- T-cell epitope specificity for Porphyromonas gingivalis heat shock protein in periodontitis
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Lee JY, Lee JY, Choi JI
- KMID: 1999776
- J Korean Acad Periodontol.
- 2003 Dec;33(4):543-553.
- doi: 10.5051/jkape.2003.33.4.543
Due to considerably high degree of sequence homology between bacterial and human heat shock proteins (hsp), it has been widely thought that this protein might be involved in autoimmune disease... -
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- Construction and Characterization of Recombinant Poliovirus that Delivers T-cell epitope
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Cho SP, Lee BY, Chung SI, Min MK
- KMID: 1551975
- J Korean Soc Virol.
- 1998 Jun;28(2):139-146.
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- T Cell Epitope Analysis of Structural Protein of Adenovirus
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Hwang JW, Kim MH, Kim KH
- KMID: 1557251
- Korean J Immunol.
- 1998 Dec;20(4):435-442.
Thelper (Th) cells play a pivotal role in the regulation of immune responses. Since Th epitopes in adenovirus have not yet been defined, in this study, it was attempted to... -
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- Relationship between Poor Immunogenicity of HLA-A2-Restricted Peptide Epitopes and Paucity of Naive CD8+ T-Cell Precursors in HLA-A2-Transgenic Mice
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Choi YS, Lee DH, Shin EC
- KMID: 2150810
- Immune Netw.
- 2014 Aug;14(4):219-225.
- doi: 10.4110/in.2014.14.4.219
We examined the immunogenicity of H-2 class I-restricted and HLA-A2-restricted epitopes through peptide immunization of HLA-A2-transgenic mice that also express mouse H-2 class I molecules. All four of the tested... -
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- Antigenicity of the G2 Glycoprotein in Cell - Mediated Immune Response Against Hantanvirus Infection
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Kim IS, Choi MS, Yi MJ, Han TH
- KMID: 2146922
- J Korean Soc Microbiol.
- 1998 Dec;33(6):619-624.
Hemorrhagic fever with renal syndrom is an acute febrile disease which is caused by Hantanvirus and several other viruses that belong to the genus Hantavirus. Gl and G2 glycoproteins of... -
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- Mutations in the Pre-C and Core Region of Hepatitis B Virus DNA in Chronic HBV Carriers
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Ahn SY, Park JW, Yun SJ, Suh MH, Choi BK
- KMID: 2306316
- Korean J Med.
- 1999 Jan;56(1):1-8.
OBJECTIVES: Causes of diverse clinical sourses of patients with chronic hepatitis B virus(HBV) infection are not fully-known. The host immune response to HBV antigen and the appearance of mutant viruses... -
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- Reverse vaccinology approach for the identification and characterization of outer membrane proteins of Shigella flexneri as potential cellular- and antibody-dependent vaccine candidates
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Leow CY, Kazi A, Hisyam Ismail CMK, Chuah C, Lim BH, Leow CH, Banga Singh KK
- KMID: 2470834
- Clin Exp Vaccine Res.
- 2020 Jan;9(1):15-25.
- doi: 10.7774/cevr.2020.9.1.15
PURPOSE: In the developing world, bacillary dysentery is one of the most common communicable diarrheal infections. There are approximately 169 million cases of shigellosis reported worldwide. The disease is transmitted... -
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- DNA immunization of Mycobacterium tuberculosis resuscitation-promoting factor B elicits polyfunctional CD8+ T cell responses
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Lee J, Kim J, Lee J, Shin SJ, Shin EC
- KMID: 1730629
- Clin Exp Vaccine Res.
- 2014 Jul;3(2):235-243.
- doi: 10.7774/cevr.2014.3.2.235
PURPOSE: T cell-mediated immune responses, and particularly activation of polyfunctional T cells that simultaneously produce multiple cytokines, are necessary for the control of Mycobacterium tuberculosis. In the present study, we... -
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- DNA Vaccines Encoding Toxoplasma gondii Cathepsin C 1 Induce Protection against Toxoplasmosis in Mice
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Han Y, Zhou A, Lu G, Zhao G, Sha W, Wang L, Guo J, Zhou J, Zhou H, Cong H, He S
- KMID: 2395754
- Korean J Parasitol.
- 2017 Oct;55(5):505-512.
- doi: 10.3347/kjp.2017.55.5.505
Toxoplasma gondii cathepsin C proteases (TgCPC1, 2, and 3) are important for the growth and survival of T. gondii. In the present study, B-cell and T-cell epitopes of TgCPC1 were... -
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- Genetic analysis of ORF5 of recent Korean porcine reproductive and respiratory syndrome viruses (PRRSVs) in viremic sera collected from MLV-vaccinating or non-vaccinating farms
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Kim HK, Yang JS, Moon HJ, Park SJ, Luo Y, Lee CS, Song DS, Kang BK, Ann SK, Jun CH, Park BK
- KMID: 1102968
- J Vet Sci.
- 2009 Jun;10(2):121-130.
- doi: 10.4142/jvs.2009.10.2.121
The 23 open reading frame (ORF) 5 sequences of Korean type II porcine reproductive and respiratory syndrome virus (PRRSV) were collected from viremic sera from the (modified live vaccine) MLV-vaccinating... -
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- Subdominant H60 antigen-specific CD8 T-cell response precedes dominant H4 antigen-specific response during the initial phase of allogenic skin graft rejection
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Yoo KI, Jeon JY, Ryu SJ, Nam G, Youn H, Choi EY
- KMID: 2155405
- Exp Mol Med.
- 2015 Feb;47(2):e140.
- doi: 10.1038/emm.2014.107
In allogeneic transplantation, including the B6 anti-BALB.B settings, H60 and H4 are two representative dominant minor histocompatibility antigens that induce strong CD8 T-cell responses. With different distribution patterns, H60 expression... -
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- A novel M2e-multiple antigenic peptide providing heterologous protection in mice
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Wen F, Ma JH, Yu H, Yang FR, Huang M, Zhou YJ, Li ZJ, Wang XH, Li GX, Jiang YF, Tong W, Tong GZ
- KMID: 2363337
- J Vet Sci.
- 2016 Mar;17(1):71-78.
- doi: 10.4142/jvs.2016.17.1.71
Swine influenza viruses (SwIVs) cause considerable morbidity and mortality in domestic pigs, resulting in a significant economic burden. Moreover, pigs have been considered to be a possible mixing vessel in... -
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- Recombinant DNA and Protein Vaccines for Foot-and-mouth Disease Induce Humoral and Cellular Immune Responses in Mice
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Bae JY, Moon SH, Choi JA, Park JS, Hahn BS, Kim KY, Kim B, Song JY, Kwon DH, Lee SC, Kim JB, Yang JS
- KMID: 2150655
- Immune Netw.
- 2009 Dec;9(6):265-273.
- doi: 10.4110/in.2009.9.6.265
BACKGROUND: Foot-and-mouth disease virus (FMDV) is a small single-stranded RNA virus which belongs to the family Picornaviridae, genus Apthovirus. It is a principal cause of FMD which is highly contagious... -
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- Immunoproteasome induction is suppressed in hepatitis C virus-infected cells in a protein kinase R-dependent manner
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Oh IS, Textoris-Taube K, Sung PS, Kang W, Gorny X, Kähne T, Hong SH, Choi YJ, Cammann C, Naumann M, Kim JH, Park SH, Yoo OJ, Kloetzel P, Seifert U, Shin EC
- KMID: 2362294
- Exp Mol Med.
- 2016 Nov;48(11):e270.
- doi: 10.1038/emm.2016.98
By changing the relative abundance of generated antigenic peptides through alterations in the proteolytic activity, interferon (IFN)-γ-induced immunoproteasomes influence the outcome of CD8⺠cytotoxic T lymphocyte responses. In the present... -
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- Role of Citrullinated Fibrinogen Peptides in the Activation of CD4 T Cells from Patients with Rheumatoid Arthritis
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Shin K, Hong S, Choi EH, Lim MK, Shim SC, Ju JH, Lee SH
- KMID: 2150776
- Immune Netw.
- 2013 Aug;13(4):116-122.
- doi: 10.4110/in.2013.13.4.116
This study was conducted to determine whether CD4 T cell responses to citrullinated fibrinogen occur in patients with rheumatoid arthritis (RA), especially in HLA-DR4-positive subjects. Whole peripheral blood mononuclear cells... -
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- Induction of castration by immunization of male dogs with recombinant gonadotropin-releasing hormone (GnRH)-canine distemper virus (CDV) T helper cell epitope p35
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Jung MJ, Moon YC, Cho IH, Yeh JY, Kim SE, Chang WS, Park SY, Song CS, Kim HY, Park KK, McOrist S, Choi IS, Lee JB
- KMID: 1106070
- J Vet Sci.
- 2005 Mar;6(1):21-24.
Immunocastration is a considerable alternative to a surgical castration method especially in male animal species for alleviating unwanted male behaviors and characteristics. Induction of high titer of antibody specific for... -
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