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Effects of High Glucose on Interleukin-6 Production in Human Mesangial Cells

Ihm CG, Park JK, Kim HJ, Lee TW, Cha DR

Interleukin (IL)-6 is an autocrine growth factor for mesangial cells. It is not known whether high glucose influences IL-6 production in mesangial cells. Angiotensin II (AGII) is involved in the...
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Changes of 5-hydroxytryptamine release by different glucose concentration from hippocampal slices exposed to hypoxia

Kang DW, Ahn YS

We have previously reported that the spontaneous release of [3H]5-hydroxytryptamine(5-HT) was markedly decreased by hypoxic insult in rat hippocampal slices. In the present study, the effect of glucose on 5-HT...
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Effects of exogenous glucose on survival and infectivity of Schistosoma mansoni cercariae

Fried B, Laterra R, Kim YH

The effects of exogenous glucose in artificial spring water (ASW) were studied on the survival and infectivity of Schistosoma mansoni cercariae. The mean percent survival of cercariae maintained in...
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Role of phospholipase D1 in glucose-induced insulin secretion in pancreatic beta cells

Ma WN, Park SY, Han JS

As glucose is known to induce insulin secretion in pancreatic beta cells, this study investigated the role of a phospholipase D (PLD)-related signaling pathway in insulin secretion caused by high...
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Effect of glucose on the expression of c-myc gene in cultured RINm5F cell

Kim SW, Yang IM, Kim JW, Kim YS, Kim KW, Choi YK, Suh KS

The study was designed to examine the effect of glucose on the expression of c-myc gene in cultured RINm5F cells. After monolayer culture was established in RPMI 1640 media supplemented...
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Ginseng Total Saponin Improves Podocyte Hyperpermeability Induced by High Glucose and Advanced Glycosylation Endproducts

Ha TS, Choi JY, Park HY, Lee JS

Early diabetic nephropathy is characterized by glomerular hyperpermeability as a result of impaired glomerular filtration structure caused by hyperglycemia, glycated proteins or irreversible advanced glycosylation endproducts (AGE). To investigate the...
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Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet beta cells

Kalwat MA, Thurmond D

  • KMID: 2154256
  • Exp Mol Med.
  • 2013 Aug;45(8):e37.
The maintenance of whole-body glucose homeostasis is critical for survival, and is controlled by the coordination of multiple organs and endocrine systems. Pancreatic islet beta cells secrete insulin in response...
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The Effects of Glucose on the Expression of MMP and TIMP in Cultured Retinal Pigment Epithelial Cells

Lee D, Kim JS, Cho HK, Lee JH

This study evaluated the effects of glucose in human retinal pigment epithelial (RPE) cells to investigate the cause of diabetic retinal complications. Human RPE cells were cultured in media containing...
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Delayed Response of Amylin Levels after an Oral Glucose Challenge in Children with Prader-Willi Syndrome

Lee HJ, Choe YH, Lee JH, Sohn YB, Kim SJ, Park SW, Son JS, Kim SW, Jin DK

PURPOSE: Amylin secretion is increased parallel to insulin in obese subjects. Despite their marked obesity, a state of relative hypoinsulinemia occurs in children with Prader-Willi syndrome (PWS). Based on the...
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Regulation of Glomerular Endothelial Cell Proteoglycans by Glucose

Ha TS, Duraisamy , Faulkner J, Kasinath B

The presence of heparan sulfate proteoglycan (HSPG) in anionic sites in the lamina rara interna of glomerular basement membrane suggests that the proteoglycan may be deposited by the glomerular endothelial...
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Oxidative Stress-Activated NHE1 Is Involved in High Glucose-Induced Apoptosis in Renal Tubular Epithelial Cells

Wu Y, Zhang M, Liu R, Zhao C

PURPOSE: Diabetic nephropathy (DN) is a prevalent chronic microvascular complication of diabetes mellitus involving disturbances in electrolytes and the acid-base balance caused by a disorder of glucose metabolism. NHE1 is...
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Effects of Additional Pleurodesis with Dextrose and Talc-Dextrose Solution after Video Assisted Thoracoscopic Procedures for Primary Spontaneous Pneumothorax

Chung WJ, Jo WM, Lee SH, Son HS, Kim KT

Recurrence after thoracoscopic surgery for primary spontaneous pneumothorax is a lingering problem, and many intraoperative methods to induce pleural symphysis have been introduced. We analyzed the effects of chemical pleurodesis...
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