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Erratum: Interferon-alpha inhibits airway eosinophila and hyperresponsiveness in an animal asthma model

Kikkawa Y, Sugiyama K, Obara K, Hirata H, Fukushima , Toda M, Fukuda T

The title of the page 256 should be corrected.
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Erratum: Measurement of Hymenoptera venom specific IgE by the IMMULITE 3gAllergy in subjects with negative or positive results by ImmunoCAP

Watanabe M, Hirata H, Arima M, Hayashi Y, Chibana K, Yoshida N, Ikeno Y, Fukushima , Komura R, Okazaki K, Sugiyama K, Fukuda T

We would like to report the following errata in Table 4, and request that these items be revised appropriately.
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Cardiac Rehabilitation Increases Exercise Capacity with a Reduction of Oxidative Stress

Fukuda T, Kurano M, Fukumura K, Yasuda T, Iida H, Morita T, Yamamoto Y, Takano N, Komuro I, Nakajima T

BACKGROUND AND OBJECTIVES: Reactive oxygen species (ROS) mediate various signaling pathways that underlie vascular inflammation in atherogenesis and cardiovascular diseases. Cardiac rehabilitation (CR) has a variety of multiple beneficial effects,...
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Anaphylaxis due to caffeine

Sugiyama K, Cho T, Tatewaki M, Onishi S, Yokoyama T, Yoshida N, Fujimatsu , Hirata H, Fukuda T, Fukushima

We report a rare case of anaphylaxis due to caffeine intake. A 27-year-old woman suffered her first episode of anaphylaxis and a positive skin prick test suggested that the anaphylaxis...
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Graphiumins I and J, New Thiodiketopiperazines from the Marine-derived Fungus Graphium sp. OPMF00224

Fukuda T, Nagai K, Kurihara Y, Kanamoto A, Tomoda H

Two new thiodiketopiperazines (TDKPs), designated graphiumins I (1) and J (2), were isolated from the culture broth of the marine-derived fungus Graphium sp. OPMF00224 by solvent extraction, silica gel column...
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Prostaglandin D2 and TH2 Inflammation in the Pathogenesis of Bronchial Asthma

Arima M, Fukuda T

Prostaglandin D2 (PGD2) is a major prostanoid, produced mainly by mast cells, in allergic diseases, including bronchial asthma. PGD2-induced vasodilatation and increased permeability are well-known classical effects that may be...
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Current new challenges in the management of ulcerative colitis

Fukuda T, Naganuma M, Kanai T

Ulcerative colitis (UC) is a chronic inflammatory condition of the gastrointestinal tract. Although the cause of UC is postulated to be multifactorial in nature, including genetic predisposition, epithelial barrier defects,...
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Fecal microbiota transplantation for recurrent Clostridium difficile infection in a patient with ulcerative colitis

Nanki K, Mizuno S, Matsuoka K, Ono K, Sugimoto S, Kiyohara H, Arai M, Nakashima , Takeshita , Saigusa K, Senoh M, Fukuda T, Naganuma M, Kato H, Suda W, Hattori M, Kanai T

Fecal microbiota transplantation (FMT) has been reported as a safe and effective therapy in patients with refractory and recurrent Clostridium difficile infection (CDI). FMT has also been reported as a...
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Olanzapine Attenuates Mechanical Allodynia in a Rat Model of Partial Sciatic Nerve Ligation

Fukuda T, Yamashita , Hisano S, Tanaka M

BACKGROUND: Neuropathic pain is a global clinical problem; nevertheless, nerve injury treatment methods remain limited. Olanzapine has antinociceptive and anti-nueropathic properties; however, its preventive effects have not been assessed in...
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Relationship between sensitivity to dyspnea and fluctuating peak expiratory flow rate in the absence of asthma symptoms

Kamiya K, Sugiyama K, Toda M, Soda S, Ikeda N, Fukushima , Hirata H, Fukushima , Fukuda T

BACKGROUND: Exacerbation of asthma has a negative impact on quality of life and increases the risk of fatal asthma. One of the known risk factors for patients with a history...
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Interferon-alpha inhibits airway eosinophila and hyperresponsiveness in an animal asthma model

Kikkawa Y, Sugiyama K, Obara K, Hirata H, Fukushima , Toda M, Fukuda T

BACKGROUND: Asthma is characterized by a chronic inflammatory process involving high numbers of inflammatory cells and mediators which have multiple inflammatory effects on the airway. Interferon (IFN)-alpha, which is used...
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5-Aminosalicylic acid intolerance is associated with a risk of adverse clinical outcomes and dysbiosis in patients with ulcerative colitis

Mizuno S, Ono K, Mikami Y, Naganuma M, Fukuda T, Minami K, Masaoka T, Terada S, Yoshida T, Saigusa K, Hirahara N, Miyata H, Suda W, Hattori M, Kanai T

Background/Aims: 5-Aminosalicylic acid (ASA) causes intolerance reactions in some patients. This study was performed to examine the prognosis of patients with ulcerative colitis (UC) and 5-ASA intolerance, and to evaluate...
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Allopregnanolone suppresses mechanical allodynia and internalization of neurokinin-1 receptors at the spinal dorsal horn in a rat postoperative pain model

Fujita M, Fukuda T, Sato Y, Takasusuki T, Tanaka M

BACKGROUND: To identify a new strategy for postoperative pain management, we investigated the analgesic effects of allopregnanolone (Allo) in an incisional pain model, and also assessed its effects on the...
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Measurement of Hymenoptera venom specific IgE by the IMMULITE 3gAllergy in subjects with negative or positive results by ImmunoCAP

Watanabe M, Hirata H, Arima M, Hayashi Y, Chibana K, Yoshida N, Ikeno Y, Fukushima , Komura R, Okazaki K, Sugiyama K, Fukuda T

BACKGROUND: Patients may receive negative results from a specific IgE (sIgE) test such as the ImmunoCAP (CAP) despite a documented history of systemic reaction to a Hymenoptera sting. Thus, further...
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¹²³I-Labeled oxLDL Is Widely Distributed Throughout the Whole Body in Mice

Nakano A, Kawashima , Miyake Y, Zeniya T, Yamamoto A, Koshino K, Temma T, Fukuda T, Fujita Y, Kakino A, Kanaya S, Sawamura T, Iida H

PURPOSE: Oxidized low-density lipoprotein (oxLDL) plays a key role in endothelial dysfunction, vascular inflammation, and atherogenesis. The aim of this study was to assess blood clearance and in vivo kinetics...
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