- Cell-matrix adhesions of soft tissue cells around dental implants
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Lee SW, Rhyu IC, Han CH, Lee JB
- KMID: 1906954
- J Korean Acad Prosthodont.
- 2006 Feb;44(1):73-84.
The importance of soft tissue response to implant abutments has become one of the major issues in current implant dentistry. To date, numerous studies have emphasized on maintaining connective tissue... -
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- Effect of Cryotherapy on Focal Adhesion Kinase in Retinal Pigment Epithelial Cells
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Lee JG, Heo JW, Chung H
- KMID: 2207660
- J Korean Ophthalmol Soc.
- 2005 Feb;46(2):360-365.
PURPOSE: In the pathogenesis of proliferative vitreoretinopathy (PVR), retinal pigment epithelial (RPE) cells do not undergo apoptosis after separation from the basement membrane. In order to investigate the mechanism by... -
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- The Expression of beta- & alpha-Catenin and Focal Adhesion Kinase in Invasive Cervical Cancers
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Moon HS, Choi EA, Chung HW, Kim SC
- KMID: 1925515
- Korean J Obstet Gynecol.
- 2002 Aug;45(8):1317-1323.
OBJECTIVE: E-cadherin/catenin adhesion complex is fundamentally involved in epithelial cancer invasion and metastasis. Focal adhesion kinase (FAK) is one of the molecules that may be involved in the regulation of... -
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- Preferential Cytotoxic Effect of Genistein on G361 Melanoma Cells Via Inhibition of the Expression of Focal Adhesion Kinase
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Park SR, Kwak HH, Park BS, Kim GC
- KMID: 1431133
- Int J Oral Biol.
- 2012 Dec;37(4):189-195.
Resistance to the induction of apoptosis is a possible mechanism by which tumor cells can survive anti-neoplastic treatments. Melanoma is notoriously resistant to anti-neoplastic therapy. Previous studies have demonstrated focal... -
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- Syntenin Is Expressed in Human Follicular Dendritic Cells and Involved in the Activation of Focal Adhesion Kinase
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Cho W, Kim H, Lee JH, Hong SH, Choe J
- KMID: 1493614
- Immune Netw.
- 2013 Oct;13(5):199-204.
- doi: 10.4110/in.2013.13.5.199
Syntenin is an adaptor molecule containing 2 PDZ domains which mediate molecular interactions with diverse integral or cytoplasmic proteins. Most of the results on the biological function of syntenin were... -
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- The Interface between Cytoskeletal Aberrations and Mitochondrial Dysfunction in Alzheimer's Disease and Related Disorders
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Kang DE, Roh SE, Woo JA, Liu T, Bu JH, Jung AR, Lim Y
- KMID: 2052818
- Exp Neurobiol.
- 2011 Jun;20(2):67-80.
- doi: 10.5607/en.2011.20.2.67
The major defining pathological hallmarks of Alzheimer's disease (AD) are the accumulations of Abeta in senile plaques and hyperphosphorylated tau in neurofibrillary tangles and neuropil threads. Recent studies indicate that... -
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- Expression of Cortactin and Focal Adhesion Kinase in Colorectal Adenocarcinoma: Correlation with Clinicopathologic Parameters and Their Prognostic Implication
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Kim YN, Choi JE, Bae JS, Jang KY, Chung MJ, Moon WS, Kang MJ, Lee DG, Park HS
- KMID: 2277486
- Korean J Pathol.
- 2012 Oct;46(5):454-462.
BACKGROUND: Cortactin and focal adhesion kinase (FAK) are two important components among actin cross-linking proteins that play a central role in cell migration. METHODS: The aims of this study were to... -
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- The Outcome of Multiple Slit on Plaque with Plication Technique for the Treatment of Peyronie's Disease
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Shin SH, Jeong HG, Park JJ, Chae JY, Kim JW, Oh MM, Park HS, Kim JJ, Moon DG
- KMID: 2162599
- World J Mens Health.
- 2016 Apr;34(1):20-27.
- doi: 10.5534/wjmh.2016.34.1.20
PURPOSE: To evaluate the postoperative outcome of the multiple slit on plaque plication technique for the treatment of Peyronie's disease. MATERIALS AND METHODS: We retrospectively evaluated 22 patients who underwent plaque... -
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- Focal adhesion linker proteins expression of fibroblast related to adhesion in response to different transmucosal abutment surfaces
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Moon YH, Yoon MK, Moon JS, Kang JH, Kim SH, Yang HS, Kim MS
- KMID: 2118175
- J Adv Prosthodont.
- 2013 Aug;5(3):341-350.
- doi: 10.4047/jap.2013.5.3.341
PURPOSE: To evaluate adherence of human gingival fibroblasts (HGFs) to transmucosal abutment of dental implant with different surface conditions with time and to investigate the roles of focal adhesion linker... -
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- PAUF promotes adhesiveness of pancreatic cancer cells by modulating focal adhesion kinase
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Lee Y, Kim SJ, Min HJ, Jo JY, Park EH, Koh SS
- KMID: 1009968
- Exp Mol Med.
- 2011 May;43(5):291-297.
- doi: 10.3858/emm.2011.43.5.030
Pancreatic cancer is a notorious disease with a poor prognosis and low survival rates, which is due to limited advances in understanding of the molecular mechanism and inadequate development of... -
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- The Control of Tumor Cell Invasiveness in Chondrosarcoma Cell Lines by Modifying Focal Adhesion Kinase Expression
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Kim YH, Park HB, Shin KH, Hahn SB, Lee JW
- KMID: 2105890
- J Korean Orthop Assoc.
- 2002 Aug;37(4):552-558.
PURPOSE: We propose that cell attachment and invasion can be regulated by the modulation of FAK expression in chondrosarcoma cell lines. MATERIALS AND METHODS: The C-terminal domain of FAK (FAK-CD) was... -
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- ATP-induced focal adhesion kinase activity is negatively modulated by phospholipase D2 in PC12 cells
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Bae YS, Ryu SH
- KMID: 938879
- Exp Mol Med.
- 2001 Sep;33(3):150-155.
Extracellular ATP has been known to modulate various cellular responses including mitogenesis, secretion and morphogenic activity in neuronal cells. In the ATP-induced morphogenic activity, focal adhesion kinase(s) such as Fak... -
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- CD98 activation increases surface expression and clusteringof beta 1 integrins in MCF-7 cells through FAK/Src- and cytoskeleton-independent mechanisms
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Kim SM, Hahn JH
- KMID: 756327
- Exp Mol Med.
- 2008 Jun;40(3):261-270.
- doi: 10.3858/emm.2008.40.3.261
CD98, a disulfide-linked 125-kDa heterodimeric type II transmembrane glycoprotein, regulates beta 1 integrin- mediated cell adhesion. However, the molecular mechanisms underlying CD98-mediated activation of beta 1 integrin are presently unclear.... -
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- The Effect of Hydrogen Peroxide on the Migration and FAK Activation in Lens Epithelial Cells
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Park YM, Kim JA, Ahn BT, Wee WR, Lee JH, Lee YC, Kim HS, Joo CK
- KMID: 2109218
- J Korean Ophthalmol Soc.
- 2001 Sep;42(9):1336-1343.
PURPOSE: Hydrogen peroxide has been implicated as a causative factor of various cellular dysfunction, cell death, transformation. In addition, oxidative stress has been suggested as a crucial inducer of cataract... -
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- The control of chondroid cell's adhesiveness by modulation of focal adhesion kinase(FAK) expression
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Lee JW, Kim YH, Hahn SB, Shin KH, Park HB
- KMID: 1828540
- J Korean Orthop Res Soc.
- 2001 Oct;4(2):159-166.
PURPOSE: We propose that cell attachment can be regulated by the modulation of FAK expression using an adenovirus vector. MATERIALS AND METHODS: Chondrocytes and chondroid cells were used in cell... -
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- Diagnosis and Treatment of Vitreomacular Traction Syndrome Using Optical Coherence Tomography
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Lee JG, An GJ, Lee EK
- KMID: 2337074
- J Korean Ophthalmol Soc.
- 2003 Feb;44(2):351-356.
PURPOSE: To determine the benefit of optical coherence tomography (OCT) in the diagnosis of vitreomacular traction syndrome and evaluate the vitreoretinal interface before and after vitreous surgery. METHODS: Medical records... -
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- Luteolin attenuates migration and invasion of lung cancer cells via suppressing focal adhesion kinase and non-receptor tyrosine kinase signaling pathway
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Masraksa W, Tanasawet , Hutamekalin P, Wongtawatchai T, Sukketsiri W
- KMID: 2471880
- Nutr Res Pract.
- 2020 Apr;14(2):127-133.
- doi: 10.4162/nrp.2020.14.2.127
BACKGROUND/OBJECTIVES: Non-small cell lung cancer is mostly recognized among other types of lung cancer with a poor prognosis by cause of chemotherapeutic resistance and increased metastasis. Luteolin has been found... -
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- The effect of granulocyte-macrophage-stimulating factor on the gene expression in human trophoblast of early pregnancy
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Lee HY, Kim SS, Ahn CS, Park YJ, Jun JH, Song H, Moon HS, Park EJ, Hong SY, Park WI
- KMID: 1453755
- Korean J Obstet Gynecol.
- 2010 Oct;53(10):905-914.
- doi: 10.5468/kjog.2010.53.10.905
OBJECTIVE: Granulocyte-macrophage colony-stimulating factor (GM-CSF) facilitates mammalian embryonic development and implantation. However, its biological function after implantation is not elucidated. The aim of this study is to assess the changes... -
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- Microarray Data Analysis of Perturbed Pathways in Breast Cancer Tissues
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Kim C, Choi J, Yoon S
- KMID: 2166421
- Genomics Inform.
- 2008 Dec;6(4):210-222.
Due to the polygenic nature of cancer, it is believed that breast cancer is caused by the perturbation of multiple genes and their complex interactions, which contribute to the wide... -
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- Fundus Autofluorescence, Fluorescein Angiography and Spectral Domain Optical Coherence Tomography Findings of Retinal Astrocytic Hamartomas in Tuberous Sclerosis
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Kwon YK, Kang DJ, Lim JC, Kim JH, Park DH, Shin JP
- KMID: 2213859
- J Korean Ophthalmol Soc.
- 2016 Jan;57(1):134-140.
- doi: 10.3341/jkos.2016.57.1.134
PURPOSE: To analyze the structural and morphological characteristics of retinal astrocytic hamartomas in tuberous sclerosis patients using fundus autofluorescence, fluorescein angiography and spectral-domain optical coherence tomography. CASE SUMMARY: Fundus examination, fundus... -
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