- Interactive Effect of Smoking and NQO1 Haplotypes on Lung Cancer Risk
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Kim JH, Hong YC
- KMID: 2133296
- J Korean Med Sci.
- 2015 Mar;30(3):221-226.
- doi: 10.3346/jkms.2015.30.3.221
The role of genetic polymorphisms of NAD(P)H:quinone oxidoreductase 1 (NQO1), which is known to be related to carcinogen metabolism and oxidative status, was evaluated for lung cancer development. The genotypes... -
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- Association between interleukin 6 promoter variants and chronic hepatitis B progression
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Park BL, Lee HS, Kim YJ, Kim JY, Jung JH, Kim LH, Shin HD
- KMID: 1097254
- Exp Mol Med.
- 2003 Apr;35(2):76-82.
Interleukin 6 (IL6) plays an essential role in the regulation of immune response to chronic disease. In this study, the three known single nucleotide polymorphisms (SNPs) in the IL6 promoter... -
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- The Association of SERPINE2 Gene with COPD in a Chinese Han Population
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Wang A, Yin Y, Chen P, Liu Q, Yu Q, Xiao W
- KMID: 1058815
- Yonsei Med J.
- 2011 Nov;52(6):953-960.
- doi: 10.3349/ymj.2011.52.6.953
PURPOSE: Polymorphisms of several candidate genes have been studied and associated with the development of chronic obstructive pulmonary disease (COPD). One such candidate is the SERPINE2 (Serpin peptidase inhibitor, clade... -
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- Sequence Analysis of cytb Gene in Echinococcus granulosus from Western China
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Zhong X, Wang N, Hu D, Wang J, Liu T, Gu X, Wang S, Peng X, Yang G
- KMID: 1792171
- Korean J Parasitol.
- 2014 Apr;52(2):205-209.
Echinococcus granulosus is the causative agent of cystic echinococcosis with medical and veterinary importance in China. Our main objective was to discuss the genotypes and genetic diversity of E. granulosus... -
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- Genetic association of the EGR2 gene with bipolar disorder in Korea
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Kim SH, Song JY, Joo EJ, Lee KY, Shin SY, Lee YH, Ahn YM, Kim YS
- KMID: 1120130
- Exp Mol Med.
- 2012 Feb;44(2):121-129.
- doi: 10.3858/emm.2012.44.2.007
The early growth response gene 2 (EGR2) is located at chromosome 10q21, one of the susceptibility loci in bipolar disorder (BD). EGR2 is involved in cognitive function, myelination, and signal... -
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- De novo mutations in sporadic deletional Duchenne muscular dystrophy (DMD) cases
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Mukherjee , Chaturvedi LS, Srivastava S, Mittal RD, Mittal B
- KMID: 1097259
- Exp Mol Med.
- 2003 Apr;35(2):113-117.
Dinucleotide repeat polymorphism based genetic analysis is a powerful approach to gain insight into rare genetic events like germline mosaicism and de novo mutations. The loss of heterozygosity of polymorphic... -
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- Association of common promoter polymorphisms of MCP1 with hepatitis B virus clearance
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Park BL, Kim YJ, Cheong HS, Kim LH, Choi YH, Lee HS, Shin HD
- KMID: 1115948
- Exp Mol Med.
- 2006 Dec;38(6):694-702.
Hepatocellular carcinoma (HCC) is one of the most common malignant cancers closely associated with chronic infection by the hepatitis B virus (HBV) or the hepatitis C virus (HCV) throughout the... -
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- Comprehensive Variant Screening of the UGT Gene Family
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Kim JY, Cheong HS, Park BL, Kim LH, Namgoong S, Kim JO, Kim HD, Kim YH, Chung MW, Han SY, Shin HD
- KMID: 1779911
- Yonsei Med J.
- 2014 Jan;55(1):232-239.
- doi: 10.3349/ymj.2014.55.1.232
PURPOSE: UGT1A1, UGT2B7, and UGT2B15 are well-known pharmacogenes that belong to the uridine diphosphate glucuronyltransferase gene family. For personalized drug treatment, it is important to study differences in the frequency... -
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- A Novel Association between Lysyl Oxidase Gene Polymorphism and Intracranial Aneurysm in Koreans
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Hong EP, Jeon JP, Kim SE, Yang JS, Choi HJ, Kang SH, Cho YJ
- KMID: 2418938
- Yonsei Med J.
- 2017 Sep;58(5):1006-1011.
- doi: 10.3349/ymj.2017.58.5.1006
PURPOSE: Lysyl oxidase (LOX) controls the cross-linking and maturation of elastin and collagen fibers. In this study, we investigated the association between LOX gene polymorphisms and intracranial aneurysm (IA) formation... -
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