- Discrepancy in Genotyping of Apolipoprotein E between Allele-Specific PCR and Fluorescence Resonance Energy Transfer or Sequencing
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Park CH, Lee ST, Ki CS, Kim JW
- KMID: 1781635
- Korean J Lab Med.
- 2010 Jun;30(3):325-328.
- doi: 10.3343/kjlm.2010.30.3.325
The human apolipoprotein E (APOE) gene contains several single-nucleotide polymorphisms (SNPs) that are distributed across the gene. The genotype of the APOE gene has important implications as a risk factor... -
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- The Usefulness of the New ADAMTS-13 Activity Assay using a Fluorescence-quenching Substrate for the Diagnosis of Thrombotic Thrombocytopenic Purpura
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Jang MJ, Oh SY, Chong SY, Kang MS, Oh D
- KMID: 2083460
- Korean J Hematol.
- 2005 Dec;40(4):226-230.
- doi: 10.5045/kjh.2005.40.4.226
BACKGROUND: Ever since medical professionals have recognized the important role of ADAMTS-13 in the pathogenesis of TTP, several methods to diagnosis the activity of ADAMTS-13 in the plasma of TTP... -
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- A Comparative Study of Apolipoprotein E Genotyping: INNO-LiPA ApoE Kit, Allelic Discrimination with LightCycler, and BioCore ApoE Kit
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Kim IS, Kim HJ, Ki CS, Kim JW
- KMID: 2239057
- Korean J Lab Med.
- 2004 Aug;24(4):255-260.
BACKGROUND: Apolipoprotein E (apoE) polymorphism is associated with the risk and the time of onset of Alzheimer's disease and the risk of developing cardiovascular disease. Therefore, much inter-est in apoE... -
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- A Novel, Potent, Small Molecule AKT Inhibitor Exhibits Efficacy against Lung Cancer Cells In Vitro
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Dinavahi S, Prasanna R, Dharmarajan S, Perumal Y, Viswanadha S
- KMID: 2403412
- Cancer Res Treat.
- 2015 Oct;47(4):913-920.
- doi: 10.4143/crt.2014.057
PURPOSE: Anomalies of Akt regulation, including overexpression in lung cancer, impart resistance to conventional chemotherapy and radiation, thereby implicating this kinase as a therapeutic intervention point. A novel scaffold of... -
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- Clinical Significance of von Willebrand Factor-Cleaving Protease (ADAMTS13) Deficiency in Patients with Sepsis-Induced Disseminated Intravascular Coagulation
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Kim YK, Lee J, Lee KA, Kwon HU
- KMID: 2170254
- Infect Chemother.
- 2009 Apr;41(2):78-81.
- doi: 10.3947/ic.2009.41.2.78
BACKGROUND: Deficiency of von Willebrand factor-cleaving protease, a disintegrin-like and metalloprotease with thrombospondin type 1 motif 13 (ADAMTS13), is thought to be responsible for platelet aggregation and microthrombi formation, which... -
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- Frequency of Pro475Ser Polymorphism of ADAMTS13 Gene and Its Association with ADAMTS-13 Activity in the Korean Population
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Jang MJ, Kim NK, Chong SY, Kim HJ, Lee SJ, Kang MS, Oh D
- KMID: 724255
- Yonsei Med J.
- 2008 Jun;49(3):405-408.
- doi: 10.3349/ymj.2008.49.3.405
PURPOSE: The in vitro study suggested that proline to serine polymorphism in codon 475 (C1423T) of the A Disintegrin and Metalloprotease with ThromboSpondin type 1 repeats-13 (ADAMTS-13) gene is related... -
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