- Generation and characterization of a monoclonal antibody with high species-specificity to Schistosoma japonicum glutathione S-transferase
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Kim JH, Park JH, Ju SK, Lee MK, Kim KL
- KMID: 1570271
- Immune Netw.
- 2001 Dec;1(3):187-195.
- doi: 10.4110/in.2001.1.3.187
No abstract available. -
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- Effect of p-Dimethylaminoazobenzene and 2(3)-tert-Butyl-4-hydroxyanisole on Lipid Pcroxidation, Glutathione-S-transferase, Peroxidase and Reductase in Rat Liver
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Oh SH, Lee MH
- KMID: 934616
- Yonsei Med J.
- 1981 Dec;22(2):95-100.
- doi: 10.3349/ymj.1981.22.2.95
An experiment was conducted in order to investigate the effect of p-dimethylaminoazobenzene (DAB) and 2(3)-tert-butyl-4-hydroxyanisole (BHA) on the lipid peroxidation and peroxide-destroying enzyme system in the rat liver. Dietary supplementation... -
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- Inductoin of Radioresistance by Overexpression of Glutathione S-Transferase K1 (hGSTK1) in MCF-7 Cells
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Kim JC, Shin SO
- KMID: 1613505
- J Korean Soc Ther Radiol Oncol.
- 2001 Dec;19(4):381-388.
PURPOSE: This study was conducted to assess the effects of x-irradiation on the expression of the novel glutathione S-transferase K1 gene. MATERIALS AND METHODS: Human glutathione S-transferase K1 (hGSTK1) DNA... -
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- Ultrastructural localization of 28 kDa glutathione S-transferase in adult Clonorchis sinensis
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Hong SJ, Yu JR, Kang SY
- KMID: 1384729
- Korean J Parasitol.
- 2002 Dec;40(4):173-176.
- doi: 10.3347/kjp.2002.40.4.173
Glutathione S-transferase (28GST) with molecular mass of 28 kDa is an antioxidant enzyme abundant in Clonorchis sinensis. In adult C. sinensis, 28GST was localized in tegumental syncytium, cytons, parenchyma, and... -
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- The Effect of Hyperthermia on p-Glycoprotein Expression, Glutathione Content and Glutathione-related Enzyme Activities in Human Renal Cell Carcinoma Cells
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Heo YC, Lee ES, Park WH
- KMID: 2060764
- Korean J Urol.
- 1999 Feb;40(2):168-174.
PURPOSE: Resistance to anticancer chemotherapeutic drug remains a major obstacle in cancer chemotherapy. Multidrug-resistance(MDR) gene overexpression and detoxification by glutathione are believed to be involved in adriamycin and cisplatin resistance.... -
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- Schizophrenia and Glutathione S-transferase P Gene Polymorphism
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Pae CU, Lee YM, Yang DH, Kim JJ, Yu HS, Lee CU, Lee SJ, Lee C, Paik IH
- KMID: 2340943
- J Korean Neuropsychiatr Assoc.
- 2004 Jan;43(1):23-28.
OBJECTIVES: This study is aimed to test the association between the coding sequence functional polymorphism (I105 V) of glutathione S-transferase P gene (GSTP1) and schizophrenia. METHODS: Two hundred fourteen (214) patients... -
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- Estrogen receptor 1, Glutathione S-transferase P1, Glutathione S-transferase M1, and Glutathione S-transferase T1 Genes with Dysmenorrhea in Korean Female Adolescents
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Woo HY, Kim KH, Lim SW
- KMID: 1096823
- Korean J Lab Med.
- 2010 Feb;30(1):76-83.
- doi: 10.3343/kjlm.2010.30.1.76
BACKGROUND: Dysmenorrhea is the most common gynecologic complaint among adolescent females. We investigated the association between genetic polymorphisms and dysmenorrhea. METHODS: A total of 202 postmenarcheal Korean female adolescents 16-17... -
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- Induction of Anticarcinogenic Enzymes of Waxy Brown Rice Cultured with Phellinus igniarius 26005
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Park KB, Ha HC, Kim SY, Kim HJ, Lee JS
- KMID: 2312385
- Mycobiology.
- 2002 Dec;30(4):213-218.
The induction of NAD(P)H: quinone oxidoreductase (QR), glutathione S-transferase (GST), and glutathione (GSH) levels in hepa1c1c7 cells (murine hepatoma) by waxy brown rice cultured with Phellinus igniarius to induce anticarcinogenic... -
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- Relationship between Glutathione S Transferase M1 Gene Polymorphism and Endometriosis
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Kim JG, Kim SH, Choi YM, Moon SY, Lee JY
- KMID: 2076845
- Korean J Obstet Gynecol.
- 2003 Mar;46(3):581-586.
OBJECTIVE: To investigate the relationship between glutathione S-transferase M1 (GSTM1) gene polymorphism and endometriosis in Korean women. METHODS: The GSTM1 gene polymorphism was analyzed by GSTM1-specific polymerase chain reaction (PCR) and... -
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- Immunohistochemical Study of Pi Class of Glutathione S-Transferase in Psoriasis and Eczematous Dermatitis
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Cho YW, Song KY, Park SC, Ro BI
- KMID: 2361449
- Ann Dermatol.
- 1994 Jul;6(2):136-139.
- doi: 10.5021/ad.1994.6.2.136
BACKGROUND: Glutathione S-transferase(GST) is a family of isoenzymes that play an important role in protecting cells from cytotoxic and carcinogenic agents. Strong activities of GST-Pi in the epithelial tissues was... -
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- The Change of Glutathione Content in the Placenta of Patients with Pregnancy-induced Hypertension
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Han SJ, Kim WS
- KMID: 2075307
- Korean J Obstet Gynecol.
- 1997 Sep;40(9):1871-1880.
Glutathione has a key role in several detoxification reactions and in the protection against injury caused by reactive oxygens. Pregnancy-induced hypertension(PIH) is associated with endothelial cell dysfunction. Such dysfunction could... -
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- Glutathione S-Transferase M1 Polymorphism and Schizophrenia
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Pae CU, Jo JH, Kim YJ, Kim TS, Kim JJ, Lee CU, Lee SJ, Jun TY, Lee C, Paik IH
- KMID: 2017161
- J Korean Neuropsychiatr Assoc.
- 2004 Sep;43(5):519-523.
OBJECTIVES: This study aimed to test the possible association between Glutathione S-Transferase M1 gene (GSTM1) variants and schizophrenia. METHODS: One hundred and eleven inpatients with schizophrenia and 130 healthy controls were... -
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- The Comparison between FSGS and MCNS Using Proteomic Method in Childhood Nephrotic Syndrome; Preliminary Study
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Kim SD, Cho BS
- KMID: 2322102
- J Korean Soc Pediatr Nephrol.
- 2009 Oct;13(2):170-175.
PURPOSE: FSGS do not respond well to any kind of therapy and gradually progress to end-stage renal disease. This study was conducted to investigate the difference of protein expression between... -
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- Glutathione S-Transferase (GST) Gene Deletions in Korean Patients with Acute Myeloid Leukemia or Myelodysplastic Syndrome
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Woo HY, Lee KA, Hong YJ, Park HS, Kim SH
- KMID: 2143318
- Korean J Hematol.
- 2002 Nov;37(4):265-269.
BACKGROUND: There have been many studies on the association between the glutathione S- transferase (GST) genotype and the susceptibility to acute myeloid leukemia (AML)/myelodysplastic syndrome (MDS) and the results are... -
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- GSTM1, GSTT1 and GSTP1 Polymorphisms in the Korean Population
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Cho HJ, Lee SY, Ki CS, Kim JW
- KMID: 2157771
- J Korean Med Sci.
- 2005 Dec;20(6):1089-1092.
- doi: 10.3346/jkms.2005.20.6.1089
The isoenzymes of the glutathione s transferase (GST) family play a vital role in phase II of biotransformation of many substances. Using a multiplex polymerase chain reaction and a direct... -
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- Different Sources of omega Fatty Acids at the Fixed Ratio of p/s Affect Glutathione Dependent Enzymes in Rat Hepatocarcinogenesis
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Lee HJ, Kim HK, Choi H
- KMID: 1618390
- Korean J Nutr.
- 2003 Oct;36(8):785-792.
This study is conducted to determine the effects of dietary source of omega3 fatty acids on preneoplastic foci and the glutathione dependent enzymes in rat hepatocarcinogenesis initiated by diethylnitrosamine (DEN).... -
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- Polymorphisms within Glutathione S-transferase Genes in Childhood Acute Lymphoblastic Leukemia
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Won SC, Han JW, Lyu CJ
- KMID: 2278312
- Korean J Pediatr Hematol Oncol.
- 2004 Oct;11(2):171-178.
PURPOSE: Glutathione S-transferases (GSTs) are polymorphic genes. Absence of enzyme activity due to homozygous or heterozygous deletion of the gene is associated with reduced detoxification of carcinogens and potentially increasing... -
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- Immunohistochemical Expression of Glutathione S-Transferase pai in Hepatocellulae Carcinoma and Cholangiocarcinoma
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Choi SR, Han SY, Son YG, Lee JH, Park HS, Roh MH, Choi HJ, Huh GY
- KMID: 2143755
- Korean J Gastroenterol.
- 1998 Jan;31(1):58-63.
BACKGROUND AND AIMS: It has been known that glutathione S-transferase n (GST-n ) is overexpressed in chemically induced precancerous or cancerous lesions of the hepatocyte in animal models. Unlike most... -
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- Glutathione S-transferase polymorphism of neonatal hyperbilirubinemia in Korean neonates
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Kang CS, Hong SS, Kim JS, Kim ER
- KMID: 2280398
- Korean J Pediatr.
- 2008 Mar;51(3):262-266.
- doi: 10.3345/kjp.2008.51.3.262
PURPOSE: Glutathione S-transferase (GST) is a polymorphic supergene family of detoxification enzymes that are involved in the metabolism of numerous diseases. Several allelic variants of GSTs show impaired enzyme activity... -
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- Cytosolic Glutathione S-Transferase Change after Deoxycholate Exposure in Colon Cancer Cell Lines
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Park DK, Shin JH, Park SG, Cheung SY
- KMID: 1835108
- J Korean Soc Coloproctol.
- 1998 Dec;14(4):701-708.
PURPOSE: Bile acids (especially deoxycholate) was known to be toxic and mutagenic on colon epithelium. They proposed at least four mechanisms for the bile acid toxicity. It is the one... -
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