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Hydromorphone attenuates intercellular adhesion molecule-1 expressions induced by lipopolysaccharide on HCT-116 human colon cancer cells

Lee JJ, Kim WY, Um JH, Min TJ

No abstract available.
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The Efficacy and Incidence of Side Effects in Patient Controlled Analgesia Using Hydromorphone

Oh AY, Park YO, Jeon YT, Jung MW, Lee HK, Oh YS

BACKGROUND: Hydromorphone, a derivative of morphine, has the same actions and uses as morphine, has about eight times more potency on a milligram basis. Hydromorphone is used for the relief...
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A Comparison of Hydromorphone-Bupivacaine and Fentanyl-Bupivacaine in Patient Controlled Epidural Analgesia after Thoracotomy

Sim WS, Yeo JS

BACKGROUND: Hydromorphone has an intermediate lipid solubility range that falls between morphine and fentanyl. Lipophilic activity during opioid epidural administration is important in relation to both the side effects and...
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Emergency Department-Based Treatment of Acute Ureteral Colic with Hydromorphone and Pethidine: Prospective, Randomized Control Trial

Choi WJ, Kim WY, Sohn CH, Ryu JM, Seo DW, Lee JH, Lee YS, Oh BJ, Kim W, Lim KS

  • KMID: 2332900
  • J Korean Soc Emerg Med.
  • 2011 Apr;22(2):151-155.
PURPOSE: To compare the efficacies and side effects of intravenous hydromorphone and pethidine in the emergency department (ED) treatment of ureteral colic. METHODS: A prospective, controlled, randomized clinical trial was conducted...
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Efficacy and Tolerability of OROS Hydromorphone in Strong Opioid-Naive Patients: An Open Label, Prospective Study

Hwang JE, Kim DE, Kim HN, Yoon JY, Bae WK, Shim HJ, Cho SH, Chung IJ

  • KMID: 2258999
  • Korean J Med.
  • 2011 Mar;80(3):317-322.
BACKGROUND/AIMS: OROS hydromorphone is a synthetic opioid agent. While clinical studies have tested its effectiveness at controlling cancer-associated pain in patients who have received other strong opioids, no clinical studies...
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The effects of hydromorphone on astrocytic responses in cerebral ischemia

Lee CH, Park YC, Kim JH, Kim WY, Lee YS, Kim YH, Min TJ

BACKGROUND: Ischemic insult during operation could cause ischemic-reperfusion injuries in brain and memory impairments. Total intravenous anesthesia (TIVA) is preferred in brain surgery to promote the use of motor evoked...
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Comparison of hydromorphone and fentanyl administered by lumbar epidural as patient-controlled analgesia after total knee arthroplasty

Jung MG, Park JB, Jang YH, Ahn EK, Lee JH

  • KMID: 2046801
  • Anesth Pain Med.
  • 2009 Jul;4(3):230-234.
BACKGROUND:Hydromorphone is a semi-synthetic opioid that has recently been used for the control of acute and chronic pain.It has been reported that epidural infusion of hydromorphone provides rapid onset of...
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Effects of Epidural Naloxone on Pruritus Induced by Hydromorphone Epidural Patient-Controlled Analgesia

Bang SR, Kim HS, Kim JH, Sim WS, Gwak MS, Yang MK, Kim CS, Hahm TS, Cho HS, Choi DH, Kim TH

BACKGROUND: Opioid delivered by epidural patient-controlled analgesia (PCA) is effective in relieving pain after surgery, but it is associated with side effects, such as nausea, vomiting, pruritus, respiratory depression, and...
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Effect of ketamine on intravenous patient-controlled analgesia using hydromorphone and ketorolac after the Nuss surgery in pediatric patients

Min TJ, Kim WY, Jeong WJ, Choi JH, Lee YS, Kim JH, Park YC

BACKGROUND: Nuss surgery is preferred in pectus excavatum repair because this procedure produces excellent cosmetic results and prevents postoperative distressed pulmonary function. However, the procedure causes severe pain due to...
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Once-Daily OROS Hydromorphone for Management of Cancer Pain: an Open-Label, Multi-Center, Non-Interventional Study

Park CK, Kang HW, Oh IJ, Kim YC, Kim YK, Na KJ, Ahn SJ, Kim TO, Choi YJ, Song GA, Lee MK

Extended-release osmotic extended-release oral delivery system (OROS) hydromorphone is a strong synthetic opioid designed to maintain a constant blood concentration by once daily dosing. The objective of this observational study...
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Clinical benefits of preemptive thoracic epidural analgesia with hydromorphone and bupivacaine in open thoracotomy lung surgery

Lee SH, Sim WS, Yang M, Kim JA, Ahn HJ, Shin BS, Lim HY, Kim DY, Yoon JS

BACKGROUND: Preemptive analgesia is known to decrease the sensitization of the central nervous system and reduce subsequent amplification of nociceptive stimuli. We investigated whether preemptive thoracic epidural analgesia (TEA) demonstrated...
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Breakthrough Cancer Pain

Seo MS, Shim JY

Breakthrough cancer pain is a transient exacerbation of pain that occurs despite relatively well controlled background pain with around-the-clock analgesia. It is highly prevalent in patients with cancer pain, with...
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Current Evidence for Spinal Opioid Selection in Postoperative Pain

Bujedo BM

BACKGROUND: Spinal opioid administration is an excellent option to separate the desirable analgesic effects of opioids from their expected dose-limiting side effects to improve postoperative analgesia. Therefore, physicians must better...
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The Effect of Intravenous Injection of Nalbuphine Hydrochloride on CO2 Response Curve in Normal Volunteers

Ham BM, Baik HJ, Yum KW

Nalbuphine, a recently introduced agonist-antagonist analgesic is considered to have analgesic potency similar to morphine in common clinical doses and has been reported to possess an ceiling effect on...
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The effect of transdermal scopolamine plus intravenous dexamethasone for the prevention of postoperative nausea and vomiting in patients with epidural PCA after major orthopedic surgery

Lee HK, Lee JH, Chon SS, Ahn EK, Kim JH, Jang YH

BACKGROUND: Postoperative nausea and vomiting (PONV) is common complication of Patient-Controlled Analgesia (PCA) after surgery. The authors sought to determine whether a transdermal scopolamine (TDS) patch in combination with IV...
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