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Expression of Heat Shock Protein 27 and Apoptosis in Renal Cell Carcinomas

Yoon GS

  • KMID: 1593160
  • Korean J Pathol.
  • 2006 Feb;40(1):39-45.
BACKGROUND: Heat shock protein 27 (HSP27) is induced by heat shock and other pathophysiologic stresses, including neoplastic transformation. We examined the relationship between the HSP27 expression and the clinical and...
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Expression of Heat Shock Protein 27 and Alpha B Crystallin in the Retina and Optic Nerve of the Chick Embryo

Seo JH, Kim JY

Heat shock protein 27 (HSP27) and alpha B crystallin (aBC) belong to the small heat shock protein (sHSP) family and have similar amino acid sequences. However, no study has compared...
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Hsp27 expression in osteoblast by thermal stress

Rim JS, Kim BR, Kwon JJ, Jang HS, Lee ES, Jun SH, Woo HI

  • KMID: 2184410
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2008 Jan;30(1):11-21.
AIM OF THE STUDY: Thermal stress is a central determinant of osseous surgical outcomes. Interestingly, the temperatures measured during endosseous surgeries coincide with the temperatures that elicit the heat shock...
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Expression of Heat Shock Protein 27 in Human Chondrocytes Confers Resistance to Apoptosis

Na HY, Kim YT, Chang JS, Park JH, Kim JH, Yoon KD, Jung YY, Kim WS

  • KMID: 2105816
  • J Korean Orthop Assoc.
  • 2002 Feb;37(1):131-136.
PURPOSE: This study was designed to examine whether human articular chondrocytes express heat shock protein 27 (hsp27) and to evaluate the relation between hsp27 and the apoptosis of chondrocytes. MATERIALS AND...
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Heat Shock Protein Induction By An Infrared Warm Compression Device

Kim TH, Han JS, Kim JC

  • KMID: 2337206
  • J Korean Ophthalmol Soc.
  • 2005 May;46(5):875-882.
PURPOSE: To investigate if the use of the infrared warm compression device often used in clinical settings induced heat shock proteins. METHODS: Subjects were heat-treated with an infrared warm compression...
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The Protective Effect of Induced Heat Shock Protein in Human Corneal Epithelial Cells

Han JS, Park EJ, Kim JC

  • KMID: 2206652
  • J Korean Ophthalmol Soc.
  • 2003 Aug;44(8):1879-1885.
PURPOSE: The purposes of study were to assess the expression patterns of heat shock protein (HSP) after glutamine and glutamine with non- lethal heat shock treatment, to evaluate the protective...
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Silencing of Heat Shock Protein 27 Expression Accelerates Doxazosin-induced Apoptosis in Prostate Cancer Cell Line PC-3

Shin SC, Cho JM, Kang JY, Yoo TK, Cho H

PURPOSE: Heat shock proteins (HSPs) are highly expressed during stress responses and cellular adaptation to environmental changes. One such protein is HSP27, a 27kDa protein that prevents cell death induced...
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Expression of Heat Shock Protein 27 according to Gleason Score and Pathologic Stage of Prostate Cancer

Lee SW, Kim EK, Kim SS, Uh HS, Cha KS, Yoo TK

PURPOSE: Heat shock protein 27 (HSP27) is induced by heat shock and other pathophysiologic stresses. We examined the relationship between HSP27 expression and Gleason score and pathologic stage of prostate...
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The Prognostic Impact of Heat Shock Proteins Expression in Patients with Esophageal Cancer: A Meta-Analysis

Wang XW, Shi XH, Tong YS, Cao XF

PURPOSE: Heat shock proteins (HSPs) are highly conserved molecular chaperones. There are various studies that assess the prognostic value of HSPs in patients with esophageal cancer, but the conclusion remains...
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Hsp27 modulation of implant-associated metal ion cytotoxicity of osteoblastic cells

Yoon JH, Ha DJ, Rim JS, Kwon JJ, Jang HS, Lee ES, Kim DS

  • KMID: 1960530
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2006 Mar;28(2):127-135.
OBJECTIVES: The extent of bone formation that occurs at the interface of metallic implants and bone is determined by the number and activity of osteoblastic cells. Stress proteins may be...
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Hsp27 contributes to estrogen regulation of osteoblast apoptosis

Jang HS, Eune JJ, Rim JS, Kwon JJ, Choi CM

  • KMID: 1961098
  • J Korean Assoc Oral Maxillofac Surg.
  • 2004 Aug;30(4):323-330.
Estrogen may promote osteoblast/osteocyte viability by limiting apoptotic cell death. We hypothesize that hsp27 is an estrogen- regulated protein that can promote osteoblast viability by increasing osteoblast resistance to apoptosis....
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Expression of Heat Shock Protein 27 in Prostate Cancer Cell Lines According to the Extent of Malignancy and Doxazosin Treatment

Lee SW, Lee JW, Chung JH, Jo JK

  • KMID: 2320822
  • World J Mens Health.
  • 2013 Dec;31(3):247-253.
PURPOSE: Heat shock protein 27 (HSP27) is known as the material that plays a role in apoptosis control in tumor and cell protection including the immune response, drug tolerance, and...
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Clinicopathological Significance of p53 and HSP27 in Gastric-cancer Patients

Lee HG, Kwon SJ, Baek SS

  • KMID: 2383606
  • J Korean Gastric Cancer Assoc.
  • 2004 Sep;4(3):169-175.
PURPOSE: The tumor suppressor gene p53 has been shown to be a factor in the carcinogenesis or progression of gastric cancer. The mutant p53 has been reported to cause a...
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In vitro Stability of Heat Shock Protein 27 in Serum and Plasma Under Different Pre-analytical Conditions: Implications for Large-Scale Clinical Studies

Zimmermann M, Traxler D, Simader E, Bekos C, Dieplinger B, Lainscak M, Ankersmit , Mueller T

The effects of storage temperatures, repeated freeze-thaw cycles, or delays in separating plasma or serum from blood samples are largely unknown for heat shock protein 27 (HSP27). We evaluated (1)...
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Expression levels of heat shock protein 27 and cellular FLICE-like inhibitory protein in prostate cancer correlate with Gleason score sum and pathologic stage

Lee SW, Cho JM, Cho HJ, Kang JY, Kim EK, Yoo TK

PURPOSE: Heat shock protein (HSP) 27 protects the cell by controlling apoptosis and immune reactions, and c-FLIP (cellular-FLICE inhibitory protein) inhibits apoptosis by inhibiting caspase-8 activity. We investigated the relationship...
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The Expression of Adipophilin Is Frequently Found in Solid Subtype Adenocarcinoma and Is Associated with Adverse Outcomes in Lung Adenocarcinoma

Shin SA, Na HY, Choe JY, Chung D, Park M, Oh S, Kim JE

BACKGROUND: The up-regulation of the lipogenic pathway has been reported in many types of malignant tumors. However, its pathogenic role or clinical significance is not fully understood. The objective of...
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Novel non-apoptotic cell death: ferroptosis

Woo SM, Kwon TK

Ferroptosis is a newly recognized type of cell death that results from iron-dependent lipid peroxidation and is different from other types of cell death, such as apoptosis, necrosis, and autophagic...
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Current Understanding of HMGB1-mediated Autophagy

Kwak MS, Shin JS

Reactive oxygen species (ROS) is an oxidative stress to which cells respond by activating various defense mechanisms or cell death. Autophagy associated with oxidative stress response is a process to...
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Combined Extracts of Artemisia and Green Tea, Mitigated Alcoholic Gastritis Via Enhanced Heat-shock Protein 27

Kim YS, Jeong M, Han YM, Park JM, Kwon SO, Hong SP, Hahm KB

BACKGROUND/AIMS: Several lines of evidence from epidemiologic and laboratory studies have shown that the consumption of Artemisia or green tea extracts (MPGT) is inversely associated with the risk of alcohol-induced...
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Changes in the Muscarinic Receptors on the Colonic Smooth Muscles of Rats with Spinal Cord Injury

Joo MC, Kim YS, Choi ES, Oh JT, Park HJ, Lee MY

OBJECTIVE: To investigate changes in (1) the colonic response to acetylcholine (Ach), (2) the muscarinic (M) receptors in the colon, and (3) the levels of colonic contraction-related proteins after a...
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