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The utility of ezetimibe therapy in nonalcoholic fatty liver disease

Jun BG, Cheon GJ

No abstract available.
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Effect of ezetimibe and simvastatin combination in Korean hypercholesterolemic patients

Park JH

  • KMID: 2252428
  • Korean J Med.
  • 2005 May;68(5):473-475.
No abstract available.
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Letter: Comparison of the Efficacy of Rosuvastatin Monotherapy 20 mg with Rosuvastatin 5 mg and Ezetimibe 10 mg Combination Therapy on Lipid Parameters in Patients with Type 2 Diabetes Mellitus (Diabetes Metab J 2019;43:582–9)

Sohn TS

No abstract available.
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Statin and Ezetimibe Combination Therapy Decreases Mean Platelet Volume Compared to Statin Monotherapy

Lee JB, Kim GS, Cho HN

No abstract available.
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Response: Comparison of the Efficacy of Rosuvastatin Monotherapy 20 mg with Rosuvastatin 5 mg and Ezetimibe 10 mg Combination Therapy on Lipid Parameters in Patients with Type 2 Diabetes Mellitus (Diabetes Metab J 2019;43:582–9)

Hwang YC

No abstract available.
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Simvastatin/Ezetimibe Therapy for Recalcitrant Alopecia Areata: An Open Prospective Study of 14 Patients

Choi JW, Suh DW, Lew BL, Sim WY

BACKGROUND: Simvastatin belongs to the statin family, whose members have immunomodulatory activities. Ezetimibe have synergetic effects when co-administered with simvastatin. In several case reports, alopecia totalis and alopecia universalis were...
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Pharmacokinetics of fixed-dose combination of rosuvastatin 20 mg and ezetimibe 10 mg compared to concurrent administration of individual tablets in healthy Korean subjects

Hwang I, Park SI, Lee S, Lee B, Yu KS, Jeon JY, Kim MG

This study aimed to compare the pharmacokinetics of fixed-dose combination (FDC) tablet of rosuvastatin 20 mg/ezetimibe 10 mg with that of concurrent administration of individual rosuvastatin 20 mg tablet and...
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Influence of Previous Statin Therapy on Cholesterol-Lowering Effect of Ezetimibe

Choi YH, Kim Y, Hyeon CW, Hyun S, Kwon JE, Won H, Shin SY, Lee WS, Lee KJ, Kim SW, Kim TH, Kim CJ

BACKGROUND AND OBJECTIVES: The inhibition of cholesterol absorption by ezetimibe increases cholesterol synthesis. The effect of inhibition of cholesterol synthesis on cholesterol absorption is controversial. The influence of these interactions...
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Pharmacokinetic drug interaction between atorvastatin and ezetimibe in healthy Korean volunteers

Park J, Kim CO, Jin BH, Yang S, Park MS, Hong T

Atorvastatin and ezetimibe are frequently co-administered to treat patients with dyslipidemia for the purpose of low-density lipoprotein cholesterol control. However, pharmacokinetic (PK) drug interaction between atorvastatin and ezetimibe has not...
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The Glucotoxicity Protecting Effect of Ezetimibe in Pancreatic Beta Cells via Inhibition of CD36

Yoon JS, Moon JS, Kim YW, Won KC, Lee HW

Inhibition of CD36, a fatty acid transporter, has been reported to prevent glucotoxicity and ameliorate high glucose induced beta cell dysfunction. Ezetimibe is a selective cholesterol absorption inhibitor that blocks...
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Effects of Ezetimibe Added to Ongoing Statin Therapy on C-Reactive Protein Levels in Hypercholesterolemic Patients

Oh MS, Min YJ, Kwon JE, Cho EJ, Kim JE, Lee WS, Lee KJ, Kim SW, Kim TH, Kim CJ, Ryu WS

BACKGROUND AND OBJECTIVES: Ezetimibe alone does not decrease C-reactive protein (CRP) levels in hypercholesterolemic patients. However, several reports have suggested that ezetimibe might potentiate the effect of statin not only...
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Pharmacological Strategies beyond Statins: Ezetimibe and PCSK9 Inhibitors

Choi JY, Na JO

Dyslipidemia, highly elevated, low-density lipoprotein (LDL) cholesterol, is a major cardiovascular risk factor. Statins have been proven to effectively reduce the risk of atherosclerotic cardiovascular disease (ASCVD) and are recommended...
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Effects of ezetimibe on lipid profiles and hemostatic markers in end-stage renal disease

Park KS, Yeo YS, Yoo MH, Choi JS, Jang JW, Boo SJ, Yoo DJ, Kim SB

  • KMID: 2258370
  • Korean J Med.
  • 2009 Oct;77(4):461-471.
BACKGROUND/AIMS: Dyslipidemia is one of the major causes of cardiovascular disease in end-stage renal disease (ESRD) patients. Most of them are dyslipidemic despite the use of lipid-lowering agents. Ezetimibe is...
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Lipid-Lowering Therapy Guidelines

Lee SH

The major guidelines for lipid-lowering therapy (LLT) have been revised recently. Although “higher cardiovascular risk-aggressive LLT with greater absolute clinical benefit” is the main idea underlying all guidelines, there are...
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Combination pharmacotherapy in lipid management

Lee SH

Latest guidelines on lipid management recommend statins as the first-line therapy. Because limited evidence is available on cardiovascular outcomes with varying statin-nonstatin combinations, recommendation levels for these regimens have been...
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Comparison of the Efficacy of Rosuvastatin Monotherapy 20 mg with Rosuvastatin 5 mg and Ezetimibe 10 mg Combination Therapy on Lipid Parameters in Patients with Type 2 Diabetes Mellitus

Hwang YC, Jun JE, Jeong IK, Ahn KJ, Chung HY

BACKGROUND: The apolipoprotein B/A1 (apoB/A1) ratio is a stronger predictor of future cardiovascular disease than is the level of conventional lipids. Statin and ezetimibe combination therapy have shown additional cardioprotective...
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The safety and efficacy of ezetimibe and simvastatin combination therapy in Korean patients with primary hypercholesterolemia

Bae JW, Kim HS, Lee SC, Han KH, Jeon ES

  • KMID: 2252431
  • Korean J Med.
  • 2005 May;68(5):487-497.
BACKGROUND: The prevalence of hypercholesterolemia in Korea is growing. In spite of the wide use of HMG-CoA reductase inhibitors (statins), some patients don't reach optimal cholesterol reduction and suffer hepatotoxicity...
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Ezetimibe decreased nonalcoholic fatty liver disease activity score but not hepatic steatosis

Lee HY, Jun DW, Kim HJ, Oh H, Saeed WK, Ahn H, Cheung RC, Nguyen MH

BACKGROUND/AIMS: A number of clinical trials reported varying effects of cholesterol lowering agents in nonalcoholic fatty liver disease (NAFLD) patients. We, therefore, assessed the changes in hepatic steatosis and NAFLD...
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Effects of Statins on the Epicardial Fat Thickness in Patients with Coronary Artery Stenosis Underwent Percutaneous Coronary Intervention: Comparison of Atorvastatin with Simvastatin/Ezetimibe

Park JH, Park YS, Kim YJ, Lee IS, Kim JH, Lee JH, Choi SW, Jeong JO, Seong IW

BACKGROUND: Epicardial fat is a visceral thoracic fat and known to be related with presence of dyslipidemia and coronary arterial stenosis. We evaluated the effects and differences of statins on...
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Visual Field Defect after Taking Atorvastatin/Ezetimibe, a Case Study

Kim J, Lee K, Kim J, Lee JM, Kim NY, Lee MS, Ji E

Atorvastatin is one of the most widely prescribed medications for dyslipidemia treatment. In Korea, post combined therapy with ezetimibe, a 73-year-old woman was reported by a community pharmacy to have...
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