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Omega-3 Index as a Risk Factor for Cardiovascular Disease and Its Application to Korean Population

Park Y

  • KMID: 1461009
  • Korean J Obes.
  • 2010 Mar;19(1):1-8.
Of all known dietary factors, long-chain omega-3 fatty acids (eicosapentaenoic acid and docosahexaenoic acid) may be the most protective against death from cardiovascular disease. Evidence continues to accrue for benefits...
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Effect of Eicosapentaenoic Acid on Endothelial Cell-U937 Cell Adhesion

Chae SC, Kim EJ, Lim HJ, Cheong ER, Cho YK, Jun JE, Park WH

BACKGROUND: Epidemiological studies have shown correlation between low incidence of coronary heart disease and high consumption of fish products. It has been suggested that this may be due to the...
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Serum Fatty Acids in Mother and Umbilical Cord of Full-Term and Preform Delivery

Ahn HS

  • KMID: 2269711
  • Korean J Nutr.
  • 2003 Dec;36(10):1036-1041.
Ecological studies have indicated that the essential fatty acids in maternal and umbilical cord blood samples are associated with gestational length and birth weight. The objectives of this study were...
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Effects of perilla oil on plasma concentrations of cardioprotective (n-3) fatty acids and lipid profiles in mice

Chung KH, Hwang HJ, Shin KO, Jeon WM, Choi KS

  • KMID: 2313677
  • Nutr Res Pract.
  • 2013 Aug;7(4):256-261.
The aim of this study was to examine the effects of perilla oil as well as several vegetable oils, including flaxseed oil, canola oil, and rice bran oil on plasma...
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The Effects of Korean DASH Diet Education Program on Oxidative Stress, Antioxidant Capacity, and Serum Homocysteine Level among Elderly Korean Women

Choi SH, Choi-Kwon , Kwak CS, Lee H

PURPOSE: The purpose of this study was to investigate the effects of the Korean Dietary Approaches to Stop Hypertension (DASH) education program on oxidative stress, antioxidant capacity, and serum homocysteine...
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Effect of Eicosapentaenoic Acid Supplementation on Paraoxonase 2 Gene Expression in Patients with Type 2 Diabetes Mellitus: a Randomized Double-blind Clinical Trial

Golzari MH, Javanbakht MH, Ghaedi E, Mohammadi , Djalali M

Type 2 diabetes mellitus (T2DM) is recognized as one of the most prevalent metabolic diseases, and it is mostly associated with oxidative stress, atherosclerosis and dyslipidemia. Paraoxonase 2 (PON2) due...
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Pharmacologic Therapy for Cancer Anorexia-Cachexia Syndrome

Yoon S, Kim H

Cancer-related anorexia-cachexia syndrome (CACS) is a hypercatabolic state, characterized by reduced appetite and weight loss due to ongoing loss of skeletal muscle mass and adipose tissue. CACS occurs mainly in...
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Effect of eicosapentanoic acid on neutrophil-endothelial adhesion

Kwon YD, Hwang JB, Han CH, Chung HL, Lee SJ, An YH

  • KMID: 2365367
  • Allergy.
  • 1995 Sep;15(3):320-329.
Adhesion molecule may play a primary role in the pathogenesis of bronchial asthma. ELAM - 1 (endothelial leukocyte adhesion molecule- 1) which is a member of selectin family has known...
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Serum Lipids and Fatty Acids According to the Type of Feeding in Children

Oh KH, Park JO, Kim CH, Shin SM

  • KMID: 2335279
  • J Korean Pediatr Soc.
  • 1997 Aug;40(8):1098-1109.
PURPOSE: Lipids and fatty acids are very important for brain and nervous system in growing children. This study was carried out to compare the composition of serum lipids and fatty...
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Integrative Omics Reveals Metabolic and Transcriptomic Alteration of Nonalcoholic Fatty Liver Disease in Catalase Knockout Mice

Na J, Choi SA, Khan A, Huh JY, Piao L, Hwang I, Ha H, Park YH

The prevalence of nonalcoholic fatty liver disease (NAFLD) has increased with the incidence of obesity; however, the underlying mechanisms are unknown. In this study, high-resolution metabolomics (HRM) along with transcriptomics...
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Dietary intake of n-3 and n-6 polyunsaturated fatty acids in Korean toddlers 12–24 months of age with comparison to the dietary recommendations

Kim Y, Kim H, Kwon O

BACKGROUND/OBJECTIVES: Adequate dietary fatty acid intake is important for toddlers between 12–24 months of age, as this is a period of dietary transition in conjunction with rapid growth and development;...
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Chemopreventive and Chemotherapeutic Effects of Fish Oil derived Omega-3 Polyunsaturated Fatty Acids on Colon Carcinogenesis

Lee JY, Sim TB, Lee JE, Na HK

Colorectal cancer is the third most common cause of cancer related death in the world. Multiple lines of evidence suggest that there is an association between consumption of dietary fat...
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Low Plasma Proportion of Omega 3-Polyunsaturated Fatty Acids Predicts Poor Outcome in Acute Non-Cardiogenic Ischemic Stroke Patients

Song TJ, Cho HJ, Chang Y, Choi K, Jung AR, Youn M, Shin MJ, Kim YJ

BACKGROUND AND PURPOSE: Alterations in blood fatty acid (FA) composition are associated with cardiovascular diseases. We investigated whether plasma FA composition was related to stroke severity and functional outcome in...
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Increased Inflammation, Reduced Plasma Phospholipid Eicosapentaenoic Acid and Reduced Antioxidant Potential of Treated Hypertensive Patients with Metabolic Syndrome

Shin MJ, Shim E, Kang B, Park S, Lee SH, Shim CY, Park E, Chung N

PURPOSE: In the present study, we tested whether the presence of metabolic syndrome (MetS) would worsen the features of inflammation, plasma omega 3 fatty acid levels and antioxidant potential in...
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Serum level changes of long chain-polyunsaturated fatty acids in patients undergoing periodontal therapy combined with one year of omega-3 supplementation: a pilot randomized clinical trial

Martinez G, Koury JC, Martins MA, Nogueira F, Fischer RG, Gustafsson A, Figueredo

PURPOSE: We aimed to investigate the impact of nonsurgical periodontal treatment combined with one-year dietary supplementation with omega (omega)-3 on the serum levels of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA),...
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Effects of Omega-3 Supplementation on Adipocytokines in Prediabetes and Type 2 Diabetes Mellitus: Systematic Review and Meta-Analysis of Randomized Controlled Trials

Becic T, Studenik C

BACKGROUND: The objective of this systematic review and meta-analysis was to determine the effects of omega-3 supplementation on adipocytokine levels in adult prediabetic and diabetic individuals. METHODS: We searched PubMed, Medline,...
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Relaxation of Subarachnoid Hemorrhage-Induced Spasm by Eicosapentanoic Acid

Park SB, Kang SD, Park JT, Moon SK, Kim TY, Kim JM

  • KMID: 2018576
  • J Korean Neurosurg Soc.
  • 2002 Jun;31(6):569-573.
OBJECTIVE: There is increasing evidence that the omega-3 polyunsaturated fatty acid, eicosapentanoic acid(EPA), induces relaxation in vessels from various animal models as cardiovascular protective nutrients. In vivo study was undertaken...
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DHA and EPA Down-regulate COX-2 Expression through Suppression of NF-kappa B Activity in LPS-treated Human Umbilical Vein Endothelial Cells

Lee SA, Kim HJ, Chang KC, Baek JC, Park JK, Shin JK, Choi WJ, Lee JH, Paik WY

Inflammatory processes of vascular endothelial cells play a key role in the development ofatherosclerosis. We determined the anti-inflammatory effects and mechanisms of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on...
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Systematic review of the effect of omega-3 fatty acids on improvement of blood flow while focused on evaluation of claims for health functional food

Jeong S, Kim JY, Paek JE, Kim J, Kwak JS, Kwon O

  • KMID: 2329662
  • J Nutr Health.
  • 2013 Jun;46(3):226-238.
Omega-3 polyunsaturated fatty acids are essential fatty acids because humans cannot synthesize them de novo and must obtain them in their diet. Fish and fish oil are rich sources of...
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Association of Nutrient Intakes with Cognitive Function in Koreans Aged 50 years and Older

Kim HL, Kim DK, Kang SW, Park YK

This study attempted to investigate whether nutrient and food intake were related with mild cognitive impairment (MCI) in adults and elderly over 50 years of age in Korea. Questionnaires and...
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