investigate the incidence of early severe hypophosphatemia, and examine the associated clinical factors and outcomes, in extremely low birth weight infants (ELBWI) who received early amino acid administration. METHODS:...
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A Case of Osteosarcoma induced Oncogenic Osteomalacia Detected by MRI

Lim SK, Song YD, Lee HC, Huh KB, Park KH, Kim KR, Hong SW, Nam JH, Yook JI, Choi BJ, Kim MK, Shin KH

  • KMID: 2199472
  • J Korean Soc Endocrinol.
  • 1999 Jun;14(2):401-409.
Oncogenic osteomalacia is a syndrome characterized by phosphaturia, hypophosphatemia, decreased 1,25-dihydroxyvitamin D level and specific signs and symptoms of osteomalacia. It is associated with the presence of neoplasm originated from...
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Respiratory failure in a diabetic ketoacidosis patient with severe hypophosphatemia

Choi HS, Kwon A, Chae HW, Suh J, Kim DH, Kim HS

Phosphate is essential in regulating human metabolic processes, and severe hypophosphatemia can induce neurologic and hematological complications and result in respiratory failure and cardiac dysfunction. Therefore, correction of severe hypophosphatemia...
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Three Cases of Osteomalacia with Fractures Induced by Adefovir in Chronic Hepatitis B

Kim AR, Choi YJ, Chung YS

Adefovir dipivoxil is used antiviral agent in the treatment of chronic hepatitis B virus infection. This drug is recommended for patients infected with lamivudine-refractory hepatitis B. Many studies of low-dose...
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Oncogenic Osteomalacia with Multiple Insufficiency Fractures: A Case Report

Park YC, Seo JO, Yang KH

Oncogenic osteomalacia is a rare paraneoplastic syndrome, characterized by hypophosphatemia, renal phosphate wasting, osteomalacia, and multiple insufficiency fractures, as a result of the tumor. A wide excision of the causative...
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A case of Fanconi syndrome

Lee YW, Lim IS, Kim CH

  • KMID: 1945955
  • J Korean Pediatr Soc.
  • 1993 May;36(5):737-742.
Fanconi syndrome is a complex of renal tubular dysfunction defined by glycosuria without diabetes, generalized aminoaciduria, phosphaturia, bicarbonaturia, uric aciduria, and renal tubular acidosis. It is often associated with hypokalemia,...
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Refeeding Syndrome Associated with Delusion in a Schizophrenic Patient

Ha JW, Kwon YD, Lim SW

  • KMID: 2029211
  • Korean J Biol Psychiatry.
  • 2008 Aug;15(3):219-223.
Refeeding syndrome is a life-threatening but treatable condition occurring in any patients with starvation. Electrolyte imbalance, especially hypophosphatemia and fluid shift result in metabolic changes in various systems. The authors...
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Association between Hypophosphatemia and Cardiac Arrhythmias in the Early Stage of Sepsis: Could Phosphorus Replacement Treatment Reduce the Incidence of Arrhythmias?

Schwartz A, Brotfain E, Koyfman L, Kutz R, Gruenbaum , Klein M, Zlotnik A

It is well known that new-onset arrhythmias are common in septic patients. It is thought that hypophosphatemia in the early stages of sepsis may contribute to the development of new...
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Severe Hypophosphatemia-Induced Acute Toxic-Metabolic Encephalopathy in Continuous Renal Replacement Therapy

Han SA, Park HY, Kim HW, Choi JI, Kang DY, Kim HL, Chung JH, Shin BC

Acute toxic-metabolic encephalopathy (TME) is an acute condition of global cerebral dysfunction in the absence of primary structural brain disease. Severe hypophosphatemia leads to muscle weakness and involves the diaphragm...
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A Case of Osteomalacia Related to Adefovir in a Patient with Chronic Hepatitis B

Ahn SY, Ko SY, Jang YM, Choi YH, Kim BK, Choe WH, Lee CH, Kwon SY

Adefovir dipivoxil, an acyclic nucleoside analogue, has been approved for the treatment of patients with chronic hepatitis B. This agent is efficacious particularly in those who have developed lamivudine resistance....
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A case of severe hypophosphatemia related to adefovir dipivoxil treatment in a patient with liver cirrhosis related to hepatitis B virus

Lee HJ, Choi JW, Kim TN, Eun JR

Adefovir dipivoxyl (ADV) effectively suppresses hepatitis B virus (HBV) replication but exhibits nephrotoxicity with severe hypophosphatemia when administered at a high dosage. This is the first report of severe hypophosphatemic...
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Dental management of patients with X-linked hypophosphatemia

Lee BN, Jung HY, Chang HS, Hwang YC, Oh WM

X-linked hypophosphatemia (XLH) is a hereditary metabolic disease caused by the loss of phosphate through the renal tubules into the urine, and an associated decrease in serum calcium and potassium...
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The influence of hypophosphatemia on outcomes of low- and high-intensity continuous renal replacement therapy in critically ill patients with acute kidney injury

Kim SY, Kim YN, Shin HS, Jung Y, Rim H

BACKGROUND: The purpose of this study was to assess the role of hypophosphatemia in major clinical outcomes of patients treated with low- or high-intensity continuous renal replacement therapy (CRRT). METHODS: We...
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Case of Thyrotoxic Periodic Paralysis Accompanied by Atrioventricular Block Associated with Hypokalemia and Hypophosphatemia

Kim HS, Wi JK, So JI, Choi MC, Chon S, Oh S, Woo JT, Kim SW, Kim JW, Kim YS

  • KMID: 2332992
  • J Korean Soc Emerg Med.
  • 2011 Oct;22(5):570-574.
Thyrotoxic periodic paralysis (TPP) occurs in 2% of the asian patients with hyperthyroidism and is characterized by bilateral flaccid paralysis of the extremity, especially lower limbs. It is well-known that...
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A FGF23-Positive Maxillary Sinus Tumor Associated with Oncogenic Osteomalacia

Kim NH, Kim JH, Kwon JH, Kim KS

  • KMID: 2297584
  • J Rhinol.
  • 2012 May;19(1):70-73.
Oncogenic osteomalacia is a rare acquired paraneoplastic syndrome caused by excessive renal phosphate wasting that causes hypophosphatemia and osteomalacia. Fibroblast growth factor 23 (FGF23) has been identified as the causative...
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A Case of Late-Onset Hypophosphatemic Ricket

Shin GM, Yi SD, Park YC

  • KMID: 1957565
  • J Korean Neurol Assoc.
  • 1987 Dec;5(2):249-254.
Late onset hypophosphatemic ricket is a nonfamilial sporadic disease characterized by clinical manitestations of ricket and proximal muscle weakness in the adolescence or adulthood without previous history of ricket. The...
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Two Cases of Hypophosphatemic Osteomalacia After Long-term Low Dose Adefovir Therapy in Chronic Hepatitis B and Literature Review

Jeong HJ, Lee JM, Lee TH, Lee JY, Kim HB, Heo MH, Choi G, Chae JN, Kim JM, Kim SH, Kwon KY

  • KMID: 2391956
  • J Bone Metab.
  • 2014 Feb;21(1):76-83.
Adefovir dipivoxil (ADV) is a nucleotide used as long-term therapy of chronic hepatitis B. Many published reports have shown that long-term high-dose therapy with adefovir can be associated with proximal...
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