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Effect of Low-Dose Enalapril in Patients with Mild to Moderate Hypertension

Bae JH, Kim HJ, Choue CW, Kim KS, Kim MS, Song JS

To evaluate the effect on loe-dose enalapril(ACE inhibitor), we administered a single dose of 10 mg/day enalapril to 22 patients(6 mild hypertension and 16 moderate hypertension) for 12 weeks. The...
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Effect of nicardipine nitroprusside and enalapril on the survival of random pattern skin flaps in rats

Kim HY, Kim BS, Im GY, Lee SY, Cho BH

  • KMID: 1921318
  • J Korean Soc Plast Reconstr Surg.
  • 1991 Nov;18(6):998-1005.
No abstract available.
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Influence of Enalapril on Blood Pressure in Spontaneously Hypertensive Rats

Huh HH, Son UD, Kim CY, Bae JD

We aimed to evaluate the long term trantment of enalapril on the vascular response in the isolated aorta, and in anesthetized or pithed spontaneously hypertensive rats(SHR). In the isolated aorta,...
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Electron Microscopic Study of Enalapril Effect on Left Ventricular Hypertrophy in Spontaneously Hypertensive Rat

Lee BH, Kim JH, Lim HK, Lee CK, Choi IG

Left ventricular hypertrophy is a compensatory response to hemodynamic overload secondary to an increased systemic resistance. This increase, however, is not the only cause of hypertrophy, and there are other...
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Steroid and enalapril therapy: possible cause of toxic epidermal necrolysis

Kim DW, Jung DE, Koo JW

Toxic epidermal necrolysis (TEN) is a rare, acute and life-threatening cutaneous drug reaction. TEN is characterized by the sudden onset of extensive necrosis in the epidermis and frequent mucous membrane...
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Studies on the structural changes of aortic media and its repairing effect by enalapril in spontaneously hypertensive rats

Hong SP, Chung CH

BACKGROUND: It has been known that arteries of hypertensive animals and patients are generally thicker and more rigid than those of normal subjects, resulting from the morphological changes induced by...
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The Effect of Enalapril in the Patients with the Chronic Severe Congestive Heart Failure

Kim JS, Kim MH, Kim JS, Shin JM, Suh YZ, Son JW, Sung MS

ACE inhibitiors have been recently used to treat the chronic congestive heart failure after the use of the antihypertensive agents.The enalapril was added to the chronic congestive heart failure patients...
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Clinical Observation on Antihypertensive Effects of Enalapril

Kwak CH, Chung JH, Lee HW, Chae SC, Jun JE, Park WH

To observe the antihypertensive effects of the angiotensin-converting enzyme inhibitor, enalapril, a daily average dosage of 20mg was administred to 38 patients with essential hypertension for 4 weeks. Changes in...
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Effects of angiotensin converting enzyme inhibition on gene expression of the renin-angiotensin system in rats

Lee YR, Lee MY, Kim WJ, Lee WJ

  • KMID: 2071836
  • Korean J Physiol Pharmacol.
  • 1998 Dec;2(6):771-778.
To investigate interaction of angiotensin converting enzyme (ACE) inhibitor with local tissue renin-angiotensin system (RAS), changes in gene expression of the RAS components in various tissues in response to chronic administration of an...
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A Clinical Study on the Antihypertensive Effects of Enalapril

Jeong MH, Shin SC, Yang SJ, Park SJ, Kim SG, Jo JG, Park JC, Kang JC

A new angiotensin converting enzyme inhibitor, enalapril, was administered in 20 hypertensive patients (7 mild, 6 moderate and 7 severe hypertensives) for 8 weeks or longer in order to see...
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The Effect of Enalapril and Carvedilol on Left Ventricular Dysfunction in Middle Childhood and Adolescent Patients With Muscular Dystrophy

Kwon HW, Kwon BS, Kim GB, Chae JH, Park JD, Bae EJ, Noh CI

BACKGROUND AND OBJECTIVES: In Duchenne and Becker muscular dystrophies, cardiac function deteriorates with time resulting in heart failure which is often fatal. We prospectively evaluated the effect of enalapril and...
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A Randomized, Double-Blind Clinical Trial to Determine the Efficacy of Imidapril vs. Enalapril in Patients with Stage 1 to 2 Essential Hypertension

Choi YJ, Sohn DW, Kim YJ, Lee HJ, Chae IH, Kim HS, Kim CH, Oh BH, Lee MM, Park YB, Choi YS, Lee YW

BACKGROUND: Imidapril is a long-acting angiotensin converting enzyme inhibitor, which has been demons-trated to be effective in reducing blood pressure. The purpose of this study is to compare the antihypertensive...
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Effects of Enalapril on Synthesis of Collagen TypeI, II, III in Incomplete Ureteral Obstruction with Uninephrectomized Rat

Kim JH, Lee YS, Sin MS, Lee JY, Seo SI, Kim JC, Hwang TK

  • KMID: 2292438
  • Korean J Urol.
  • 2001 Jan;42(1):1-9.
PURPOSE: Unilateral ureteral obstruction results in tubulointerstitial fibrosis of the affected kidney which is driven by increased levels of angiotensin II. In this study, we examed the fibrotic changes in...
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The Effect of Enalapril on the Peak Rates of Left Ventricular Wall Movement in Patients with Dilated Cardiomyopathy

Kim CW, Jung YS, Lee KJ, Kwak MH, Kim KM, Kim TH, Kim CJ, Ryu WS, Ryoo UH

  • KMID: 2080506
  • Korean J Med.
  • 1997 May;52(5):617-623.
OBJECTIVE: Angiotensin-converting enzyme inhibitors have been shown to improve survival in patients with congestive heart failure. To evaluate the efficacy of enalapril in patients with dilated cardiomyopathy during concurrent treatment...
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Effect of Enalapril or Lovastatin on Tubulointerstitial Injury Induced by Protein-overload Proteinuria in Rats

Chung SJ, Chung JG, Yang WS, Kim SB, Park SK, Lee SK, Park JS

  • KMID: 1989745
  • Korean J Nephrol.
  • 2001 May;20(3):393-402.
BACKGROUND: Previous studies have demonstrated that enalapril or lovastatin seems to ameliorate the renal injury in several animal models with glomerulonephritis. The aim of this study was to examine whether...
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Effect of angiotensin II inhibition on the epithelial to mesenchymal transition in developing rat kidney

Yim HE, Yoo KH, Bae IS, Hong YS, Lee JW

PURPOSE: To investigate the effects of angiotensin II inhibition on the epithelial to mesenchymal transition (EMT) in the developing kidney, we tested the expression of EMT markers and nestin in...
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A Clinical Study on the Antihypertensive Effect of Enalapril

Son JH, Jung SS, Choi YC, Kim JH, Lim HK, Lee BH, Lee CK

Enalapril, a new angiotensin converting enzyme inhibitor,was administered in 30 hypertensive patients for 12 weeks or longer in order to evaluate the antihypertensive effects and side effects (in some cases...
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Effects of Individual or Combined Treatment with Enalapril and Lovastatin on the Osteopontin Gene Expression in 5/6 Nephrectomized Rats

Kim SB, Park JS, Yang WS, Park SK, Lee SK, Lee JS

  • KMID: 2307278
  • Korean J Nephrol.
  • 1999 Nov;18(6):877-886.
Osteopontin, a secreted, arginine-glycin-asparate (RGD)-containing phosphoprotein is up-regulated in renal cortex in many experimental models of tubu- lointerstitial fibrosis. Osteopontine gene seems to be induced predominantly in chronic and progressive...
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Effect of Enalpril on LVH and LV Performance in Essential Hypertension

Lee DC

BACKGROUND: Left ventricular hypertrophy(LVH) is the independent poor prognostic factor in hypertensives. But, it is uncertain that the reduction of LVH by antihypertensives therapy will improve the prognosis of hypertensive...
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Comparison of Inhibitory Effects between Enalapril and Losartan on Adrenal Catecholamine Secretion

Lim HJ, Koh YY, Lim DY

BACKGROUND: The present study was attempted to compare enalapril, an angiotensin-converting enzyme inhibitor with losartan an angiotensin II (Ang II) receptor blocker in the inhibitory effects on the secretion of...
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