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Epidemiology and prevention of hepatitis B virus infection

Kwon SY, Lee CH

Hepatitis B virus (HBV) infection has been a major global cause of morbidity and mortality. The recognition of the problem led to a worldwide effort to reduce transmission of HBV...
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Definition, Diagnosis, and Prevalence of Occult Hepatitis B Virus Infection

Kim YS

Occult HBV infection is characterized by the absence of serum HBsAg with persistence of low level of intrahepatic HBV DNA. Several suggested mechanisms for the origin of occult HBV infection...
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In vivo hepatitis B virus-neutralizing activity of an anti-HBsAg humanized antibody in chimpanzees

Kim SH, Oh HK, Ryu CJ, Park SY, Hong HJ

Previously, we constructed a humanized antibody (HuS10) that binds to the common a antigenic determinant on the S protein of HBV. In this study, we evaluated its HBV-neutralizing activity in...
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Inactive hepatitis B surface antigen carriers and intrafamilial tramsmission: results of a 10-year study

Demirturk , Demirdal T

BACKGROUND/AIMS: The aims of the present study were to determine the outcomes of inactive hepatitis B virus (HBV) surface antigen (HBsAg) carriers over a 10-year study period and to elucidate...
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A Study on Viral Hepatitis Markers and Abnormal Liver Function Test in Adults Living in Northwest Area of Chungnam

Kim SB, Lee WK, Choi H, Kim SM, Noh R, Kang HY, Lee SS, Ra SS, Gong JH, Shin HD

BACKGROUND/AIMS: We studied the prevalence of chronic hepatitis B, C and abnormality on liver function among the population in northwest area of Chungnam. METHODS: We have reviewed 40,112 adults who...
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Association of Polymorphism in MicroRNA 604 with Susceptibility to Persistent Hepatitis B Virus Infection and Development of Hepatocellular Carcinoma

Cheong JY, Shin HD, Cho SW, Kim YJ

MicroRNA polymorphisms may be associated with carcinogenesis or immunopathogenesis of infection. We evaluated whether the mircoRNA-604 (miR-604) polymorphism can affect the persistence of hepatitis B virus (HBV) infection, and the...
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Familial clustering of hepatitis B and C viruses in Korea

Kim YS, Ahn YO, Kim DW

In order to evaluate the familial clustering of hepatitis B virus(HBV) and hepatitis C virus(HCV) infections and to elucidate the possible routes of HCV transmission among Korean adults with chronic...
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Risk Factors of Cryptogenic Hepatocellular Carcinoma in Patients with Low Body Mass Index or without Metabolic Syndrome

Song HY, Lee HK, Lee JS, Kim JY, Yim YH, Song TJ, Bae WK, Kim NH, Kim KA

BACKGROUND/AIMS: Many patients are diagnosed with cryptogenic hepatocellular carcinoma (HCC) without metabolic syndrome (MS). We investigated the risk factors for cryptogenic HCC in patients with a low body mass index...
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High efficacy of adefovir and entecavir combination therapy in patients with nucleoside-refractory hepatitis B

Chae HB, Kim MJ, Seo EG, Choi YH, Lee HS, Han JH, Yoon SM, Park SM, Youn SJ

BACKGROUND/AIMS: Newly developed and potent antiviral agents suffer from the problem of drug resistance. Multidrug resistance is a major impediment in the treatment of patients with chronic hepatitis B (CHB)....
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T cell subsets in chronic hepatitis B and the effect of prednisolone withdrawal and interferon alpha-2b

Im EH, Sung JK, Lee SO, Lee KT, Lee SM, Kim SH, Lee BS, Seo KS, Kim SG, Kim JH, Kim NJ, Lee HY

  • KMID: 759077
  • Korean J Intern Med.
  • 1999 Jan;14(1):1-8.
OBJECTIVES: The evaluations of the pathogenetic roles of cell mediated immunity and of the preventive effect for disease progression with interferon(IFN) treatment in patients with chronic active hepatitis-B(CAH-B)...
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Clinical Outcomes of Delayed Clearance of Serum HBsAg in Patients with Chronic HBV Infection

Nam SW, Jung JJ, Bae SH, Choi JY, Yoon SK, Cho SH, Han JY, Han NI, Yang JM, Lee YS

BACKGROUND: Spontaneous delayed clearance of hepatitis B surface antigen (HBsAg) in patients with chronic HBV infection is a rare event. The aim of this study was to investigate the...
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Change in the serologic markers of hepatitis B after allogenic hematopoietic stem-cell transplantation

Woo SY, Cho SH, Lee SM, Koh MB, Noh CH, Kim CW, Choi JY, Yang JM, Han JY, Lee YS

BACKGROUND/AIMS: This study examined the effects of hepatitis B virus (HBV) infection state and immunologic capability in both the recipients and donors of allogenic hematopoietic stem-cell transplantation (allo-HSCT) on changes...
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Clinical features of acute viral hepatitis B in Korea: a multi-center study

Choi HJ, Ko SY, Choe WH, Seo YS, Kim JH, Byun KS, Kim YS, Kim SU, Baik SK, Cheong JY, Kim TY, Kwon OS, Kim JH, Lee CH, Kwon SY

BACKGROUND/AIMS: The incidence of Hepatitis B has significantly declined since the introduction of an HBV vaccination program. The aim of this study was to investigate recent clinical features of acute...
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