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Correlation of HBV DNA Level and Viral Breakthrough During Lamivudine Therapy for Chronic Hepatitis B

Park HS, Lee DH, Heo J, Kim GH, Kang DH, Song GA, Cho M

  • KMID: 760644
  • Korean J Hepatol.
  • 2006 Jun;12(2):173-183.
BACKGROUND/AIMS: Lamivudine is an effective therapy in chronic hepatitis B patients, but the emergence of resistant hepatitis B virus (HBV) mutants is a major concern. This study was performed...
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Comparison of Clinical Outcome Between Patients Continuing and Discontinuing Lamivudine Therapy in Acute Exacerbation After Viral breakthrough During Lamivudine Therapy in Chronic Hepatitis B

Eun JR

  • KMID: 760645
  • Korean J Hepatol.
  • 2006 Jun;12(2):184-190.
BACKGROUNDS/AIMS: Continuation of lamivudine therapy is controversial for patients with chronic hepatitis B when viral breakthrough occurs. Moreover, the effect of continuous lamivudine therapy is unknown in patients with...
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Seroepidemiology of HBV infection in South Korea, 1995 through 1999

Jang MK, Lee JY, Lee JH, Kim YB, Kim HY, Lee MS, Park CK, Yoo JY

  • KMID: 759553
  • Korean J Intern Med.
  • 2001 Sep;16(3):153-159.
BACKGROUND: We analyzed serologic data that were obtained from the Korea Association of Health from 1995 to 1999 to estimate the reliable prevalence of HBV in South Korea. METHODS: 603,375,...
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Predictive Factors and Clinical Outcome of Viral Breakthrough during Lamivudine Treatment for Chronic Hepatitis B Infection

Park NH, Shin JW, Park JH, Bang SJ, Kim DH, Joo KR, Kim DH

  • KMID: 1085302
  • Korean J Hepatol.
  • 2003 Dec;9(4):293-303.
BACKGROUND/AIMS: Long-term treatment with lamivudine causes breakthrough, but the clinical course after lamivudine breakthrough is not well known. The aims of this study were to evaluate the clinical course...
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HBV DNA Loss within 24 Weeks Predicts Late Viral Breakthrough in Chronic Hepatitis B

Jeon SR, Jang JY, Jeong SW, Park SH, Lee SH, Kim SG, Cheon YK, Kim YS, Cho YD, Moon JH, Kim HS, Lee JS, Kim BS

BACKGROUND/AIMS: Sustained HBV DNA reduction is necessary for biochemical remission, histological improvement, and prevention of complications. We analyzed the time taken from HBV DNA loss to viral breakthrough after antiviral...
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