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Analysis of Plasma Long-Chain Fatty Acids in Hypertensive Patients

Kim JS, Kwon GY, Kim SK

  • KMID: 2334500
  • J Korean Soc Clin Pharmacol Ther.
  • 2011 Dec;19(2):166-179.
BACKGROUND: Numerous studies have suggested that polyunsaturated fatty acids (PUFAs)-supplemented diets may decrease cardiovascular morbidity and mortality. Especially, omega-3 PUFAs may exert beneficial effects to the treatment and prevention of...
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Nonalcoholic Fatty Liver Disease: Lifestyle Modification

Yoo KD, Jun DW

  • KMID: 2128460
  • Korean J Med.
  • 2014 Apr;86(4):416-424.
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease. The prevalence of NAFLD is growing gradually worldwide with increases in obesity, sedentary lifestyles, and an...
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Dietary intake of fat and fatty acids by 1–5-year-old children in Korea: a cross-sectional study based on data from the sixth Korea National Health and Nutrition Examination Survey

Baek Y, Shim JE, Song S

BACKGROUND/OBJECTIVES: We examined dietary fat intake and the major food sources by young children in Korea. SUBJECTS/METHODS: A total of 1,041 children aged 1–5 years were identified from the 2013–2015 Korea...
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Comparison of Nutrient Intakes Regarding Stages of Change in Dietary Fiber Increasing for College Students in Kyunggi-Do

Chung EJ

  • KMID: 2233463
  • Korean J Community Nutr.
  • 2005 Oct;10(5):592-602.
This study was conducted to compare nutrient intakes regarding stages of change in dietary fiber increasing behavior. Subjects were consisted of healthy 383 college students (250 females and 133 males)...
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Effects of perilla oil on plasma concentrations of cardioprotective (n-3) fatty acids and lipid profiles in mice

Chung KH, Hwang HJ, Shin KO, Jeon WM, Choi KS

  • KMID: 2313677
  • Nutr Res Pract.
  • 2013 Aug;7(4):256-261.
The aim of this study was to examine the effects of perilla oil as well as several vegetable oils, including flaxseed oil, canola oil, and rice bran oil on plasma...
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Chemical composition of nuts and seeds sold in Korea

Chung KH, Shin KO, Hwang HJ, Choi KS

  • KMID: 2391958
  • Nutr Res Pract.
  • 2013 Apr;7(2):82-88.
Eleven types of nuts and seeds were analyzed to determine their energy (326-733 mg), moisture (1.6-18.3 mg), carbohydrate (8.8-70.9 mg), protein (4.9-30.5 mg), lipid (2.5-69.8 mg), and ash (1.2-5.5 mg)...
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Effects of Panicum miliaceum L. extract on adipogenic transcription factors and fatty acid accumulation in 3T3-L1 adipocytes

Park MY, Seo DW, Lee JY, Sung MK, Lee YM, Jang HH, Choi HY, Kim JH, Park DS

  • KMID: 2313517
  • Nutr Res Pract.
  • 2011 Jun;5(3):192-197.
The dietary intake of whole grains is known to reduce the incidence of chronic diseases such as obesity, diabetes, cardiovascular disease, and cancer. To investigate whether there are anti-adipogenic activities...
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The Role of Diet in Non-alcoholic Fatty Liver Disease

Jun DW

Prevalence of non-alcoholic fatty liver disease (NAFLD) is about 20-25% in Korean adults population. Obesity is strongly associated with NAFLD and the prevention of obesity is a major public issue....
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A Comparison of the Dietary Habit and Nutrient Intakes of Korean Farmers according to Different Family Patterns and Farming Types

Rhie SG, Park Y

  • KMID: 2300802
  • Korean J Community Nutr.
  • 1998 Nov;3(5):739-747.
The purpose of this study was to compare the dietary habit and nutrient intakes of Korean farmers according to their different family patterns and farming types. Food and nutrient intakes...
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Evaluation of fish oil-rich in MUFAs for anti-diabetic and anti-inflammation potential in experimental type 2 diabetic rats

Keapai W, Apichai S, Amornlerdpison D, Lailerd N

The advantages of monounsaturated fatty acids (MUFAs) on insulin resistance and type 2 diabetes mellitus (T2DM) have been well established. However, the molecular mechanisms of the anti-diabetic action of MUFAs...
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Associations of Colorectal Cancer Incidence with Nutrient and Food Group Intakes in Korean Adults: A Case-Control Study

Chun YJ, Sohn SK, Song HK, Lee SM, Youn YH, Lee S, Park H

This study aimed to examine the associations between intakes of various nutrients and food groups and colorectal cancer risk in a case-control study among Koreans aged 20 to 80 years....
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Dietary Oleate Has Beneficial Effects on Every Step of Non-Alcoholic Fatty Liver Disease Progression in a Methionine- and Choline-Deficient Diet-Fed Animal Model

Lee JY, Moon JH, Park JS, Lee BW, Kang ES, Ahn CW, Lee HC, Cha BS

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is increasingly recognized as a major cause of liver-related morbidity and mortality. The underlying mechanisms of disease progression remain poorly understood, and primary therapy...
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Fatty Acid Composition of Tissue Cultured Breast Carcinoma and the Effect of Stearoyl-CoA Desaturase 1 Inhibition

Mohammadzadeh F, Mosayebi G, Montazeri , Darabi M, Fayezi S, Shaaker M, Rahmati M, Baradaran , Mehdizadeh A, Darabi M

  • KMID: 2353068
  • J Breast Cancer.
  • 2014 Jun;17(2):136-142.
PURPOSE: Stearoyl-CoA desaturase 1 (SCD1) is a novel therapeutic target in various malignancies, including breast cancer. The present study was designed to investigate the effect of the pharmacologic inhibition of...
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HMG CoA Reductase Inhibitors Inhibit HCV RNA Replication of HCV Genotype 1b but Not 2a

Chang KS, Jo HJ

Replication of hepatitis C virus (HCV) is regulated by statin, one of 3-hydroxy-3-methylglutaryl CoA reducatase (HMG CoA reductase) inhibitors that block mevalonate pathway and cholesterol biosyntheis, which has been used...
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Effects of Fluvastatin on the Pharmacokinetics of Repaglinide: Possible Role of CYP3A4 and P-glycoprotein Inhibition by Fluvastatin

Lee CK, Choi JS, Bang JS

The purpose of this study was to investigate the effects of fluvastatin on the pharmacokinetics of repaglinide in rats. The effect of fluvastatin on P-glycoprotein and CYP3A4 activity was evaluated....
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Dietary carnosic acid suppresses hepatic steatosis formation via regulation of hepatic fatty acid metabolism in high-fat diet-fed mice

Park MY, Mun ST

  • KMID: 2313683
  • Nutr Res Pract.
  • 2013 Aug;7(4):294-301.
In this study, we examined the hepatic anti-steatosis activity of carnosic acid (CA), a phenolic compound of rosemary (Rosmarinus officinalis) leaves, as well as its possible mechanism of action, in...
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Milk Transfer and Toxicokinetics of Valproic Acid in Lactating Cynomolgus Monkeys

Lee JH, Yu WJ, Jeong EJ, Chung MK

  • KMID: 2317816
  • Toxicol Res.
  • 2013 Mar;29(1):53-60.
Studies on milk transfer of drugs in non-human primates (NHPs) are among the crucial components in the assessment of peri- and postnatal toxicity because of the similarity between NHPs and...
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Effect of Atorvastatin and Clopidogrel Co-Administration After Coronary Stenting in Korean Patients With Stable Angina

Kim GB, Kim JK, Park S, Jeong JJ, Yoon HS, Ko SH, Ko JE, Park SJ, Nam SW, Lee JH, Hyon MS

BACKGROUND AND OBJECTIVES: It was reported that atorvastatin co-administered with clopidogrel for 8 months did not affect the anti-platelet potency of clopidogrel in Korean patients with acute coronary syndrome, but...
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Fatal Rhabdomyolysis in a Patient with Liver Cirrhosis after Switching from Simvastatin to Fluvastatin

Baek SD, Jang SJ, Park SE, Ok TJ, Leem J, Lee HS, Park SJ, Kim TH

HMG-CoA reductase inhibitors (statins) are widely used to treat hypercholesterolemia. Among the adverse effects associated with these drugs are statin-associated myopathies, ranging from asymptomatic elevation of serum creatine kinase to...
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