- Neuropeptidomics: Mass Spectrometry-Based Identification and Quantitation of Neuropeptides
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Lee JE
- KMID: 2166535
- Genomics Inform.
- 2016 Mar;14(1):12-19.
- doi: 10.5808/GI.2016.14.1.12
Neuropeptides produced from prohormones by selective action of endopeptidases are vital signaling molecules, playing a critical role in a variety of physiological processes, such as addiction, depression, pain, and circadian... -
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- Partial characterization of a 17 kDa protein of Clonorchis sinensis
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Chung YB, Chung BS, Choi MH, Chai JY, Hong ST
- KMID: 1715242
- Korean J Parasitol.
- 2000 Jun;38(2):95-97.
- doi: 10.3347/kjp.2000.38.2.95
A 17 kDa protein from Clonorchis sinensis adults was purified by a procedure including Sephacryl S-200 HR gel filtration and Q-Sepharose anion exchange chromatography. The protein was proved to be... -
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- A Novel PHEX Gene Mutation in a Patient with Sporadic Hypophosphatemic Rickets
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Kang YE, Hong JH, Kim J, Joung KH, Kim HJ, Ku BJ, Kim KS
- KMID: 2169427
- Endocrinol Metab.
- 2014 Jun;29(2):195-201.
- doi: 10.3803/EnM.2014.29.2.195
Phosphate regulating gene with homologies to endopeptidases on the X-chromosome (PHEX) is a common cause of X-linked hypophosphatemic (XLH) rickets. Diverse PHEX gene mutations have been reported; however, gene mutations... -
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- Activities of different cysteine proteases of Paragonimus westermani in cleaving human IgG
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Chung YB, Yang HJ, Kang SY, Kong Y, Cho SY
- KMID: 1715329
- Korean J Parasitol.
- 1997 Jun;35(2):139-142.
- doi: 10.3347/kjp.1997.35.2.139
Cleaving host immunoglobulins is a well known mechanism of evading host immune reactions exploited by helminth parasites. Secreted cysteine proteases of helminth are a part of enzymes cleaving host IgG.... -
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- Intraocular infusate with hemocoagulase for the control of bleeding during vitreous surgery
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Lee HS, Kim SH, Kim IT
- KMID: 1735035
- Korean J Ophthalmol.
- 1989 Jun;3(1):6-10.
- doi: 10.3341/kjo.1989.3.1.6
The effects of hemocoagulase in injectable form (hemocoagulating enzymatic fraction of South American snake Bothrops jararaca venom provided by Ravizza) on the control of intraocular bleeding during vitreous surgery were... -
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- Asp 280 residue is important in the activity of the Escherichia coli leader peptidase
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Sung MS, Park KS
- KMID: 1029933
- Exp Mol Med.
- 1999 Jun;31(2):64-69.
Leader peptidase is a novel serine protease in Escherichia coli, which catalyzes the cleavage of amino-terminal signal sequences from exported proteins. It is an integral membrane protein containing two transmembrane segments with... -
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- Degradations of human immunoglobulins and hemoglobin by a 60 kDa cysteine proteinase of Trichomonas vaginalis
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Min DY, Hyun KH, Ryu JS, Ahn MH, Cho MH
- KMID: 1715293
- Korean J Parasitol.
- 1998 Dec;36(4):261-268.
- doi: 10.3347/kjp.1998.36.4.261
The present study was undertaken to investigate the role of cysteine proteinase of Trichomonas vaginalis in escaping from host defense mechanism. A cysteine proteinase of T. vaginalis was purified... -
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- Expressional Regulation of Cancer Metastasis Related Gene, MMP-9, by Resveratrol
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Woo JH, Kim YH, Baek WK, Suh SI, Suh MH, Park JW, Kwon TK
- KMID: 1615505
- J Bacteriol Virol.
- 2003 Sep;33(3):235-243.
Proteolytic degradation of the extracellular matrix and tumor metastasis correlate with the expression of endopeptidases known as matrix metalloproteinases (MMPs). Expression of MMPs is regulated by cytokines and signal transduction... -
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- Purification of a 68-kDa cysteine proteinase from crude extract of Pneumocystis carinii
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Choi MH, Chung BS, Chung YB, Yu JR, Cho SR, Hong ST
- KMID: 1720318
- Korean J Parasitol.
- 2000 Sep;38(3):159-166.
- doi: 10.3347/kjp.2000.38.3.159
The present study intended to verify activities of cysteine proteinase of Pneumocystis carinii from rats and to purify the enzyme. In order to exclude the contamination of host-derived enzymes, concentrates... -
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- Relationship between Candida albicans producing proteinase (CAPP) and its environmental pH--comparison with a case of trichophyton mentagrophytes
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Ko IJ, Kim CW, Houh W, Tsuboi R, Matsuda K, Ogawa H
- KMID: 1730654
- J Korean Med Sci.
- 1987 Jun;2(2):97-101.
- doi: 10.3346/jkms.1987.2.2.97
Candida albicans produced a karatinolytic proteinase (KPase) or C. albicans producing proteinase (CAPP), a proposed new term for this enzyme, and Trichophyton mentagrophytes also produced KPase when cultivated in liquid... -
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- Physiological Functionality and Enzyme Activity of Biomass from Pichia anomala Grown on Ginseng-Steaming Effluent
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Kim NM, So SH, Lee SG, Song JE, Seo DS, Lee JS
- KMID: 1487334
- Mycobiology.
- 2008 Sep;36(3):148-151.
- doi: 10.4489/MYCO.2008.36.3.148
A novel biomass was prepared from Pichia anomala KCCM 11473, which grew well in ginseng-steaming effluent (GSE), and its physiological functionalities and enzyme activities were determined. When the strain was... -
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- Comparison of the Effects of Matrix Metalloproteinase Inhibitors on TNF-alpha Release from Activated Microglia and TNF-alpha Converting Enzyme Activity
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Lee EJ, Moon PG, Baek MC, Kim HS
- KMID: 2380318
- Biomol Ther.
- 2014 Sep;22(5):414-419.
- doi: 10.4062/biomolther.2014.099
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that regulate cell-matrix composition and are also involved in processing various bioactive molecules such as cell-surface receptors, chemokines, and cytokines. Our group recently reported... -
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- Differential expression of the 27 kDa cathepsin L-like cysteine protease in developmental stages of Spirometra erinacei
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Kong Y, Yun DH, Cho SY, Sohn WM, Chung YB, Kang SY
- KMID: 1720326
- Korean J Parasitol.
- 2000 Sep;38(3):195-199.
- doi: 10.3347/kjp.2000.38.3.195
The 27 kDa cathepsin L-like cysteine protease of Spirometra erinacei plerocercoid is known to play an important function in tissue penetration, nutrient uptake and immune modulation in human sparganosis. In... -
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- Partial Characterization of Two Cathepsin D Family Aspartic Peptidases of Clonorchis sinensis
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Kang JM, Yoo WG, Lê HG, Thái TL, Hong SJ, Sohn WM, Na BK
- KMID: 2470001
- Korean J Parasitol.
- 2019 Dec;57(6):671-680.
- doi: 10.3347/kjp.2019.57.6.671
Cathepsin D (CatD, EC 3.4.23.5) is a member belonging to the subfamily of aspartic endopeptidases, which are classified into the MEROPS clan AA, family A1. Helminth parasites express a large... -
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- A molecular model of a point mutation (Val297Met) in the serine protease domain of protein C
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Song KS, Park YS, Choi JR, Kim HK, Park Q
- KMID: 755027
- Exp Mol Med.
- 1999 Mar;31(1):47-51.
A heterozygous GTG to ATG (Val297Met) mutation was detected in a patient with inherited protein C deficiency and deep vein thrombosis. Cosegregation of the mutation with protein C deficiency was observed through... -
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- A 54 kDa cysteine protease purified from the crude extract of Neodiplostomum seoulense adult worms
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Choi MH, Choe SC, Lee SH
- KMID: 1715282
- Korean J Parasitol.
- 1999 Mar;37(1):39-46.
- doi: 10.3347/kjp.1999.37.1.39
As a preliminary study for the explanation of pathobiology of Neodiplostomum seoulense infection, a 54 kDa protease was purified from the crude extract of adult worms by sequential chromatographic... -
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- Intestinal Absorption of Fibrinolytic and Proteolytic Lumbrokinase Extracted from Earthworm, Eisenia andrei
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Yan XM, Kim CH, Lee CK, Shin JS, Cho IH, Sohn UD
- KMID: 1457671
- Korean J Physiol Pharmacol.
- 2010 Apr;14(2):71-75.
- doi: 10.4196/kjpp.2010.14.2.71
To investigate the intestinal absorption of a fibrinolytic and proteolytic lumbrokinase extracted from Eisenia andrei, we used rat everted gut sacs and an in situ closed-loop recirculation method. We extracted... -
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- Prognosis of Korean patients with primary biliary cirrhosis
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Song BC
- KMID: 1792588
- Korean J Hepatol.
- 2010 Jun;16(2):109-111.
- doi: 10.3350/kjhep.2010.16.2.109
No abstract available. -
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- The thrombolytic effect of lumbrokinase is not as potent as urokinase in a rabbit cerebral embolism model
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Kim JS, Kang JK, Chang HC, Lee MH, Kim GS, Lee DK, Kim ST, Kim M, Park SY
- KMID: 1421962
- J Korean Med Sci.
- 1993 Apr;8(2):117-120.
- doi: 10.3346/jkms.1993.8.2.117
The purpose of the present study is to determine whether lumbrokinase has an in vivo thrombolytic effect in a rabbit cerebral embolism model. In our previous studies, we found that... -
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- Intactness of zona pellucida does not affect the secretion of a trypsin-like protease from mouse blastocyst
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Hwang SS, Lee EY, Chung YC, Yoon BK, Lee JH, Choi DS
- KMID: 965874
- J Korean Med Sci.
- 2000 Oct;15(5):529-532.
- doi: 10.3346/jkms.2000.15.5.529
Assisted hatching (AH), which is known to improve the hatching potential of mammalian embryos, has been used to increase the pregnancy rate in in vitro fertilization cycles. However, the effect... -
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