- Cross-Regulation of Innate and Adaptive Immunity: A New Perspective for the Pathogenesis of Inflammatory Bowel Disease
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Oh DY, Koh SJ
- KMID: 2155636
- Gut Liver.
- 2015 May;9(3):263-264.
- doi: 10.5009/gnl15123
No abstract available. -
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- A Family with Axenfeld-Rieger Syndrome: Report of the Clinical and Genetic Findings
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Yang HJ, Lee YK, Joo CK, Moon JI, Mok JW, Park MH
- KMID: 2363769
- Korean J Ophthalmol.
- 2015 Aug;29(4):249-255.
- doi: 10.3341/kjo.2015.29.4.249
PURPOSE: To describe clinical findings in a Korean family with Axenfeld-Rieger syndrome. METHODS: A retrospective review of clinical data about patients with diagnosed Axenfeld-Rieger syndrome. Five affected members of the family... -
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- Increased Expression of Forkhead Box M1 Is Associated with Aggressive Phenotype and Poor Prognosis in Estrogen Receptor-Positive Breast Cancer
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Ahn H, Sim J, Abdul R, Chung MS, Paik SS, Oh YH, Park CK, Jang K
- KMID: 2164446
- J Korean Med Sci.
- 2015 Apr;30(4):390-397.
- doi: 10.3346/jkms.2015.30.4.390
Fox transcription factors play a critical role in the regulation of a variety of biological processes. While FoxM1 behaves like the oncogenic transcription factor, FoxO3a is known as a tumor... -
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- Decreased Expression of Surfactant Protein Genes Is Associated with an Increased Expression of Forkhead Box M1 Gene in the Fetal Lung Tissues of Premature Rabbits
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Hahn WH, Chang JY, Lee KS, Bae CW
- KMID: 1798139
- Yonsei Med J.
- 2013 Nov;54(6):1422-1429.
- doi: 10.3349/ymj.2013.54.6.1422
PURPOSE: Recently, Forkhead box M1 (FoxM1) was reported to be correlated with lung maturation and expression of surfactant proteins (SPs) in mice models. However, no study has been conducted in... -
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- Forkhead Transcription Factor FOXO1 Inhibits Angiogenesis in Gastric Cancer in Relation to SIRT1
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Kim SY, Ko YS, Park J, Choi Y, Park JW, Kim Y, Pyo JS, Yoo YB, Lee JS, Lee BL
- KMID: 2152293
- Cancer Res Treat.
- 2016 Jan;48(1):345-354.
- doi: 10.4143/crt.2014.247
PURPOSE: We previously reported that forkhead transcription factors of the O class 1 (FOXO1) expression in gastric cancer (GC) was associated with angiogenesis-related molecules. However, there is little experimental evidence... -
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- The Role of Hypothalamic FoxO1 on Hyperphagia in Streptozotocin-Induced Diabetic Mice
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Nam-Goong , Kim JG, Kim SJ, Hur SJ, Lee JW, Kim ES, Yun CH, Lee BJ, Kim YI
- KMID: 2231144
- Korean Diabetes J.
- 2009 Oct;33(5):375-381.
- doi: 10.4093/kdj.2009.33.5.375
BACKGROUND: Streptozotocin-induced diabetic animals are characterized by hyperphagia due to deficiencies of insulin and leptin. Forkhead box-containing protein of the O subfamily-1 (FoxO1) regulates energy homeostasis by regulating energy expenditure... -
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- Insulin-dependent suppression of cholesterol 7alpha-hydroxlase is a possible link between glucose and cholesterol metabolisms
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Park WH, Pak YK
- KMID: 1123369
- Exp Mol Med.
- 2011 Oct;43(10):571-579.
- doi: 10.3858/emm.2011.43.10.064
Cholesterol 7alpha-hydroxylase (CYP7A1) regulates the balance between cholesterol supply and metabolism by catalyzing the rate-limiting step of bile acid biosynthesis. The transcriptional activity of CYP7A1 is tightly controlled by various... -
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- Prevalence of Foxp3 Positive T Regulatory Cells is Increased during Progression of Cutaneous Squamous Tumors
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Jang TJ
- KMID: 1782942
- Yonsei Med J.
- 2008 Dec;49(6):942-948.
- doi: 10.3349/ymj.2008.49.6.942
PURPOSE: Forkhead box p3 (Foxp3) positive T regulatory cells (Tregs) have a functionally immunosuppressive property that prevents effector cells from acting against self in autoimmune diseases or a tumor. It... -
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- Expression of TIM-3, Human beta-defensin-2, and FOXP3 and Correlation with Disease Activity in Pediatric Crohn's Disease with Infliximab Therapy
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Kim MJ, Lee WY, Choe YH
- KMID: 2155645
- Gut Liver.
- 2015 May;9(3):370-380.
- doi: 10.5009/gnl13408
BACKGROUND/AIMS: This study investigated the expression of T cell immunoglobulin- and mucin-domain-containing molecule 3 (TIM-3), human beta-defensin (HBD)-2, forkhead box protein 3 (FOXP3), and the frequency of CD4+ CD25+ FOXP3+... -
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- The Regulation of FOXP3 Expression by the Treatment of TGF-beta and the Modification of DNA Methylation in Lung Cancer Cell Lines
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Um SW, Lee SH, Kim H, Kwon OJ, Kim H, Kang JS, Lee WJ
- KMID: 1442850
- Tuberc Respir Dis.
- 2011 Mar;70(3):206-217.
- doi: 10.4046/trd.2011.70.3.206
BACKGROUND: Transcription factor FOXP3 characterizes the thymically derived regulatory T cells. FOXP3 is expressed by cancer cell itself and FOXP3 expression was induced by TGF-beta treatment in pancreatic cancer cell... -
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- Forkhead box O-class 1 and Forkhead box G1 as Prognostic Markers for Bladder Cancer
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Kim TH, Jo SW, Lee YS, Kim YJ, Lee SC, Kim WJ, Yun SJ
- KMID: 1779165
- J Korean Med Sci.
- 2009 Jun;24(3):468-473.
- doi: 10.3346/jkms.2009.24.3.468
Forkhead box O-class 1 (FOXO1) is a key regulator of glucose homeostasis, cell-cycle progression, and apoptosis. Its functions are modulated by forkhead box G1 (FOXG1), which acts as a transcriptional... -
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- Significance of Foxp3 Positive Regulatory T Cell and Tumor Infiltrating T Lymphocyte in Triple Negative Breast Cancer
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Kang H, Cheong H, Cho MS, Koo H, Han WS, Lee KE, Moon BI, Sung SH
- KMID: 2277520
- Korean J Pathol.
- 2011 Feb;45(1):53-61.
BACKGROUND: Triple negative breast cancer (TNBC) is defined as a lack of the expression of estrogen receptor, progesterone receptor and human epidermal growth factor receptor 2 in breast cancer. Many... -
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- In vitro effects of meloxicam on the number, Foxp3 expression, production of selected cytokines, and apoptosis of bovine CD25+CD4+ and CD25-CD4+ cells
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Maslanka T, Jaroszewski JJ
- KMID: 1705513
- J Vet Sci.
- 2013 Jun;14(2):125-134.
- doi: 10.4142/jvs.2013.14.2.125
The purpose of this study was to evaluate the effect of meloxicam (MEL) on selected immune parameters of bovine CD25highCD4+, CD25lowCD4+, and CD25-CD4+ cells. Peripheral blood mononuclear cells (PBMCs) collected... -
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- Subpopulations of Regulatory T Cells in Rheumatoid Arthritis, Systemic Lupus Erythematosus, and Behcet's Disease
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Kim JR, Chae JN, Kim SH, Ha JS
- KMID: 1782132
- J Korean Med Sci.
- 2012 Sep;27(9):1009-1013.
- doi: 10.3346/jkms.2012.27.9.1009
Recently, subpopulations of regulatory T (Treg) cells, resting Treg (rTreg) and activated Treg (aTreg), have been discovered. The authors investigated the relationship between the change of Treg, aTreg and rTreg... -
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- A Novel De Novo Pathogenic Variant in FOXF1 in a Newborn with Alveolar Capillary Dysplasia with Misalignment of Pulmonary Veins
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Ma Y, Jang MA, Yoo HS, Ahn SY, Sung SI, Chang YS, Ki CS, Park WS
- KMID: 2419131
- Yonsei Med J.
- 2017 May;58(3):672-675.
- doi: 10.3349/ymj.2017.58.3.672
Alveolar capillary dysplasia with misalignment of pulmonary veins (ACD/MPV) is an autosomal dominant, fatal developmental disorder of the lungs, with a mortality rate of about 100%. ACD/MPV is caused by... -
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- Tempol Attenuates Renal Fibrosis in Mice with Unilateral Ureteral Obstruction: The Role of PI3K-Akt-FoxO3a Signaling
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Yoon HE, Kim SJ, Kim SJ, Chung S, Shin SJ
- KMID: 1789980
- J Korean Med Sci.
- 2014 Feb;29(2):230-237.
- doi: 10.3346/jkms.2014.29.2.230
This study investigated whether tempol, an anti-oxidant, protects against renal injury by modulating phosphatidylinositol 3-kinase (PI3K)-Akt-Forkhead homeobox O (FoxO) signaling. Mice received unilateral ureteral obstruction (UUO) surgery with or without... -
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- Resveratrol inhibits foam cell formation via NADPH oxidase 1-mediated reactive oxygen species and monocyte chemotactic protein-1
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Park DW, Baek K, Kim JR, Lee JJ, Ryu SH, Chin BR, Baek SH
- KMID: 1123464
- Exp Mol Med.
- 2009 Mar;41(3):171-179.
- doi: 10.3858/emm.2009.41.3.020
Resveratrol is a polyphenolic compound in red wine that has anti-oxidant and cardioprotective effects in animal models. Reactive oxygen species (ROS) and monocyte chemotactic protein-1 (MCP-1) play key roles in... -
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- The Role of Foxo3 in Leydig Cells
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Choi YS, Song JE, Kong BS, Hong JW, Novelli S, Lee EJ
- KMID: 2345887
- Yonsei Med J.
- 2015 Nov;56(6):1590-1596.
- doi: 10.3349/ymj.2015.56.6.1590
PURPOSE: Foxo3 in female reproduction has been reported to regulate proliferation of granulose cells that form follicles. There are no reports so far that discuss on the role of Foxo3... -
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- Trichinella spiralis Infection Suppressed Gut Inflammation with CD4+CD25+Foxp3+ T Cell Recruitment
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Cho MK, Park MK, Kang SA, Choi SH, Ahn SC, Yu HS
- KMID: 1792137
- Korean J Parasitol.
- 2012 Dec;50(4):385-390.
In order to know the effect of pre-existing Trichinella spiralis infection on experimentally induced intestinal inflammation and immune responses, we induced colitis in T. spiralis-infected mice and observed the severity... -
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- The Prognostic Significance of the Tumor-Infiltrating FoxP3-Positive Regulatory T Cells in Gastric Carcinoma
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Noh SJ, Park SY, Kim KR, Kim CY, Kwon KS, Park HS, Lee H, Chung MJ, Moon WS, Jang KY
- KMID: 2277617
- Korean J Pathol.
- 2010 Feb;44(1):9-15.
BACKGROUND: Regulatory T cells (Tregs) are known to be key regulators of immune responses in patients with autoimmune disease and infection and also for attenuating antitumor immunity by the host.... -
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