- ras Gene Mutations in Malignant Fibrous Histiocytoma
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Yoo J, Lee AW, Kang SJ, Kim BK
- KMID: 2275609
- Korean J Pathol.
- 2001 Jun;35(3):232-237.
BACKGROUND: ras gene mutations have been described in various human malignancies, suggesting that their activation may play a role in oncogenesis. However, there are few reports concerning ras gene alterations... -
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- Patterns of p53 and H-ras Mutations related to Invasiveness and Differentiation of Transitional Cell Carcinoma in Human bladder
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Woo SH, Lee HL, Kim WJ
- KMID: 2290366
- Korean J Urol.
- 1999 Aug;40(8):963-970.
PURPOSE: To characterize the patterns of p53 & H-ras mutations related to invasiveness and differentiation of transitional cell carcinoma in human bladder. MATERIALS AND METHODS: Tissues from 52 patients diagnosed... -
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- Mutation of the N-ras Gene in a Patient Suffering from the Blast Phase of Chronic Myelogenous Leukemia
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Song SH, Roh YW, Ahn YW, Kim YJ, Byoun YS, Choi JY, Hwang DW, Park BB, Choi JH, Kim IS, Kim BK, Lee YY
- KMID: 2252154
- Korean J Hematol.
- 2009 Jun;44(2):100-103.
- doi: 10.5045/kjh.2009.44.2.100
The blast phase in chronic myelogenous leukemia (CML) is associated with mutation of several genes. It is well known that p53 gene mutation plays a key role in the myeloid... -
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- Mutation of ras oncogene in pancreatic tumor
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Song SY, Kim WH, Chung JB, Kang JK, Park IS, Choi HJ, Park YN, Chun MY
- KMID: 1685448
- Korean J Gastroenterol.
- 1992 Aug;24(4):853-860.
No abstract available. -
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- Telomerase Activity and K-ras Gene Mutation in Pancreatic Juice for Diagnosis of Pancreatic Cancer
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Jung HK, Son HY, Lee HC, Kim DY, Yi SY, Moon IH, Myung SJ, Seo DW, Lee SK, Min YI, Kim MH
- KMID: 2038341
- Korean J Gastroenterol.
- 1999 Aug;34(2):245-254.
BACKGROUND/AIMS: The reactivation of telomerase may be concomitant with the cell immortality and mutations of the K-ras gene are common genetic alteration found in pancreatic carcinomas. The purpose of this... -
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- The relationship of the activation of ras oncogene to hepatitis Bviruss gene expression in human hepatocellular carcinoma
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Han CJ, Lee HS, Kim CY
- KMID: 1685412
- Korean J Gastroenterol.
- 1992 Jun;24(3):547-553.
No abstract available. -
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- Ras Gene Mutations and Expression of ERK1 and ERK2 Proteins in Stomach Cancer
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Yoo J, Kang SJ, Kim BK, Kang CS
- KMID: 2073724
- Korean J Pathol.
- 2002 Apr;36(2):77-83.
BACKGROUND: We investigated stomach cancers for ras abnormalities and expression of ERK1 and ERK2 to determine their significance in the tumor development and/or progression and to evaluate their potential... -
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- Activation Of H-Ras Oncogene In Rat Salivary Gland Tumors Induced By Dmba And Irradiation
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Hu KS, Choi JW, Choi SC, Park TW, You DS
- KMID: 1537338
- J Korean Acad Oral Maxillofac Radiol.
- 1998 Feb;28(1):245-259.
Cellular transforming genes have been identified in a number of different tumor cell lines and tumor types. A significant number of these oncogenes belong to the ras gene family. The... -
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- Expression of Ras Oncogene in the Intracpithelial Neoplasia and Carcinoma of the Uterine Cervix
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Park SS, Choi KY, Nam KH, Lee KH
- KMID: 1675691
- Korean J Gynecol Oncol Colposc.
- 1996 Sep;7(3):217-225.
Cellular oncogenes are expressed as an intrinsic part of the transformed or neoplastic phenotype. More than 60 of the known cellular oncogenes play a specific role in normal cellular development... -
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- Detection of ras gene mutations in human cancer by PCR-SSCP
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Kim CM, Park JI, Kang CD, Kim SH, Park YH, Jung SJ, Jung BS
- KMID: 1694335
- J Korean Cancer Assoc.
- 1993 Jun;25(3):429-444.
No abstract available. -
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- A study about the involvement of H-ras oncogene in acromegalic patients
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Lim SK, Kwon YH, Chung YS, Ahn KJ, Lee EJ, Kim KR, Lee HC, Huh KB, Kim TS
- KMID: 1698312
- Korean J Med.
- 1993 Sep;45(3):353-360.
No abstract available. -
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- Point mutation of K-ras oncogenes by paired polymerase chain reaction and gel electrophoresis in human colorectal cancers
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Park WC, Jeon HM, Chang SK, Choo SY
- KMID: 1693618
- J Korean Surg Soc.
- 1993 Jan;44(1):1-10.
No abstract available. -
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- Significance of K-ras mutation, K-ras expression and p53 expression in pancreatic cancer
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Kim YC, Choi KH, Kim HG, Lee ES, Son GS
- KMID: 2244393
- Korean J Hepatobiliary Pancreat Surg.
- 2000 Feb;4(1):111-121.
BACKGROUND: Though K-ras mutation and aberrant p53 have been considered the event of the oncogenesis of pancreatic adenocarcinoma, it is controversial that these have been attributed to difference of survival... -
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- Significance of K-ras Mutation and p53 Protein Expression in Pancreatic Adenocarcinoma
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Kim YC, Choi KH
- KMID: 2145297
- J Korean Surg Soc.
- 2000 Feb;58(2):271-279.
BACKGROUND: Activation of the K-ras oncogene by specific point mutations at codon 12 occurs at a remarkably high frequency in pancreatic adenocarcinomas. Also, inactivation of the p53 suppressor gene function... -
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- Extracellular Matrix, TGF - beta Gene and Ha-ras Oncogene Expression in Type I Neurofibromatosis
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Jung JB, Kwon HJ, Rhu YW, Lee KS, Song JY
- KMID: 2230634
- Korean J Dermatol.
- 1997 Apr;35(2):249-257.
BACKGROUND: Neurofibroma, the hallmark of neurofibromatosis, is a cutaneous or subcutaneous lesion, with a variable clinical presentation. Histologically, neurofibroma consists of proliferation of nerve derived cellular elements, together with an... -
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- K-ras Gene Mutations and Expression of K-ras, p16, Cyclin D1 and p53 in Synchronous Lesions of The Colon Adenoma-Carcinoma Sequences
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Oh HE, Cho SJ, Won NH, Lee D, Kim I, Yeom BW
- KMID: 1725816
- Korean J Pathol.
- 2001 Aug;35(4):291-298.
BACKGROUND: The colorectal adenoma-carcinoma sequence represents a well-known para-digm for the sequential development of cancer driven by the accumulation of genomic defects. Although the colorectal adenoma-carcinoma sequence has been well... -
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- Expression of ras oncogene in cervical carcinoma and its relevance to prognosis
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Lee HP, Kim WJ, Kim JH, Song YS, Kang SB
- KMID: 1687481
- Korean J Gynecol Oncol Colposc.
- 1993 Mar;4(1):32-42.
We studied 42 with normal eervix and 63 wornen with invasive cervical carcinoma to investigate the correlation between the prognostie variables of the cervical cancer(age, clinical stage, tumor size, depth... -
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- Prevalence of Gsa, ras, p53 Mutations and ret/PTC Rearrangement in Differentiated Thyroid Tumors of Korean Population
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Ahn IM, Kim YI, Park HS, Park KY, Hong SJ, Lee EJ, Gong KY
- KMID: 2142205
- J Korean Soc Endocrinol.
- 1998 Jun;13(2):189-197.
BACKGROUND: In thyroid tumor, ras, Gsa, p53 mutation and ret/FfC rearrangement have been reported with variable prevalences in different geographic regions. We studied the prevalences of these mutations and reammgement... -
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- Identification of mutagenic site of c-H-ras oncogene damaged by N-acetoxyacetylaminofluorene(AAAF)
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Oh SH, Kim KH, Lee SE, Yeh BI
- KMID: 1729587
- Yonsei Med J.
- 1991 Sep;32(3):207-214.
- doi: 10.3349/ymj.1991.32.3.207
A molecularly cloned human cellular H-ras (c-H-ras) oncogene(pbc N1 plasmid) was treated with N-acetoxyacetylaminofluorene (AAAF) in vitro and subcloned into E.coli. This was done to identify the mutational changes at... -
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- Analysis of mutations of ras and p53 gene in multiple myeloma
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Kim JH, Kim YI, Kim SY, Yoon HJ, Cho KS
- KMID: 2143158
- Korean J Med.
- 1998 Mar;54(3):363-374.
BACKGROUND: Multiple myeloma is a malignant prolif eration of plasma cells producing monoclonal immunog lobulins. The pathogenesis of this disease is still unkno wn. Karyotypic complexity and stepwise disease progre ssion in multiple myeloma... -
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