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Fusobacterium nucleatum modulates serum binding to Porphyromonas gingivalis biofilm

Choi J, Kim SJ, Kim SJ

No abstract available.
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Prior Immunization with Fusobacterium Nucleatum Interferes with Opsonophagocytosis Function of Sera against Porphyromonas Gingivalis

Choi JI, Borrello M, Cutler CW, Zauderer M

  • KMID: 2321550
  • J Korean Acad Periodontol.
  • 2000 Mar;30(1):105-110.
No abstract available.
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Isolation of Fusobacterium nucleatum from subgingival plaque in Korean

Jang HS, Kim SH, Kim HS, Kook JK, Kim MK, Yoo SY, Kim BO

The purpose of this study was to isolate and characterize the Fusobacterium nucleatum (F. nucleatum) from subgingival plaque in Korean periodontitis patients. The subgingival plaque samples of periodontitis patient were...
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Effect of Weissella cibaria on Fusobacterium nucleatum-induced Interleukin-6 and Interleukin-8 Production in KB Cells

Kang MS, Lim HS, Kim SM, Lee HC, Oh JS

Oral microorganisms, including pathogens together with commensals, interact with oral epithelial cells, which can lead to the activation and expression of a variety of inflammatory mediators in epithelial cells. Fusobacterium...
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A Case of Liver Abscess Due to Fusobacterium nucleatum

Jung SY, Jung HC, Lee CH, Kim NI, Kim SJ, Lee G, Suh JI, Lee CW, Ha GY, Kim HS, Yang CH

  • KMID: 2085023
  • Korean J Gastroenterol.
  • 2002 May;39(5):386-389.
Fusobacterium is a very rare cause of liver abscess. Fusobacteria are anaerobic gram-negative bacilli that are part of normal flora of the oral cavity, the urogenital tract, and the gastrointestinal...
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A Case of Liver Abscess Caused by Fusobacterium nucleatum in a Patient with Recurrent Periodontal Diseases

Kim YH, Yoon HJ, Park CW, Kim JH, Lee MK, Kim KB, Na DJ, Kim JM

Fusobacteria are anaerobic gram-negative, non-spore forming bacilli found in normal flora of the oral cavity, urogenital tract, and gastrointestinal tract. Fusobacterium nucleatum has been seldom reported as a cause of...
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Prior Exposure of Mice to Fusobacterium Nucleatum Modulates Host Response to Porphyromonas Gingivalis

Son HY, Kim SJ, Choi JI

Multiple periodontal pathogens sequentially colonize the subgingival niche during the conversion from gingivitis to destructive periodontal disease. An animal model of sequential immunization with key periodontal pathogens has been developed...
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Mining the Proteome of Fusobacterium nucleatum subsp. nucleatum ATCC 25586 for Potential Therapeutics Discovery: An In Silico Approach

Habib AM, Islam MS, Sohel M, Mazumder M, Sikder MO, Shahik SM

The plethora of genome sequence information of bacteria in recent times has ushered in many novel strategies for antibacterial drug discovery and facilitated medical science to take up the challenge...
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An in vitro model of Fusobacterium nucleatum and Porphyromonas gingivalis in single- and dual-species biofilms

Tavares LJ, Klein MI, Panariello BHD, Dorigatti de Avila E, Pavarina A

PURPOSE: The goal of this study was to develop and validate a standardized in vitro pathogenic biofilm attached onto saliva-coated surfaces. METHODS: Fusobacterium nucleatum (F. nucleatum) and Porphyromonas gingivalis (P. gingivalis)...
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Cellular and Humoral Immune Responses to Sequential Periodontopathic Bacterial Immunization in Animal Model

Jeon SK, Kim SJ, Choi JI

Antigen-specific T cell clones were obtained from mice immunized with Fusobacterium nucleatum ATCC 10953(F. nucleatum) and/or Porphyromonas gingivalis 381(P. gingivalis). 10 Balb/c mice per group were immunized with F. nucleatum...
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Fusobacterium nucleatum GroEL signaling via Toll-like receptor 4 in human microvascular endothelial cells

Lee HR, Choi BK

  • KMID: 1436486
  • Int J Oral Biol.
  • 2012 Sep;37(3):130-136.
The GroEL heat-shock protein from Fusobacterium nucleatum, a periodontopathogen, activates risk factors for atherosclerosis in human microvascular endothelial cells (HMEC-1) and ApoE-/- mice. In this study, we analyzed the signaling...
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Adhesion of Weissella cibaria to the Epithelial Cells and Factors Affecting its Adhesion

Kang MS, Piao MS, Shin BA, Lee HC, Oh JS

We evaluated the ability of lactic acid bacteria, Weissella cibaria, isolated from the oral cavity to adhere to epithelial cells. W. cibaria efficiently adhered to KB cells and HeLa cells....
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Effects of Microbial Communication on The Growth of Periodontopathogens

Lee CK, Baek DH

  • KMID: 1457213
  • Int J Oral Biol.
  • 2010 Dec;35(4):197-202.
Most oral microorganisms exist as biofilms which initiate formation via the attachment of an early colonizer to host proteins on the tooth surface. Fusobacterium nucleatum act as a bridge between...
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Perturbation of host responses by Porphyromonas gingivalis biofilm

Jeon WS, Kim SJ, Choi JI

The present study was performed to evaluate how cellular and humoral immune responses were perturbed by immunization of mixed periodontal bacterial biofilms. Each group of mice was immunizared with 1)...
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Effect of Sub-Minimal Inhibitory Concentration Antibiotics on Morphology of Periodontal Pathogens

Kwon YW, Lee SY

  • KMID: 1737505
  • Int J Oral Biol.
  • 2014 Jun;39(2):115-120.
Minimal inhibitory concentration (MIC) is the lowest concentration of antibiotics that inhibits the visible growth of a microorganism. It has been reported that sub-MIC of antibiotics may result in morphological...
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Effect of Natural Extracts on Oral Care Probiotics Weissella cibaria CMU and Periodontal Pathogens

Yeu JE, Kim HJ, Kang MS

The purpose of this study is to determine if natural extracts could be used as an additive in oral health food made with Weissella cibaria CMU (oraCMU). Natural extracts of...
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Red fluorescence of oral bacteria interacting with Porphyromonas gingivalis

Kim SY, Woo DH, Lee MA, Kim JS, Lee JH, Jeong SH

OBJECTIVES: Dental plaque is composed of 700 bacterial species. It is known that some oral microorganisms produce porphyrin, and thus, they emit red fluorescence when illuminated with blue light at...
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Prognostic Impact of Fusobacterium nucleatum Depends on Combined Tumor Location and Microsatellite Instability Status in Stage II/III Colorectal Cancers Treated with Adjuvant Chemotherapy

Oh HJ, Kim JH, Bae JM, Kim HJ, Cho NY, Kang GH

BACKGROUND: This study aimed to investigate the prognostic impact of intratumoral Fusobacterium nucleatum in colorectal cancer (CRC) treated with adjuvant chemotherapy. METHODS: F. nucleatum DNA was quantitatively measured in a total...
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Antimicrobial effect of cefixime on 6 species of periodotopathogens

Jang HS, Park MG, Kook JK, Kim HS, Kim BO

The aim of this study was to determine the minimal inhibitory concentration(MIC) of cefi- xime, which is a 3rd generation of cefalosporin, against 6 species of putative periodon- topathogens; Fusobacterium...
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A Hyperactive Neutrophil Phenotype in Aggressive Periodontitis

Kim KY, Kim MK, Choi YS, Kim YC, Jo AR, Rhyu IC, Choi Y

  • KMID: 2170776
  • Int J Oral Biol.
  • 2012 Jun;37(2):69-75.
Although neutrophils function in both defense and tissue destruction, their defensive roles have rarely been studied in association with periodontitis. We hypothesized that peripheral neutrophils are pre-activated in vivo in...
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