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Expression of major histocompatibility complex antigen in Lewis rat cornea

Tchah H

Fresh rat corneas as well as corneas preserved in several different corneal preservation media were stained with Avidin-Biotin-peroxidase Complex method in order to evaluate major histocompatibility complex (MHC) antigen expression....
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Cytokine regulation of expression of class I MHC antigens

Raval A, Puri N, Rath PC, Saxena RK

  • KMID: 754981
  • Exp Mol Med.
  • 1998 Mar;30(1):1-13.
No abstract available.
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Species specificity of a novel factor which augments the expression of MHC class I antigens on tumor cell lines

Puri N, Raval A, Saxena RK

  • KMID: 2045609
  • Exp Mol Med.
  • 1997 Jun;29(2):129-132.
A novel factor which augments the expression of major histocompatibility complex I (MHC augmenting factor or MHC-AF) antigens on tumor cell lines, has been isolated from the culture supernatants of...
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The effect of growth factor on antigen and viability of corneal endothelial cells

Tchah H

The effect of epidermal growth factor (EGF) on corneal endothelial cell of rabbit, was evaluated. DNA synthesis of cultured corneal endothelial cells after adding EGF to culture medium and major...
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Immunogenetics of the HLA system

Choo SY

The study of the HLA system was primarily initiated to understand the basis for the histocompatibility between recipients and tissue donors. HLA typing methods are being continuously improved and biochemical...
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Reconstitution of class I MHC molecules expressed in E. coli and complexed with single antigenic peptides

Kim J, Kim MY, Chwae YJ, Park JH

The HLA-Cw3 heavy chain has been expressed at high level as insoluble protein aggregates in E. coli. The protein aggregates dissolved in strong denaturant solution were efficiently reconstituted by...
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The use of crossreactive monoclonal antibodies to characterize the immune system of the water buffalo (Bubalus bubalis)

Davis WC, Khalid AM, Hamilton M, Ahn JS, Park YH, Cantor GH

  • KMID: 1103516
  • J Vet Sci.
  • 2001 Aug;2(2):103-109.
One of the major difficulties in studying the mechanisms of host defense in economically important species indigenous to Asia and the Middle East is the lack of monoclonal antibody (mAb)...
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Partial purification and characterization of a novel murine factor that augments the expression of class I MHC antigens on tumor cells

Puri N, Saxena RK

  • KMID: 754994
  • Exp Mol Med.
  • 1998 Jun;30(2):93-99.
A soluble factor which augments the expression of major histocompatibility complex class I (MHC I) antigens on a number of murine tumor cell lines, has been isolated from the culture supernatants of...
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Two Cases of Transfusion-related Acute Lung Injury Triggered by HLA and Anti-HLA Antibody Reaction

Lee JH, Kang ES, Kim DW

Transfusion-related acute lung injury (TRALI) is a serious adverse transfusion reaction that is presented as acute hypoxemia and non-cardiogenic pulmonary edema, which develops during or within 6 hr of transfusion....
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Alterations of HLA class I and class II antigen expressions in borderline, invasive and metastatic ovarian cancers

Lee YS, Kim TE, Kim BK, Park YG, Kim GM, Jee SB, Ryu KS, Kim IK, Kim JW

  • KMID: 1093593
  • Exp Mol Med.
  • 2002 Mar;34(1):18-26.
In an effort to understand whether HLA class I and II plays any role in the process of tumorigenesis and metastasis, we have immunohistochemically examined expression of HLA class I...
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Alterations of HLA class I and II antigen expression in preinvasive, invasive and metastatic cervical cancers

Ryu KS, Lee YS, Kim BK, Park YG, Kim YW, Hur SY, Kim TE, Kim IK, Kim JW

  • KMID: 938877
  • Exp Mol Med.
  • 2001 Sep;33(3):136-144.
HLA expression is altered in a large variety of human cancers. We performed immunohistochemical staining on tissues from normal, preinvasive, invasive and metastatic cervical cancer tissues using anti-HLA class I...
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Down-regulation of MHC Expression in Human Stem Cells by Introduction of hCMV US Genes

Kim D, Kim JY, Lee EM, Song M, Yang JS, Park JH, Lee JS, Ahn C

  • KMID: 2324324
  • J Korean Soc Transplant.
  • 2003 Dec;17(2):113-120.
PURPOSE: Stem cells are considered promising candidates for cell replacement therapy in many devastating diseases. However, it is assumed that stem cells may be rejected on transplantation. Therefore, we introduced...
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Positive Rate of HLA Class I Antibodies in Multiparous Korean Women

Song EY, Kim SM, Kim BC, Han KS, Park MH

  • KMID: 2225940
  • Korean J Clin Pathol.
  • 2000 Apr;20(2):210-214.
BACKGROUND: Anti-HLA antibodies are most frequently induced by transfusion or pregnancy, and these anibodies can be used as antisera for HLA typing. However these antibodies may elicit adverse reactions such...
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MHC Antigen Expressions in Human Embryonic Neural Stem Cells and Adult Breast Epithelial Stem Cells

Lee EM, Kim JY, Kim D, Cho BR, Koh HS, Yang JS, Lee JS, Ahn C

  • KMID: 2324323
  • J Korean Soc Transplant.
  • 2003 Dec;17(2):105-112.
PURPOSE: Due to their unique capacity to self-renew and for multiple differentiation, stem cells are considered potent candidates for cell replacement therapy in many devastating diseases. However, studies on immune...
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Influence of Mismatching in HLA Cross-Reactive Group on the Graft Survival after Unrelated Kidney Transplantation

Jang S, Oh HB, Han DJ, Park SG

  • KMID: 2225984
  • Korean J Clin Pathol.
  • 2000 Dec;20(6):588-592.
BACKGROUND: Kidney transplantation(KT) from unrelated donors has been increasing in Korea in recent years. However, the number of HLA antigen mismatches in unrelated donor KTis larger compare with that in...
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Down-regulation of MHC class I Expression in Porcine Aortic Endothelial Cells by Introduction of hCMV US Genes

Kim D, Koh HS, Kim JY, Yang JS, Park JH, Park CG, Ha J, Kim SJ, Lee JS, Ahn C

  • KMID: 2201745
  • J Korean Soc Transplant.
  • 2004 Dec;18(2):117-124.
PURPOSE: Direct recognition of porcine MHC proteins by human T cells is an impediment to successful xenotransplantation. Therefore, reducing human T cell response initiated by the interaction between TCR/CD8 cell...
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Monophosphoryl lipid A (MPL) upregulates major histocompatibility complex (MHC) class I expression by increasing interferon-gamma (IFN-gamma)

Cho CH, Lee BK, Kwak SM, Kim JD

Tumor immunity is primarily mediated by cells as CD8+ cytotoxic T lymphocytes (CTL) recognize tumor antigen by MHC class I molecules. But most tumors are associated with a...
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In vivo survival of acid-treated platelets in HLA-immunized rabbits

Cho SR, Kim HO, Song KS, Kwon OH, Shin JW, Kim HJ

  • KMID: 2300125
  • Korean J Blood Transfus.
  • 2000 Dec;11(2):105-113.
BACKGROUND: Platelet refractoriness has been reported to occur in 30-70% of multitransfused patients. This can result by either immune or nonimmune mechanisms. The predominant immune cause of platelet refractoriness is...
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Development of the Home-Made Panel Tray for Panel Reactive Antibody Test

Kim SR, Lee SH, Lee JS, Cho HR, Kim KY, Cho YS, Park RJ, Son HC

  • KMID: 2055400
  • J Clin Pathol Qual Control.
  • 1999 Jun;21(1):229-235.
BACKGROUND: The panel reactive antibody (PRA) test is critical for predicting the probability of cadaver transplantation to possible organ recipients. In Korea, only a few institutions are performing the PRA...
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Comparative Evaluation of ELISA and Luminex Panel Reactive Antibody Assays for HLA Alloantibody Screening

Jung S, Oh EJ, Yang CW, Ahn WS, Kim Y, Park YJ, Han K

BACKGROUND: For the detection of HLA antibodies, solid-phase tests using purified HLA antigens are increasingly used. In this study, we analyzed the panel reactive antibody (PRA) test results using ELISA...
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