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Effect of Thiamine Deficiency on Drug Hydroxylation and Level of Cytochrome P-450 in the Rats

Kim BH, Hong YS, Sung NE

Our studies are concerned with cytochrome P-450 content and 2-acetylaminofluorene N-and ring-hydroxylation by thiamine deficient rat liver microsomes. Incubation medium contained 100mM HEPES buffer pH 7.8, 2mM NADPH, 100mM KF,...
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Optimized Methods to Maintain Motility and Viability in Normozoospermic Males

You YA, Mohamed EA, Oh SA, Pang MG

  • KMID: 1986913
  • Korean J Reprod Med.
  • 2009 Mar;36(1):45-53.
OBJECTIVES: To determinate the optimal culture condition to maintain lifespan in human sperm, we evaluated the effect of different temperature on sperm motility and viability up to 5 days in...
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N-acetyl-L-cysteine and cysteine increase intracellular calcium concentration in human neutrophils

Hasan MA, Ahn WG, Song DK

N-acetyl-L-cysteine (NAC) and cysteine have been implicated in a number of human neutrophils' functional responses. However, though Ca²⁺ signaling is one of the key signalings contributing to the functional responses...
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Effectiveness of Follicular Flushing Aspiration for Low or Poor Responders in Controlled Ovarian Hyperstimulation

Joo JK, Kim SC, Son JB, Ko GR, Kim CW, Lee KS

  • KMID: 2329565
  • J Reprod Endocrinol.
  • 2012 Oct;4(2):113-119.
OBJECTIVES: The aim of this study is to evaluate the effectiveness of follicular flushing aspiration during COH-IVF in low or poor responders. METHODS: 21 COH-IVF cycles were studied. The patients who...
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Flow Cytometric Analysis of Endothelial Cell Viability in Arterial Allograft

Lim CY, Hong EK

  • KMID: 1987901
  • Korean J Thorac Cardiovasc Surg.
  • 1997 Jun;30(6):553-558.
Arterial allografts have known advantages over prosthetic vascular conduit for treatment of heart valvular disease, congenital heart disease and aortic disease. Cell viability may play a role in determining the...
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Modulation of Baseline Potassium Channels in Cerebellar Granule Neurons of Sprague-Dawley Rats by Sevoflurane

Shin WJ, Winegar BD

BACKGROUND: Volatile general anesthetics have been widely used to produce reversible unconsciousness and analgesia in clinical practice over the last one hundred years, but the basic mechanism of anesthetic action...
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Interaction of Sodium Selenite on Neurotoxicity Induced by Methylmercuric Chloride

Park JS, Lee HM, Chung Y, Shin DC, Roh JH, Moon YH

  • KMID: 2282585
  • Korean J Prev Med.
  • 1992 Mar;25(1):13-25.
This study was conducted to investigate the mechanism of protective effect by sodium selenite in Methylmercuric chloride neurotoxicity, increasing intracellular Ca2+ concentration of the neuron. Methylmercuric chloride of 3 mg/kg...
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Octyl Gallate Inhibits ATP-induced Intracellular Calcium Increase in PC12 Cells by Inhibiting Multiple Pathways

Guo Y, Hong YJ, Jang HJ, Kim MJ, Rhie DJ, Jo YH, Hahn SJ, Yoon SH

Phenolic compounds affect intracellular free Ca2+ concentration ([Ca2+]i) signaling. The study examined whether the simple phenolic compound octyl gallate affects ATP-induced Ca2+ signaling in PC12 cells using fura-2-based digital Ca2+...
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Alteration of Phospholipase D Activity in the Rat Tissues by Irradiation

Choi MS, Cho YJ, Choi MU

  • KMID: 2196472
  • J Korean Soc Ther Radiol.
  • 1997 Sep;15(3):197-206.
PURPOSE: Phospholipase D (PLD) catalyzes the hydrolysis of phosphatidyl choline to phosphatidic acid (PA) and choline. Recently, PLD has been drawing much attentions and considered to be associated with cancer...
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Transcriptional Regulation of H2B Histone Gene Expression by Nocodazole in HL-60 Cells

Lim K, Hong YG, Lee MS, Son MY, Yun KA, Park JI, Yoon WH, Park SK, Hwang BD

  • KMID: 2175113
  • J Korean Cancer Assoc.
  • 2000 Apr;32(2):407-416.
PURPOSE: Nocodazole, a microtubule disrupting reagent, is known to arrest cells in the M phase, To gain insight on the regulatory mechanism of H2B histone gene expression by nocodazole in HL-60 cell,...
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Nitric Oxide on the MMP-2 expression by human gingival fibroblasts

Shin IS, Yoon SO, Chung HJ, Koh JT

It has been suggested that increased number and activity of phagocytes in periodontitis lesion results in a high degree of reactive oxygen species (ROS) such as superoxide anion, hydrogen peroxide,...
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Transcriptional REpression of Vimentin Gene During All-TTrans Retinoic Acid-Induced Differentiation of HL-60 Cells

Lim K, Kwon DW, Kim SM, Yoon KA, Son MY, Lee MS, Park JI, Yoon WH, Hwang BD

  • KMID: 1944218
  • J Korean Soc Endocrinol.
  • 1998 Dec;13(4):601-611.
BACKGROUND: Vimentin is the major intermediate-size filament in the cytoplasm of cells from mesenchymal origin. The HL-60 cell is a unique human leukemic cell line capable of terminal differentiation with...
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Role of ATF on Transcriptional Regulation of DNA Topoisomerase II a Gene in HL - 60 Arrested to G2 / M and M Phase

Lim K, Son MY, Choi BI, Yun KA, Zheng M, Kang TW, Lee YC, Park JI, Yoon WH, Hwang BD

  • KMID: 2175140
  • J Korean Cancer Assoc.
  • 1999 Dec;31(6):1279-1287.
PURPOSE: To gain insight on transcriptional repression of Topo II a in HL-60 cells arrested to G2/M and M phase, the levels of Topo IIa mRNA and the binding activity...
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ATP-induced Calcium Mobilization and Proliferation in Cervical Cancer Cells

An WS, Le GH

  • KMID: 2261415
  • Korean J Obstet Gynecol.
  • 1999 Jun;42(6):1332-1338.
PURPOSE: Nucleotides such as ATP can act as extracellular effector molecules by interaction with specific cellular receptors. To know the role of nucleotides in cervical cancer cells, we observed the...
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Role of AP-1 Transcriptional Regulation of Vimentin Gene during 12-O-Tetradecanoylphorbol-13-Acetate Differentiation of HL-60 Cells

Lim K, Kim JH, Kweon DW, Kim SM, Lee MS, Yun KA, Son MY, Park JI, Yoon WH, Hwang BD

  • KMID: 2175342
  • J Korean Cancer Assoc.
  • 1998 Oct;30(5):997-1004.
PURPOSE: To gain insight on the role of AP-1 in transcriptional regulation of vimentin gene during differentiation of HL-60 cells by 12-0-tetradecanoylphorbol-13-acetate (TPA), the levels of vimentin mRNA and AP-1...
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