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The Effect of Midazolam, Fentanyl and a Small Dose of Etomidate for Prevention of Myoclonus during Induction of Anesthesia with Etomidate

Yang YY, Choi SJ, Kim HJ, Son SC

BACKGROUND: The hypothesis that subcortical disinhibition is the reason for etomidate-induced myoclonus suggest that drugs acting on the subcortical area may reduce myoclonus. To verify the hypothesis, premedication with placebo,...
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The Effect of Midazolam for Reducing Myoclonus after Etomidate

Kwon MS, Kim JH, Baik HJ

BACKGROUND: Etomidate is a rapid acting sedative agent used for the induction of general anesthesia. One of the side effects of etomidate limiting its usage is myoclonus. This...
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The Changes of Plasma Potassium Concentrations during Anesthesia Induction with Etomidate in Patients with Major Burns

Woo CH, Kwak IS, Wie HW, Han TH, Kim KM

BACKGROUND: Etomidate, an anesthetic induction agent, has dose-dependent involuntary myoclonic movement. This prospective, randomized study was conducted to determine the safety of etomidate in patients with major burn injury. METHODS:...
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Induction Dose of Etomidate in the Elderly Patients under General Anesthesia

Moon JH, Chung RK

BACKGROUND: Etomidate is frequently used as an induction agent in the elderly patients. We compared the induction dose of etomidate in the elderly patients. METHODS: Sixty ASA 1-2 patients were...
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Comparisons between Etomidate and Thiopental Sodium as an Induction Agent of General Anesthesia in Elderly Patients

Kim DC, Kim YJ, Han YJ, Song HS

BACKGROUND: This study was designed to determine whether etomidate-based induction can provide better hemodynamics than a standard thiopental sodium-based anesthetic induction in elderly patients. METHODS: Sixty ASA physical...
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The optimal dosage of alfentanil pretreatment for prevention of myoclonus after injection of etomidate

Cho SY, Jeon WJ, Nam YM, Yeom JH, Kim KH

BACKGROUND: Myoclonus is a common problem during induction of general anesthesia with etomidate. We investigated the optimal dosage of alfentanil pretreatment for prevention of myoclonus after injection of etomidate. METHODS: In...
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Effect of Etomidate and Thiopental on Intraocular Pressure associatedwith Induction of Anesthesia and Tracheal Intubation(Facilitated with Succinylcholine)

Kim JW, Kim YH, Lee SW, Choi SJ

BACKGROUND: Good control of intraocular pressure (IOP) during induction and maintenance of anesthesia is essential for the success of intraocular surgery. Etomidate produces a significant and somewhat greater reduction...
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The effects of etomidate on the contraction of pregnant rat uterine smooth muscle

Chung CD, An TH, Jung KT, Lee TH

BACKGROUND: It has been reported that etomidate has the relaxant effects on vascular, tracheal, and non-pregnant uterine smooth muscle in vitro. The purpose of this study was to investigate the...
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Efficacy and Safety of Etomidate Used as a Sedative for Rapid Sequence Intubation in the Emergency Department

Choi SC, Kim GW, Min YG, Yoon SK, Cho JP, Jung YS

  • KMID: 2194039
  • J Korean Soc Emerg Med.
  • 2002 Dec;13(4):503-507.
PURPOSE: The purpose of this study was to estimate the efficacy and the safety of etomidate for rapid sequence intubation (RSI) in the emergency department. METHODS: A retrospective analysis by chart...
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Induction with Intravenous 0.3 mg/kg Etomidate Maintains Venous Capacitance of Normovolemic Rat

Shn JT, Hwang KI, Yang WC, Lee HK, Chung YK

BACKGROUND: Etomidate is short-acting non-barbiturate intravenous anesthetic with minimal cardiovascular depression. As a small change in venous capacitance significantly alters venous return and thus cardiac output, it is important to...
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The effect of fentanyl pretreatment on myoclonus during induction of anesthesia with etomidate in elderly patients

Lee JH, Lee JH, Chin YJ, Lee SI, Chung CJ, Lee SC, Choi SR

BACKGROUND: Etomidate is frequently used as an induction agent in the elderly patients. This study was done to determine whether etomidate-based induction can provide hemodynamic stability and fentanyl decreases the...
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The Effects of Etomidate on Isolated Tracheal Smooth Muscle in Rat

Son YS, Yoon SH, Kim HJ, Lee JU

BACKGROUND: Etomidate is an intravenous anesthetic which has properties of hemodynamic stability, minimal respiratory depression, and cerebral protection. Also, it is a useful induction agent for patients compromised by asthma...
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Effects of Etomidate and Propofol on the Calcium Current in the Rat Myocytes

Kim JU, Choi IC, Ku SW, Kim WT, Han SM, Lee SY, Lee EJ

BACKGROUND: Cardiovascular instability after induction of intravenous anesthetics may be explained partly by direct negative inotropic effects. We studied the effects of etomidate and propofol on the inward calcium currents...
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The Comparison of the Effects of Propofol and Etomidate on Seizure Duration and Hemodynamic Responses during ECT

Lee IH, Kong MH

BACKGROUND: The clinical efficacy of electroconvulsive therapy (ECT) primarily depends on the adequacy of the seizure duration, but the intravenous anesthetics which are commonly used for ECT may possess anticonvulsant...
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The effect of injection rate on etomidate-induced myoclonus

Do SH, Han SH, Park SH, Kim JH, Hwang JY, Son IS, Kim MS

BACKGROUND: Etomidate frequently causes myoclonus. Since the myoclonus is caused by a transient disequilibrium due to etomidate exposure in the CNS, we hypothesized that a slow rate of injection of...
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Comparison of priming versus slow injection for reducing etomidate-induced myoclonus: a randomized controlled study

Mullick P, Talwar V, Aggarwal S, Prakash S, Pawar M

BACKGROUND: Etomidate injection is often associated with myoclonus. Etomidate injection technique influences the incidence of myoclonus. This study was designed to clarify which of the two injection techniques—slow injection or...
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The Effects of Etomidate in the Strips of a Rat Thoracic Aorta

Nan YS, Lee SW, Kim YH, Shin YS, Lee JU

BACKGROUND: The minimal effect of etomidate on cardiovascular function sets it apart from other rapid fast-acting induction agents. Clinically, etomidate has been reported to cause minimal effects on systemic...
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Effects of Etomidate and Midazolam on the Isolated Rabbit Abdominal Aorta and Pulmonary Artery

Yeom JH, Suh JK, Yoo HK

Etomidate and midazolam are newly developed and used in clinical trials. Etmoidate, a carboxylated imidazole derivative, decreases systemic vascular resistance and increases the pulmonary artery pressure in vivo. Midazolam, a...
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Direct Effects of Thiopental, Propofol, Etomidate on Isolated Rat Aorta and Pulmonary artery

Han SJ, Koo BU

The induction agents produce various effects to cardiovascular system. Among these, thio- pental, propofol, and etomidate produce reduction in cardiac output and peripheral vascular resistance. As a result severe systemic...
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Letter to the Editor: Hypotension after Etomidate Use in Sepsis

Andrade FM

No abstract available.
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