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Increased Growth of Human Leukemic HL-60 Cells by Dimethyl Sulfoxide and Dimethylformamide

Kang IC, Oh HM

  • KMID: 1550777
  • Korean J Immunol.
  • 1999 Sep;21(3):285-289.
A recent study has proposed that dimethyl sulfoxide (DMSO) increases the number of HL-60 cells in high cell density conditions by inhibiting cell density-dependent apoptosis. We observed that dimethylformamide (DMF),...
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The Differentiation of HL-60 Cells Causes to Lose their Ability to Express TNF mRNA

Kim JH, Han SJ, Park CS, Chung IY

  • KMID: 1550795
  • Korean J Immunol.
  • 1999 Mar;21(1):47-53.
It is well known that HL-60 cell, a human promyelocytic line, is differentiated into eosinophil-like cells in the presence of butyric acid, and thus the differentiated HL-60 cells have been...
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Sonication Induces Apoptosis in HL-60 Cells

Choi M, Seo I, Suh SI, Suh MH, Baek WK

To investigate a specific mechanism of apoptosis induced by sonication, we applied 20 kHz ultrasound to leukemia cell line HL-60 with different intensities (0-60 W/cm2) and time durations (0-100 sec)....
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Expression of IAP Genes During TPA-Induced Differentiation of HL-60 Cells

Baek WK, Kwon TK, Park JW, Suh MH

  • KMID: 1615432
  • J Bacteriol Virol.
  • 2003 Mar;33(1):113-118.
HL-60 cells (human promyelocytic leukemia cells) differentiate into the monocyte/macrophage like cells that die spontaneously by apoptosis when treated with 12-O-tetradecanoylphorbol-13-acetate (TPA). It is known that inhibitors of apoptosis proteins...
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Toxoplasmacidal effect of HL-60 cells differentiated by dimethylsulfoxide

Choi WY, Nam HW, Yoo JE

In vitro culture of Toxoplasma gondii in HL-60 cells cnd cell-mediated immunity against Toxoplasma in dimethylsulfoxide(DMSO)-induced HL-60 cells, i.e., differentiation into granulocytes, were pursued. HL-60 cells were treated with various...
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Effects of intracellular pH on apoptosis in HL-60 human leukemia cells

Park HJ

The nature of the endonucleases responsible for DNA fragmentation in apoptosis has not yet been clearly defined. The intracellular acidity has been known to greatly affect apoptosis probably by affecting...
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Anti-tumor activity and mitochondrial stability of disulfiram in HL-60 cells

Disulfiram (DSF) is a member of the dithiocarbamate family that can bind copper. Recent studies have shown that DSF has anti-cancer activities, but the mechanism has not been clarified. Therefore,...
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Expression of antigens during HL-60 cell differentiation

Oh JS, Kang IC, Ryu PY, Shin BA, Lee HC

  • KMID: 1694133
  • J Korean Cancer Assoc.
  • 1991 Sep;23(3):536-543.
No abstract available.
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Immunologic Changes of HL-60 Cells by Differentiation Inducing Agents I : Phenotypic Differentiation of FcgammaR and Mac-1

Kim HS, Kim KH, Kim GH, Seoh JY

  • KMID: 2104407
  • J Korean Pediatr Soc.
  • 1998 Oct;41(10):1342-1350.
PURPOSE: Fc receptors and Mac-1 play an important role in the protective response of granulocytes and monocytes against microbial infection. FcgammaRl, FcgammaRll, FcgammaRlll as well as CD11b/ CD18 have never...
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Chemiluminescence assay for the monitoring of phagocytic activity of HL-60 cells stimulated by retinoic acid

Hong EK, Cho YH, Seo KW, Kim CK, Moon JJ, Lee KY, Kim JB

  • KMID: 1694334
  • J Korean Cancer Assoc.
  • 1993 Jun;25(3):423-428.
No abstract available.
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Functional Differentiation of HL-60 Cells by Dimethylsulfoxide and Phorbol 12-myristate 13-acetate

Kim HS, Kim KH, Kim GH, Seoh JY

  • KMID: 1946339
  • J Korean Pediatr Soc.
  • 1999 Mar;42(3):355-363.
PURPOSE: During hematopoietic differentiation of HL-60 cells by DMSO and PMA, we demonstrated functional changes of HL-60 cells-phagocytic activity, respiratory burst, antibody-dependent cell-mediated cytotoxicity(ADCC) and opsonophagocytic activity. METHODS: HL-60 cells(ATCC...
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The Effects of Zinc Ion on the Adriamycin-Induced Apoptosis of HL-60 Cells

Yi JA, Oh JH, Choi DY

  • KMID: 2278182
  • Korean J Pediatr Hematol Oncol.
  • 1999 Oct;6(2):266-274.
PURPOSE: The widely used chemotherapeutic agents exert their anti-cancer effects by the inducing of apoptosis in sensitive tumor cells. Recently, the protective effect of zinc ion on apoptosis has...
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Fcr Receptor and Mac-1 Expression and Functional Differentiation of HL-60 Cells by All-trans Retinoic Acid

Kim HS, Kim KH, Kim GH, Seoh JY

  • KMID: 2142388
  • J Korean Pediatr Soc.
  • 1999 Apr;42(4):462-471.
PURPOSE: During differentiation of HL-60 cells by all-trans retinoic acid(ATRA), we analyzed the expression of Fcr receptors and Mac-1 by molecules of equivalent soluble fluorochromes(MESF) and functional studies. METHODS: HL-60...
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Interferon-gamma susceptibility of HL-60 cells, mononuclear cells of umbilical ord blood and bone marrow

Cheong HJ, Hong DS, Kim SJ, Cheong JH, Lee JY, Lee NS, Park SK, Won JH, Park HS, Kim SI

No abstract available.
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Bis induces growth inhibition and differentiation of HL-60 cells via up-regulation of p27

Seo YJ, Jeon MH, Lee JH, Lee YJ, Youn HJ, Ko JH, Lee JH

  • KMID: 1116208
  • Exp Mol Med.
  • 2005 Dec;37(6):624-630.
Bis (Bag-3, CAIR), a Bcl-2-interacting protein, promotes the anti-apoptotic activity of Bcl-2 and increased levels of Bis have been observed in several disease models. The involvement of Bcl-2 and some...
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Investigation of Chemotactic Activities in Differentiated HL-60 Cells by a Time-lapse Videomicroscopic Assay

Jung YJ, Woo SY, Ryu KH, Jang MH, Miyasaka M, Seoh JY

BACKGROUND: Chemotaxis is one of the cardinal functions of leukocytes, which enables them to be recruited efficiently to the right place at the right time. Analyzing chemotactic activities is important...
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Active adenosine transporter-mediated adenosine entrance into HL-60 cells leads to the induction of apoptosis through down-regulation of c-Myc

Hong SH, Jeong SY, Ahn SG, Hwang IS, Kim IK

  • KMID: 2052796
  • Exp Mol Med.
  • 1997 Sep;29(3):183-190.
Although adenosine (Ado) is being recently recognized as a potent inducer of apoptosis, molecular mechanism of apoptosis by Ado remains to be elucidated. In this study we observed that c-Myc...
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Gliotoxin induces the Apoptosis in HL-60 Cells

Chung HT, Park RK, Choi YK, Lee SR, Kim YH, Cho KH, Jang YW

  • KMID: 1557245
  • Korean J Immunol.
  • 1998 Dec;20(4):397-403.
Many fungi including Penicillium, Aspergillus, Gliocladium, and Thermoascus produce an epipolythiodioxopiperazine class of fungal metabolite, gliotoxin, which contirbutes the pathogenesis of fungal infection as an immunomodulator and cytotoxic agent. This...
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Screening of protein kinase C-inhibiting herbs using TPA-induced adherence of HL-60 cell

Kim SH, Ahn JS, Kim SY, Yoo KH, Ahn BJ

  • KMID: 1694286
  • J Korean Cancer Assoc.
  • 1993 Feb;25(1):9-14.
No abstract available.
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Apoptosis Induced by Chemotherapeutic Agents in Differentiated HL-60 Human Leukemic Cell Line

Ahn HJ, Im HJ, Sung KW, Lee SB, Lee H

  • KMID: 2072476
  • Korean J Pediatr Hematol Oncol.
  • 1999 Apr;6(1):57-67.
PURPOSE: Chemotherapeutic agents are known to induce cell death in cancer cells by apoptotic mechanisms. This study was to investigate the influence of the differentiation on the apoptotic potential...
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